4I6J

A ubiquitin ligase-substrate complex

Summary for 4I6J

• Entry DOI: 10.2210/pdb4i6j/pdb
• Related: 4I6E 4I6G
• Descriptor: Cryptochrome-2, F-box/LRR-repeat protein 3, S-phase kinase-associated protein 1, ... (4 entities in total)
• Functional Keywords: circadian clock, ubiquitination, lrr, f-box, photolyase fold, periods, nucleus, transcription
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm: Q9R194; Nucleus: Q9UKT7
• Total number of polymer chains: 3
• Total formula weight: 129292.57

Authors

Xing, W.,Busino, L.,Hinds, T.R.,Marionni, S.T.,Saifee, N.H.,Bush, M.F.,Pagano, M.,Zheng, N. (deposition date: 2012-11-29, release date: 2013-03-13, Last modification date: 2013-05-01)

• Primary citation: Xing, W.,Busino, L.,Hinds, T.R.,Marionni, S.T.,Saifee, N.H.,Bush, M.F.,Pagano, M.,Zheng, N.; SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket.; Nature, 496:64-68, 2013; PubMed: 23503662; DOI: 10.1038/nature11964

Experimental method

X-RAY DIFFRACTION (2.7 Å)