4GU5
| Structure of Full-length Drosophila Cryptochrome | Descriptor: | Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION | Authors: | Zoltowski, B.D, Vaidya, A.T, Top, D, Widom, J, Young, M.W, Levy, C, Jones, A.R, Scrutton, N.S, Leys, D, Crane, B.R. | Deposit date: | 2012-08-29 | Release date: | 2012-09-26 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Updated structure of Drosophila cryptochrome. Nature, 495, 2013
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6FN2
| X-ray structure of animal-like Cryptochrome from Chlamydomonas reinhardtii | Descriptor: | 8-HYDROXY-10-(D-RIBO-2,3,4,5-TETRAHYDROXYPENTYL)-5-DEAZAISOALLOXAZINE, CHLORIDE ION, Cryptochrome photoreceptor, ... | Authors: | Franz, S, Ignatz, E, Wenzel, S, Zielosko, H, Yamamoto, J, Mittag, M, Essen, L.-O. | Deposit date: | 2018-02-02 | Release date: | 2018-08-01 | Last modified: | 2018-09-19 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii. Nucleic Acids Res., 46, 2018
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4JZY
| Crystal structures of Drosophila Cryptochrome | Descriptor: | AMMONIUM ION, Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Czarna, A, Wolf, E. | Deposit date: | 2013-04-03 | Release date: | 2013-06-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function. Cell(Cambridge,Mass.), 153, 2013
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7D19
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1U3D
| Crystal Structure of the PHR domain of Cryptochrome 1 from Arabidopsis thaliana with AMPPNP bound | Descriptor: | CHLORIDE ION, Cryptochrome 1 apoprotein, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ... | Authors: | Brautigam, C.A, Smith, B.S, Ma, Z, Palnitkar, M, Tomchick, D.R, Machius, M, Deisenhofer, J. | Deposit date: | 2004-07-21 | Release date: | 2004-08-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana. Proc.Natl.Acad.Sci.USA, 101, 2004
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4CT0
| Crystal Structure of Mouse Cryptochrome1 in Complex with Period2 | Descriptor: | CHLORIDE ION, CRYPTOCHROME-1, HEXAETHYLENE GLYCOL, ... | Authors: | Schmalen, I, Rajan Prabu, J, Benda, C, Wolf, E. | Deposit date: | 2014-03-11 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Interaction of Circadian Clock Proteins Cry1 and Per2 is Modulated by Zinc Binding and Disulfide Bond Formation. Cell(Cambridge,Mass.), 157, 2014
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6K8K
| Crystal structure of Arabidopsis thaliana BIC2-CRY2 complex | Descriptor: | ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Wang, X, Ma, L, Guan, Z, Yin, P. | Deposit date: | 2019-06-12 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2. Nat.Struct.Mol.Biol., 27, 2020
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7X0X
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8P4X
| FAD_ox bound dark state structure of PdLCry | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, Putative light-receptive cryptochrome (Fragment) | Authors: | Behrmann, E, Behrmann, H. | Deposit date: | 2023-05-23 | Release date: | 2023-11-08 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | A marine cryptochrome with an inverse photo-oligomerization mechanism. Nat Commun, 14, 2023
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6WTB
| Sort-Tagged Drosophila Cryptochrome | Descriptor: | Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION | Authors: | Schneps, C.M, Crane, B.R. | Deposit date: | 2020-05-02 | Release date: | 2021-05-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Tuning flavin environment to detect and control light-induced conformational switching in Drosophila cryptochrome. Commun Biol, 4, 2021
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1U3C
| Crystal Structure of the PHR domain of Cryptochrome 1 from Arabidopsis thaliana | Descriptor: | CHLORIDE ION, Cryptochrome 1 apoprotein, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ... | Authors: | Brautigam, C.A, Smith, B.S, Ma, Z, Palnitkar, M, Tomchick, D.R, Machius, M, Deisenhofer, J. | Deposit date: | 2004-07-21 | Release date: | 2004-08-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana. Proc.Natl.Acad.Sci.USA, 101, 2004
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7EJ9
| Alternative crystal structure of mouse Cryptochrome 2 in complex with TH301 compound | Descriptor: | 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2 | Authors: | Miller, S.A, Hirota, T. | Deposit date: | 2021-04-01 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation. Proc.Natl.Acad.Sci.USA, 118, 2021
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2J08
| Thermus DNA photolyase with 8-Iod-riboflavin antenna chromophore | Descriptor: | 1-DEOXY-1-(8-IODO-7-METHYL-2,4-DIOXO-3,4-DIHYDROBENZO[G]PTERIDIN-10(2H)-YL)-D-RIBITOL, CHLORIDE ION, DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, ... | Authors: | Klar, T, Kaiser, G, Hennecke, U, Carell, T, Batschauer, A, Essen, L.-O. | Deposit date: | 2006-08-01 | Release date: | 2007-05-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Natural and Non-Natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus Chembiochem, 7, 2006
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4K0R
| Crystal structure of mouse Cryptochrome 1 | Descriptor: | Cryptochrome-1 | Authors: | Czarna, A, Wolf, E. | Deposit date: | 2013-04-04 | Release date: | 2013-06-26 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function. Cell(Cambridge,Mass.), 153, 2013
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6K8I
| Crystal structure of Arabidopsis thaliana CRY2 | Descriptor: | Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Ma, L, Wang, X, Guan, Z, Yin, P. | Deposit date: | 2019-06-12 | Release date: | 2020-05-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.697 Å) | Cite: | Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2. Nat.Struct.Mol.Biol., 27, 2020
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3FY4
| (6-4) Photolyase Crystal Structure | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-4 photolyase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Hitomi, K, Arvai, A.S, Tainer, J.A, Getzoff, E.D. | Deposit date: | 2009-01-21 | Release date: | 2009-04-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes. Proc.Natl.Acad.Sci.USA, 106, 2009
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3CVY
| Drosophila melanogaster (6-4) photolyase bound to repaired ds DNA | Descriptor: | DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T. | Deposit date: | 2008-04-20 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and mechanism of a DNA (6-4) photolyase. Angew.Chem.Int.Ed.Engl., 47, 2008
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4I6E
| A vertebrate cryptochrome | Descriptor: | Cryptochrome-2 | Authors: | Xing, W, Busino, L, Hinds, T.R, Marionni, S.T, Saifee, N.H, Bush, M.F, Pagano, M, Zheng, N. | Deposit date: | 2012-11-29 | Release date: | 2013-03-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket. Nature, 496, 2013
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4I6J
| A ubiquitin ligase-substrate complex | Descriptor: | Cryptochrome-2, F-box/LRR-repeat protein 3, S-phase kinase-associated protein 1 | Authors: | Xing, W, Busino, L, Hinds, T.R, Marionni, S.T, Saifee, N.H, Bush, M.F, Pagano, M, Zheng, N. | Deposit date: | 2012-11-29 | Release date: | 2013-03-13 | Last modified: | 2013-05-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket. Nature, 496, 2013
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4U8H
| Crystal Structure of Mammalian Period-Cryptochrome Complex | Descriptor: | Cryptochrome-2, Period circadian protein homolog 2, ZINC ION | Authors: | Nangle, S.N, Rosensweig, C, Koike, N, Tei, H, Takahashi, J.S, Green, C.B, Zheng, N. | Deposit date: | 2014-08-03 | Release date: | 2014-10-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.798 Å) | Cite: | Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex. Elife, 3, 2014
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7D0N
| Crystal structure of mouse CRY2 apo form | Descriptor: | Cryptochrome-2 | Authors: | Miller, S.A, Aikawa, Y, Hirota, T. | Deposit date: | 2020-09-11 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation. Proc.Natl.Acad.Sci.USA, 118, 2021
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2E0I
| Crystal structure of archaeal photolyase from Sulfolobus tokodaii with two FAD molecules: Implication of a novel light-harvesting cofactor | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 432aa long hypothetical deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Fujihashi, M, Numoto, N, Kobayashi, Y, Mizushima, A, Tsujimura, M, Nakamura, A, Kawarabayashi, Y, Miki, K. | Deposit date: | 2006-10-10 | Release date: | 2006-11-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Archaeal Photolyase from Sulfolobus tokodaii with Two FAD Molecules: Implication of a Novel Light-harvesting Cofactor J.Mol.Biol., 365, 2007
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6FN0
| The animal-like Cryptochrome from Chlamydomonas reinhardtii in complex with 6-4 DNA | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Cryptochrome photoreceptor, ... | Authors: | Franz, S, Ignatz, E, Wenzel, S, Zielosko, H, Yamamoto, J, Mittag, M, Essen, L.-O. | Deposit date: | 2018-02-02 | Release date: | 2018-08-01 | Last modified: | 2018-09-19 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii. Nucleic Acids Res., 46, 2018
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2WB2
| Drosophila Melanogaster (6-4) Photolyase Bound To double stranded Dna containing a T(6-4)C Photolesion | Descriptor: | 5'-D(*AP*CP*AP*GP*CP*GP*GP*64PP*ZP*GP*CP*AP *GP*GP*T)-3', 5'-D(*TP*AP*CP*CP*TP*GP*CP*GP*AP*CP*CP*GP*CP*TP*G)-3', FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Glas, A.F, Schneider, S, Maul, M.J, Hennecke, U, Carell, T. | Deposit date: | 2009-02-20 | Release date: | 2009-03-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of Uv- Induced (6-4) and Dewar Photolesions. Chemistry, 15, 2009
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6M79
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