Author results

2JLE
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NOVEL INDAZOLE NNRTIS CREATED USING MOLECULAR TEMPLATE HYBRIDIZATION BASED ON CRYSTALLOGRAPHIC OVERLAYS
Descriptor:REVERSE TRANSCRIPTASE/RNASEH, 5-[(5-fluoro-3-methyl-1H-indazol-4-yl)oxy]benzene-1,3-dicarbonitrile
Authors:Jones, L.H., Allan, G., Barba, O., Burt, C., Corbau, R., Dupont, T., Irving, S., Mowbray, C.E., Phillips, C., Swain, N.A., Webster, R., Westby, M.
Deposit date:2008-09-08
Release date:2009-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays.
J.Med.Chem., 52, 2009
2LDA
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SOLUTION STRUCTURE OF THE ESTROGEN RECEPTOR-BINDING STAPLED PEPTIDE SP2 (AC-HKXLHQXLQDS-NH2)
Descriptor:Estrogen receptor-binding stapled peptide SP2
Authors:Phillips, C., Bazin, R., Bent, A., Davies, N., Moore, R., Pannifer, A., Pickford, A., Prior, S., Read, C., Roberts, L., Schade, M., Scott, A., Brown, D., Xu, B., Irving, S.
Deposit date:2011-05-20
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2LDC
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SOLUTION STRUCTURE OF THE ESTROGEN RECEPTOR-BINDING STAPLED PEPTIDE SP1 (AC-HXILHXLLQDS-NH2)
Descriptor:Estrogen receptor-binding stapled peptide SP1
Authors:Phillips, C., Bazin, R., Bent, A., Davies, N., Moore, R., Pannifer, A., Pickford, A., Prior, S., Read, C., Roberts, L., Schade, M., Scott, A., Brown, D., Xu, B., Irving, S.
Deposit date:2011-05-20
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2LDD
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SOLUTION STRUCTURE OF THE ESTROGEN RECEPTOR-BINDING STAPLED PEPTIDE SP6 (AC-EKHKILXRLLXDS-NH2)
Descriptor:Estrogen receptor-binding stapled peptide SP6
Authors:Phillips, C., Bazin, R., Bent, A., Davies, N., Moore, R., Pannifer, A., Pickford, A., Prior, S., Read, C., Roberts, L., Schade, M., Scott, A., Brown, D., Xu, B., Irving, S.
Deposit date:2011-05-21
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2WOM
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CRYSTAL STRUCTURE OF UK-453061 BOUND TO HIV-1 REVERSE TRANSCRIPTASE (K103N).
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, 5-{[3,5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile
Authors:Phillips, C., Irving, S.L., Knoechel, T., Ringrose, H.
Deposit date:2009-07-27
Release date:2010-08-11
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1.
Antimicrob. Agents Chemother., 54, 2010
5L8I
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CRYSTAL STRUCTURE OF HUMAN FABP6 APO-PROTEIN
Descriptor:Gastrotropin, TRIETHYLENE GLYCOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
Authors:Hendrick, A., Mueller, I., Leonard, P.M., Davenport, R., Mitchell, P.
Deposit date:2016-06-08
Release date:2016-08-24
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6).
J.Med.Chem., 59, 2016
5L8N
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CRYSTAL STRUCTURE OF HUMAN FABP6 PROTEIN WITH FRAGMENT 1
Descriptor:Gastrotropin, 5,6-dimethyl-1~{H}-benzimidazol-2-amine, DI(HYDROXYETHYL)ETHER, ...
Authors:Hendrick, A., Mueller, I., Leonard, P.M., Davenport, R., Mitchell, P.
Deposit date:2016-06-08
Release date:2016-08-24
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6).
J.Med.Chem., 59, 2016
5L8O
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CRYSTAL STRUCTURE OF HUMAN FABP6 IN COMPLEX WITH CHOLATE
Descriptor:Gastrotropin, DI(HYDROXYETHYL)ETHER, CHOLIC ACID
Authors:Hendrick, A., Mueller, I., Leonard, P.M., Davenport, R., Mitchell, P.
Deposit date:2016-06-08
Release date:2016-08-24
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6).
J.Med.Chem., 59, 2016