Author results

1M16
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HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 141 AMINO ACID FORM WITH AMINO TERMINAL HIS TAG AND LEU 44 REPLACED WITH PHE (L44F), LEU 73 REPLACED WITH VAL (L73V), VAL 109 REPLACED WITH LEU (V109L) AND CYS 117 REPLACED WITH VAL (C117V).
Descriptor:acidic fibroblast growth factor, SULFATE ION, FORMIC ACID
Authors:Brych, S.R., Kim, J., Spielmann, G.L., Logan, T.M., Blaber, M.
Deposit date:2002-06-17
Release date:2003-08-05
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
1M9H
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CORYNEBACTERIUM 2,5-DKGR A AND PHE 22 REPLACED WITH TYR (F22Y), LYS 232 REPLACED WITH GLY (K232G), ARG 238 REPLACED WITH HIS (R238H)AND ALA 272 REPLACED WITH GLY (A272G)IN PRESENCE OF NADH COFACTOR
Descriptor:2,5-diketo-D-gluconic acid reductase A, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Sanli, G., Blaber, M.
Deposit date:2002-07-29
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductase
Protein Sci., 13, 2004
1NZK
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CRYSTAL STRUCTURE OF A MULTIPLE MUTANT (L44F, L73V, V109L, L111I, C117V) OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Acidic Fibroblast Growth Factor, SULFATE ION, FORMIC ACID
Authors:Brych, S.R., Kim, J., Logan, T.M., Blaber, M.
Deposit date:2003-02-18
Release date:2004-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold.
Protein Sci., 12, 2003
1P63
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HUMAN ACIDIC FIBROBLAST GROWTH FACTOR. 140 AMINO ACID FORM WITH AMINO TERMINAL HIS TAG AND LEU111 REPLACED WITH ILE (L111I)
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR, SULFATE ION, FORMIC ACID
Authors:Brych, S.R., Kim, J., Logan, T.M., Blaber, M.
Deposit date:2003-04-28
Release date:2004-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
1PZZ
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CRYSTAL STRUCTURE OF FGF-1, V51N MUTANT
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Kim, J., Blaber, M.
Deposit date:2003-07-14
Release date:2004-07-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
1Q03
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CRYSTAL STRUCTURE OF FGF-1, S50G/V51G MUTANT
Descriptor:Heparin-binding growth factor 1
Authors:Kim, J., Blaber, M.
Deposit date:2003-07-15
Release date:2004-07-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
1Q04
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CRYSTAL STRUCTURE OF FGF-1, S50E/V51N
Descriptor:Heparin-binding growth factor 1, FORMIC ACID
Authors:Kim, J., Blaber, M.
Deposit date:2003-07-15
Release date:2004-07-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
1RG8
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HUMAN ACIDIC FIBROBLAST GROWTH FACTOR (HAFGF-1) AT 1.10 ANGSTROM RESOLUTION (140 AMINO ACID FORM)
Descriptor:Heparin-binding growth factor 1, FORMIC ACID
Authors:Bernett, M.J., Somasundaram, T., Blaber, M.
Deposit date:2003-11-11
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:An atomic resolution structure for human fibroblast growth factor 1.
Proteins, 57, 2004
1YTO
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CRYSTAL STRUCTURE OF GLY19 DELETION MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Lee, J., Blaber, M.
Deposit date:2005-02-10
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
1Z2V
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CRYSTAL STRUCTURE OF GLU60 DELETION MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J., Blaber, M.
Deposit date:2005-03-09
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
1Z4S
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CRYSTAL STRUCTURE OF GLY19 AND GLU60 DELETION MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J., Blaber, M.
Deposit date:2005-03-16
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2005
2AQZ
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CRYSTAL STRUCTURE OF FGF-1, S17T/N18T/G19 DELETION MUTANT
Descriptor:Heparin-binding growth factor 1, SULFATE ION
Authors:Lee, J., Blaber, M.
Deposit date:2005-08-18
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
3BAG
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CRYSTAL STRUCTURE OF K112N/N114A MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, FORMIC ACID
Authors:Lee, J., Blaber, M.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAH
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CRYSTAL STRUCTURE OF K112N MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, FORMIC ACID
Authors:Lee, J., Blaber, M.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAO
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CRYSTAL STRUCTURE OF L26N MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Lee, J., Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAQ
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CRYSTAL STRUCTURE OF L26A MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Lee, J., Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAU
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CRYSTAL STRUCTURE OF K12V/L26D/D28A MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Lee, J., Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAV
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CRYSTAL STRUCTURE OF L26A/D28N MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Lee, J., Blaber, M.
Deposit date:2007-11-08
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BB2
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CRYSTAL STRUCTURE OF L26D/D28N MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Lee, J., Blaber, M.
Deposit date:2007-11-09
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3O49
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CRYSTAL STRUCTURE OF SYMFOIL-1: DE NOVO DESIGNED BETA-TREFOIL ARCHITECTURE WITH SYMMETRIC PRIMARY STRUCTURE
Descriptor:de novo designed beta-trefoil architecture with symmetric primary structure, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION
Authors:Lee, J., Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O4A
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CRYSTAL STRUCTURE OF SYMFOIL-2: DE NOVO DESIGNED BETA-TREFOIL ARCHITECTURE WITH SYMMETRIC PRIMARY STRUCTURE
Descriptor:de novo designed beta-trefoil architecture with symmetric primary structure, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION
Authors:Lee, J., Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O4B
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CRYSTAL STRUCTURE OF SYMFOIL-4T: DE NOVO DESIGNED BETA-TREFOIL ARCHITECTURE WITH SYMMETRIC PRIMARY STRUCTURE
Descriptor:de novo designed beta-trefoil architecture with symmetric primary structure, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ...
Authors:Lee, J., Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O4C
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CRYSTAL STRUCTURE OF SYMFOIL-4V: DE NOVO DESIGNED BETA-TREFOIL ARCHITECTURE WITH SYMMETRIC PRIMARY STRUCTURE
Descriptor:de novo designed beta-trefoil architecture with symmetric primary structure, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ...
Authors:Lee, J., Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3O4D
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CRYSTAL STRUCTURE OF SYMFOIL-4P: DE NOVO DESIGNED BETA-TREFOIL ARCHITECTURE WITH SYMMETRIC PRIMARY STRUCTURE
Descriptor:de novo designed beta-trefoil architecture with symmetric primary structure, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ...
Authors:Lee, J., Blaber, M.
Deposit date:2010-07-26
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OGF
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CRYSTAL STRUCTURE OF DIFOIL-4P HOMO-TRIMER: DE NOVO DESIGNED DIMERIC TREFOIL-FOLD SUB-DOMAIN WHICH FORMS HOMO-TRIMER ASSEMBLY
Descriptor:de novo designed dimeric trefoil-fold sub-domain which forms homo-trimer assembly, SULFATE ION
Authors:Lee, J., Blaber, M.
Deposit date:2010-08-16
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.864 Å)
Cite:Experimental support for the evolution of symmetric protein architecture from a simple peptide motif.
Proc.Natl.Acad.Sci.USA, 108, 2011