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6DFW
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TCR 8F10 IN COMPLEX WITH IAG7-P8G9E
分子名称:H-2 class II histocompatibility antigen, A-D alpha chain, H2-Ab1 protein, ...
著者Wang, Y., Dai, S.
登録日2018-05-15
公開日2019-04-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFX
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HUMAN DIABETOGENIC TCR T1D3 IN COMPLEX WITH DQ8-P8E9E PEPTIDE
分子名称:MHC class II HLA-DQ-alpha chain, MHC class II antigen, T1D3 alpha chain, ...
著者Wang, Y., Dai, S.
登録日2018-05-15
公開日2019-04-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
5HHT
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CRYSTAL STRUCTURE OF E. COLI TRANSKETOLASE TRIPLE VARIANT SER385TYR/ASP469THR/ARG520GLN
分子名称:Transketolase 1, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Dai, S., Tittmann, K.
登録日2016-01-11
公開日2016-11-02
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes.
Sci Rep, 6, 2016
5XFF
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CRYSTAL STRUCTURE OF LY2874455 IN COMPLEX OF FGFR4 GATEKEEPER MUTATION (V550L)
分子名称:Fibroblast growth factor receptor 4, 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol
著者Wu, D., Chen, Y.
登録日2017-04-10
公開日2018-09-05
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance.
Chem. Commun. (Camb.), 54, 2018
5XFJ
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CRYSTAL STRUCTURE OF LY2874455 IN COMPLEX OF FGFR4 GATEKEEPER MUTATION (V550M)
分子名称:Fibroblast growth factor receptor 4, 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol
著者Wu, D., Chen, Y.
登録日2017-04-10
公開日2018-08-08
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance.
Chem. Commun. (Camb.), 54, 2018
1OQD
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CRYSTAL STRUCTURE OF STALL-1 AND BCMA
分子名称:Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 17
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1OQE
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CRYSTAL STRUCTURE OF STALL-1 WITH BAFF-R
分子名称:Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 13C
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
2P5B
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THE COMPLEX STRUCTURE OF JMJD2A AND TRIMETHYLATED H3K36 PEPTIDE
分子名称:JmjC domain-containing histone demethylation protein 3A, Histone H3, ZINC ION, ...
著者Zhang, G., Chen, Z., Zang, J., Hong, X., Shi, Y.
登録日2007-03-14
公開日2007-06-12
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
2PXJ
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THE COMPLEX STRUCTURE OF JMJD2A AND MONOMETHYLATED H3K36 PEPTIDE
分子名称:JmjC domain-containing histone demethylation protein 3A, monomethylated Histone H3K36 peptide, ZINC ION, ...
著者Chen, Z., Zang, J., Kappler, J., Hong, X., Crawford, F., Zhang, G.
登録日2007-05-14
公開日2007-06-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of the recognition of a methylated histone tail by JMJD2A
Proc.Natl.Acad.Sci.Usa, 104, 2007
3LD8
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STRUCTURE OF JMJD6 AND FAB FRAGMENTS
分子名称:Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, antibody Fab fragment light chain, antibody Fab fragment heavy chain, ...
著者Hong, X., Zang, J., White, J., Kappler, J.W., Wang, C., Zhang, G.
登録日2010-01-12
公開日2010-08-04
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Interaction of JMJD6 with single-stranded RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LDB
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STRUCTURE OF JMJD6 COMPLEXD WITH ALPHA-KETOGLUTARATE AND FAB FRAGMENT.
分子名称:Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, antibody Fab fragment light chain, antibody Fab fragment heavy chain, ...
著者Hong, X., Zang, J., White, J., Kappler, J.W., Wang, C., Zhang, G.
登録日2010-01-12
公開日2010-08-04
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Interaction of JMJD6 with single-stranded RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
4KEG
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CRYSTAL STRUCTURE OF MBP FUSED HUMAN SPLUNC1
分子名称:Maltose-binding periplasmic/Palate lung and nasal epithelium clone fusion protein, B-OCTYLGLUCOSIDE, MAGNESIUM ION
著者Ning, F., Wang, C., Niu, L., Chu, H.W., Zhang, G.
登録日2013-04-25
公開日2014-04-30
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Lipid Ligands of the SPLUNC1 Protein
To be Published
4P4K
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STRUCTURAL BASIS OF CHRONIC BERYLLIUM DISEASE: BRIDGING THE GAP BETWEEN ALLERGIC HYPERSENSITIVITY AND AUTO IMMUNITY
分子名称:HLA class II histocompatibility antigen, DP alpha 1 chain, mim2 peptide,HLA class II histocompatibility antigen, ...
著者Clayton, G.M., Crawford, F., Kappler, J.W.
登録日2014-03-12
公開日2014-07-16
最終更新日2015-01-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
4P4R
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STRUCTURAL BASIS OF CHRONIC BERYLLIUM DISEASE: BRIDGING THE GAP BETWEEN ALLERGIC HYPERSENSITIVITY AND AUTOIMMUNITY
分子名称:HLA class II histocompatibility antigen, DP alpha 1 chain, mim2 peptide,HLA class II histocompatibility antigen, ...
著者Clayton, G.M., Crawford, F., Kappler, J.W.
登録日2014-03-13
公開日2014-07-16
最終更新日2015-01-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
4P57
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MHC TCR PEPTIDE COMPLEX
分子名称:HLA class II histocompatibility antigen, DP alpha 1 chain, mim2 peptide,HLA class II histocompatibility antigen, ...
著者Clayton, G.M., Crawford, F., Kappler, J.W.
登録日2014-03-14
公開日2014-07-16
最終更新日2015-01-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
5XP5
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C-SRC IN COMPLEX WITH ATP-CHF
分子名称:Proto-oncogene tyrosine-protein kinase Src, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-[(S)-fluoranyl-[oxidanyl(phosphonooxy)phosphoryl]methyl]phosphinic acid, MAGNESIUM ION
著者Duan, Y., Guo, M., Dai, S., Chen, L., Chen, Y.
登録日2017-06-01
公開日2018-02-07
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Remarkably Stereospecific Utilization of ATP alpha , beta-Halomethylene Analogues by Protein Kinases.
J. Am. Chem. Soc., 139, 2017
5XP7
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C-SRC IN COMPLEX WITH ATP-CHCL
分子名称:Proto-oncogene tyrosine-protein kinase Src, [(R)-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]-chloranyl-methyl]phosphonic acid, MAGNESIUM ION, ...
著者Guo, M., Dai, S., Duan, Y., Chen, L., Chen, Y.
登録日2017-06-01
公開日2017-09-06
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.012 Å)
主引用文献Remarkably Stereospecific Utilization of ATP alpha , beta-Halomethylene Analogues by Protein Kinases.
J. Am. Chem. Soc., 139, 2017
5ZOV
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INWARD-FACING CONFORMATION OF L-ASCORBATE TRANSPORTER ULAA
分子名称:PTS ascorbate-specific subunit IIBC, ASCORBIC ACID, CALCIUM ION
著者Wang, J.W.
登録日2018-04-16
公開日2018-08-01
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (3.333 Å)
主引用文献Inward-facing conformation of l-ascorbate transporter suggests an elevator mechanism
Cell Discov, 4, 2018
6JPJ
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CRYSTAL STRUCTURE OF FGF401 IN COMPLEX OF FGFR4
分子名称:Fibroblast growth factor receptor 4, N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide, SULFATE ION
著者Zhou, Z., Chen, X., Chen, Y.
登録日2019-03-27
公開日2019-05-15
最終更新日2019-06-05
実験手法X-RAY DIFFRACTION (2.638 Å)
主引用文献Characterization of FGF401 as a reversible covalent inhibitor of fibroblast growth factor receptor 4.
Chem.Commun.(Camb.), 55, 2019
4YK9
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COMPLEX STRUCTURE OF BCL-XL AND MUTATED BIM BH3 DOMAIN
分子名称:Bcl-2-like protein 1, BH3BIM, ACETATE ION, ...
著者Ha, N.C., Kim, J.S.
登録日2015-03-04
公開日2016-04-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Complex structure of BCL-XL and mutated BIM BH3 domain
To be published
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