7L9P
| Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex | Descriptor: | Mitotic spindle assembly checkpoint protein MAD2B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Pachytene checkpoint protein 2 homolog, ... | Authors: | Xie, W, Patel, D.J. | Deposit date: | 2021-01-04 | Release date: | 2021-03-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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6F0X
| Cryo-EM structure of TRIP13 in complex with ATP gamma S, p31comet, C-Mad2 and Cdc20 | Descriptor: | Cell division cycle protein 20 homolog, MAD2L1-binding protein, Mitotic spindle assembly checkpoint protein MAD2A, ... | Authors: | Alfieri, C, Chang, L, Barford, D. | Deposit date: | 2017-11-20 | Release date: | 2018-05-02 | Last modified: | 2020-12-02 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13. Nature, 559, 2018
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5WC2
| Crystal Structure of ADP-bound human TRIP13 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Pachytene checkpoint protein 2 homolog | Authors: | Jeong, B.-C, Luo, X. | Deposit date: | 2017-06-29 | Release date: | 2018-04-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing. Nat Commun, 8, 2017
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6LK0
| Crystal structure of human wild type TRIP13 | Descriptor: | Pachytene checkpoint protein 2 homolog | Authors: | Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J. | Deposit date: | 2019-12-17 | Release date: | 2020-01-22 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression. Cancer Res., 80, 2020
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4XGU
| Structure of C. elegans PCH-2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Putative pachytene checkpoint protein 2, SULFATE ION | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2015-01-02 | Release date: | 2015-05-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. Elife, 4, 2015
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5VQ9
| Structure of human TRIP13, Apo form | Descriptor: | Pachytene checkpoint protein 2 homolog | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2017-05-08 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | The AAA+ ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding. EMBO J., 36, 2017
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5VQA
| Structure of human TRIP13, ATP-bound form | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Pachytene checkpoint protein 2 homolog | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2017-05-08 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | The AAA+ ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding. EMBO J., 36, 2017
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6P8V
| Structure of E. coli MS115-1 HORMA:CdnC:Trip13 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATPase, AAA family, ... | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2019-06-08 | Release date: | 2019-12-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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6PB3
| Structure of Rhizobiales Trip13 | Descriptor: | Rhizobiales Sp. Pch2, SULFATE ION | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2019-06-12 | Release date: | 2019-12-25 | Last modified: | 2020-03-04 | Method: | X-RAY DIFFRACTION (2.048 Å) | Cite: | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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6WWA
| Crystal structure of human SHLD2-SHLD3-REV7 complex | Descriptor: | Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2,Shieldin complex subunit 3 chimera | Authors: | Xie, W, Patel, D.J. | Deposit date: | 2020-05-08 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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6WW9
| Crystal structure of human REV7(R124A)-SHLD3(35-58) complex | Descriptor: | Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3 | Authors: | Xie, W, Patel, D.J. | Deposit date: | 2020-05-08 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex. Proc.Natl.Acad.Sci.USA, 118, 2021
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6U7B
| Structure of E. coli MS115-1 CdnC:HORMA-deltaN complex | Descriptor: | ACETATE ION, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2019-09-02 | Release date: | 2019-12-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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6P80
| Structure of E. coli MS115-1 CdnC + ATP | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | Authors: | Ye, Q, Azimi, C.S, Corbett, K.D. | Deposit date: | 2019-06-06 | Release date: | 2019-12-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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6P8P
| Structure of P. aeruginosa ATCC27853 HORMA1 | Descriptor: | CALCIUM ION, Uncharacterized protein | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2019-06-07 | Release date: | 2019-12-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.635 Å) | Cite: | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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6P8R
| Structure of P. aeruginosa ATCC27853 HORMA2 | Descriptor: | HORMA domain containing protein, PHOSPHATE ION | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2019-06-07 | Release date: | 2019-12-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.141 Å) | Cite: | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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6P82
| Structure of P. aeruginosa ATCC27853 CdnD, Apo form 1 | Descriptor: | Nucleotidyltransferase, SULFATE ION | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2019-06-06 | Release date: | 2019-12-25 | Last modified: | 2020-03-04 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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6P8O
| Structure of P. aeruginosa ATCC27853 HORMA2-deltaC | Descriptor: | CHLORIDE ION, HORMA domain containing protein, NICKEL (II) ION | Authors: | Ye, Q, Corbett, K.D, Lau, R.K. | Deposit date: | 2019-06-07 | Release date: | 2019-12-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.604 Å) | Cite: | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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6P8J
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6P8U
| Structure of P. aeruginosa ATCC27853 CdnD:HORMA2:Peptide 1 complex | Descriptor: | HORMA domain containing protein, MAGNESIUM ION, Nucleotidyltransferase, ... | Authors: | Ye, Q, Corbett, K.D. | Deposit date: | 2019-06-08 | Release date: | 2019-12-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.893 Å) | Cite: | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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6P8S
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