Author results

5DMK
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CRYSTAL STRUCTURE OF IAG7 IN COMPLEX WITH RLGL-WE14
分子名称:H-2 class II histocompatibility antigen, A-D alpha chain, beta chain of Major Histocompatibility Complex Class II, ...
著者Wang, Y., Jin, N., Dai, S., Kappler, J.W.
登録日2015-09-08
公開日2015-10-28
最終更新日2016-04-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.
Proc.Natl.Acad.Sci.USA, 112, 2015
5UJT
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CRYSTAL STRUCTURE OF HUMAN HLA-DQ8 IN COMPLEX WITH INSULIN MIMOTOPE BINDING IN REGISTER 3
分子名称:MHC class II antigen, MHC class II HLA-DQ-beta-1, insulin mimotope, ...
著者Wang, Y., Dai, S.
登録日2017-01-18
公開日2017-12-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W1J
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ECHINOCOCCUS GRANULOSUS THIOREDOXIN GLUTATHIONE REDUCTAS (EGTGR)
分子名称:Thioredoxin glutathione reductase, FLAVIN-ADENINE DINUCLEOTIDE
著者Gao, W., Wang, Y., Dai, S.
登録日2017-06-03
公開日2017-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I).
Antioxid. Redox Signal., 27, 2017
5W1L
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ECHINOCOCCUS GRANULOSUS THIOREDOXIN GLUTATHIONE REDUCTAS (EGTGR) WITH GOLD
分子名称:Thioredoxin glutathione reductase, FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION
著者Gao, W., Wang, Y., Dai, S.
登録日2017-06-03
公開日2017-11-22
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I).
Antioxid. Redox Signal., 27, 2017
6AKO
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CRYSTAL STRUCTURE OF FOXC2 DBD BOUND TO DBE2 DNA
分子名称:DNA (5'-D(CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Forkhead box protein C2, ...
著者Chen, X., Wei, H., Li, J., Liang, X., Dai, S., Jiang, L., Guo, M., Chen, Y.
登録日2018-09-03
公開日2019-02-06
最終更新日2019-05-01
実験手法X-RAY DIFFRACTION (2.396 Å)
主引用文献Structural basis for DNA recognition by FOXC2.
Nucleic Acids Res., 47, 2019
6AKP
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CRYSTAL STRUCTURAL OF FOXC2 DNA BINDING DOMAIN BOUND TO PC PROMOTER
分子名称:DNA (5'-D(AP*CP*AP*CP*AP*AP*AP*TP*AP*TP*TP*TP*GP*TP*GP*T)-3'), Forkhead box protein C2, MAGNESIUM ION
著者Chen, X., Wei, H., Li, J., Liang, X., Dai, S., Jiang, L., Guo, M., Chen, Y.
登録日2018-09-03
公開日2019-02-06
最終更新日2019-05-01
実験手法X-RAY DIFFRACTION (2.323 Å)
主引用文献Structural basis for DNA recognition by FOXC2.
Nucleic Acids Res., 47, 2019
6BLQ
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CRYSTAL STRUCTURE OF IAG7 IN COMPLEX WITH INSULIN MIMOTOPE P8E9E
分子名称:H-2 class II histocompatibility antigen, A-D alpha chain, H2-Ab1 protein, ...
著者Wang, Y., Dai, S.
登録日2017-11-11
公開日2017-12-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BLR
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CRYSTAL STRUCTURE OF IAG7 IN COMPLEX WITH INSULIN MIMOTOPE P8E9E6SS
分子名称:IAg7 alpha chain, H2-Ab1 protein, 1,2-ETHANEDIOL
著者Wang, Y., Dai, S.
登録日2017-11-11
公開日2017-12-20
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BLX
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CRYSTAL STRUCTURE OF IAG7 IN COMPLEX WITH INSULIN MIMOTOPE P8G9E
分子名称:H-2 class II histocompatibility antigen, A-D alpha chain, H2-Ab1 protein, ...
著者Wang, Y., Dai, S.
登録日2017-11-11
公開日2017-12-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.323 Å)
主引用文献C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DFQ
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MOUSE DIABETOGENIC TCR I.29
分子名称:TCR alpha chain, TCR beta chain, CALCIUM ION, ...
著者Wang, Y., Dai, S.
登録日2018-05-15
公開日2019-04-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFS
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MOUSE TCR I.29 IN COMPLEX WITH IAG7-P8E9E6SS
分子名称:mouse TCR alpha chain, mouse TCR beta chain, H-2 class II histocompatibility antigen, ...
著者Wang, Y., Dai, S.
登録日2018-05-15
公開日2019-04-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFV
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MOUSE DIABETOGENIC TCR 8F10
分子名称:TCR alpha chain, TCR beta chain, 1,2-ETHANEDIOL
著者Wang, Y., Dai, S.
登録日2018-05-15
公開日2019-04-17
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFW
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TCR 8F10 IN COMPLEX WITH IAG7-P8G9E
分子名称:H-2 class II histocompatibility antigen, A-D alpha chain, H2-Ab1 protein, ...
著者Wang, Y., Dai, S.
登録日2018-05-15
公開日2019-04-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
6DFX
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HUMAN DIABETOGENIC TCR T1D3 IN COMPLEX WITH DQ8-P8E9E PEPTIDE
分子名称:MHC class II HLA-DQ-alpha chain, MHC class II antigen, T1D3 alpha chain, ...
著者Wang, Y., Dai, S.
登録日2018-05-15
公開日2019-04-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
Sci Immunol, 4, 2019
5HHT
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CRYSTAL STRUCTURE OF E. COLI TRANSKETOLASE TRIPLE VARIANT SER385TYR/ASP469THR/ARG520GLN
分子名称:Transketolase 1, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Dai, S., Tittmann, K.
登録日2016-01-11
公開日2016-11-02
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Analysis of an Evolved Transketolase Reveals Divergent Binding Modes.
Sci Rep, 6, 2016
6HAF
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PYRUVATE OXIDASE VARIANT E59Q FROM L. PLANTARUM IN COMPLEX WITH PHOSPHATE
分子名称:Pyruvate oxidase, FLAVIN-ADENINE DINUCLEOTIDE, POTASSIUM ION, ...
著者Funk, L.M., Sautner, V., Tittmann, K.
登録日2018-08-07
公開日2019-08-21
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019
6RJB
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HUMAN TRANSKETOLASE VARIANT T382E
分子名称:Transketolase, THIAMIN DIPHOSPHATE, MAGNESIUM ION, ...
著者Rabe von Pappenheim, F., Tittmann, K.
登録日2019-04-26
公開日2019-09-11
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019
6RJC
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E.COLI TRANSKETOLASE APOENZYME
分子名称:Transketolase 1, CALCIUM ION, 1,2-ETHANEDIOL, ...
著者Rabe von Pappenheim, F., Tittmann, K.
登録日2019-04-26
公開日2019-09-11
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Low-barrier hydrogen bonds in enzyme cooperativity.
Nature, 573, 2019
5XFF
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CRYSTAL STRUCTURE OF LY2874455 IN COMPLEX OF FGFR4 GATEKEEPER MUTATION (V550L)
分子名称:Fibroblast growth factor receptor 4, 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol
著者Wu, D., Chen, Y.
登録日2017-04-10
公開日2018-09-05
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance.
Chem. Commun. (Camb.), 54, 2018
5XFJ
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CRYSTAL STRUCTURE OF LY2874455 IN COMPLEX OF FGFR4 GATEKEEPER MUTATION (V550M)
分子名称:Fibroblast growth factor receptor 4, 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol
著者Wu, D., Chen, Y.
登録日2017-04-10
公開日2018-08-08
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献LY2874455 potently inhibits FGFR gatekeeper mutants and overcomes mutation-based resistance.
Chem. Commun. (Camb.), 54, 2018
1OQD
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CRYSTAL STRUCTURE OF STALL-1 AND BCMA
分子名称:Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 17
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1OQE
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CRYSTAL STRUCTURE OF STALL-1 WITH BAFF-R
分子名称:Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 13C
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
2P5B
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THE COMPLEX STRUCTURE OF JMJD2A AND TRIMETHYLATED H3K36 PEPTIDE
分子名称:JmjC domain-containing histone demethylation protein 3A, Histone H3, ZINC ION, ...
著者Zhang, G., Chen, Z., Zang, J., Hong, X., Shi, Y.
登録日2007-03-14
公開日2007-06-12
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
2PXJ
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THE COMPLEX STRUCTURE OF JMJD2A AND MONOMETHYLATED H3K36 PEPTIDE
分子名称:JmjC domain-containing histone demethylation protein 3A, monomethylated Histone H3K36 peptide, ZINC ION, ...
著者Chen, Z., Zang, J., Kappler, J., Hong, X., Crawford, F., Zhang, G.
登録日2007-05-14
公開日2007-06-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of the recognition of a methylated histone tail by JMJD2A
Proc.Natl.Acad.Sci.Usa, 104, 2007
3LD8
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STRUCTURE OF JMJD6 AND FAB FRAGMENTS
分子名称:Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, antibody Fab fragment light chain, antibody Fab fragment heavy chain, ...
著者Hong, X., Zang, J., White, J., Kappler, J.W., Wang, C., Zhang, G.
登録日2010-01-12
公開日2010-08-04
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Interaction of JMJD6 with single-stranded RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
167327
件を2020-08-05に公開中