PDB: 205 resultsInfo pagesStatus searchChemie searchBIRD

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4Z0V	The structure of human PDE12 residues 161-609 Descriptor: 2',5'-phosphodiesterase 12, GLYCEROL, MAGNESIUM ION Authors: Nolte, R.T, Wisely, B, Wang, L, Wood, E.R. Deposit date: 2015-03-26 Release date: 2015-06-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.78 Å) Cite: The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors. J.Biol.Chem., 290, 2015
4ZKF	Crystal structure of human phosphodiesterase 12 Descriptor: 2',5'-phosphodiesterase 12, MAGNESIUM ION Authors: Kim, S.Y, Kohno, T, Mori, T, Kitano, K, Hakoshima, T. Deposit date: 2015-04-30 Release date: 2015-06-17 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Crystal structure of human phosphodiesterase To Be Published
7AX1	Crystal structure of the human CCR4-CAF1 complex Descriptor: CCR4-NOT transcription complex subunit 6, CCR4-NOT transcription complex subunit 7, MAGNESIUM ION Authors: Chen, Y, Khazina, E, Weichenrieder, O. Deposit date: 2020-11-09 Release date: 2021-05-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex. Nucleic Acids Res., 49, 2021
2F2F	Crystal structure of cytolethal distending toxin (CDT) from Actinobacillus actinomycetemcomitans Descriptor: Cytolethal distending toxin A, Cytolethal distending toxin B, cytolethal distending toxin C Authors: Yamada, T, Komoto, J, Saiki, K, Konishi, K, Takusagawa, F. Deposit date: 2005-11-16 Release date: 2006-03-28 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitans Protein Sci., 15, 2006
6O1L	Architectural principles for Hfq/Crc-mediated regulation of gene expression Hfq-Crc-amiE 2:3:2 complex Descriptor: Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq Authors: Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. Deposit date: 2019-02-20 Release date: 2019-03-13 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.37 Å) Cite: Architectural principles for Hfq/Crc-mediated regulation of gene expression. Elife, 8, 2019
6O1K	Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:2:2 complex (core complex) Descriptor: Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq Authors: Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. Deposit date: 2019-02-20 Release date: 2019-03-13 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: Architectural principles for Hfq/Crc-mediated regulation of gene expression Elife, 8, 2019
6O1M	Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:4:2 complex Descriptor: Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq Authors: Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. Deposit date: 2019-02-20 Release date: 2019-03-13 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.15 Å) Cite: Architectural principles for Hfq/Crc-mediated regulation of gene expression. Elife, 8, 2019
7VOI	Structure of the human CNOT1(MIF4G)-CNOT6L-CNOT7 complex Descriptor: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 6-like, CCR4-NOT transcription complex subunit 7 Authors: Bartlam, M, Zhang, Q. Deposit date: 2021-10-13 Release date: 2022-06-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (4.38 Å) Cite: Structure of the human Ccr4-Not nuclease module using X-ray crystallography and electron paramagnetic resonance spectroscopy distance measurements. Protein Sci., 31, 2022
5TVP	SUMO2 bound to Mouse Tdp2 catalytic domain with a 5'-phosphorylated DNA ternary complex Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), ... Authors: Schellenberg, M.J, Williams, R.S. Deposit date: 2016-11-09 Release date: 2017-10-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.399 Å) Cite: ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links. Science, 357, 2017
4B8C	nuclease module of the yeast Ccr4-Not complex Descriptor: GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, GLUCOSE-REPRESSIBLE ALCOHOL DEHYDROGENASE TRANSCRIPTIONAL EFFECTOR, POLY(A) RIBONUCLEASE POP2 Authors: Basquin, J, Conti, E. Deposit date: 2012-08-26 Release date: 2012-11-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.41 Å) Cite: Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction. Mol.Cell, 48, 2012
5TVQ	Mouse Tdp2 catalytic domain bound to SUMO2 Descriptor: ACETATE ION, CALCIUM ION, Small ubiquitin-related modifier 2, ... Authors: Schellenberg, M.J, Williams, R.S. Deposit date: 2016-11-09 Release date: 2017-09-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.35 Å) Cite: ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links. Science, 357, 2017
4F1I	Crystal structure of SeMet TDP2 from Caenorhabditis elegans Descriptor: 5'-tyrosyl-DNA phosphodiesterase, GLYCEROL Authors: Shi, K, Kurahashi, K, Aihara, H. Deposit date: 2012-05-07 Release date: 2012-10-31 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Nat.Struct.Mol.Biol., 19, 2012
4GEW	Crystal structure of TDP2 from C. elegans Descriptor: 5'-tyrosyl-DNA phosphodiesterase, GLYCEROL Authors: Shi, K, Kurahashi, K, Aihara, H. Deposit date: 2012-08-02 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Nat.Struct.Mol.Biol., 19, 2012
1ATN	Atomic structure of the actin:DNASE I complex Descriptor: ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... Authors: Kabsch, W, Mannherz, H.G, Suck, D, Pai, E, Holmes, K.C. Deposit date: 1991-03-08 Release date: 1992-07-15 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Atomic structure of the actin:DNase I complex. Nature, 347, 1990
3CJC	Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with DNase I and Gelsolin-segment 1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... Authors: Sawaya, M.R, Kudryashov, D.S, Pashkov, I, Reisler, E, Yeates, T.O. Deposit date: 2008-03-12 Release date: 2008-03-25 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc.Natl.Acad.Sci.USA, 105, 2008
4K6L	Structure of Typhoid Toxin Descriptor: Cytolethal distending toxin subunit B homolog, GLYCEROL, Putative pertussis-like toxin subunit Authors: Gao, X, Song, J, Galan, J. Deposit date: 2013-04-16 Release date: 2013-07-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.393 Å) Cite: Structure and function of the Salmonella Typhi chimaeric A(2)B(5) typhoid toxin. Nature, 499, 2013
8UW3	Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state Descriptor: Complementary DNA, LINE-1 retrotransposable element ORF2 protein, THYMIDINE-5'-TRIPHOSPHATE, ... Authors: Thawani, A, Florez Ariza, A.J, Collins, K, Nogales, E. Deposit date: 2023-11-06 Release date: 2023-12-20 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Template and target-site recognition by human LINE-1 in retrotransposition. Nature, 626, 2024
8SXT	Structure of LINE-1 ORF2p with template:primer hybrid Descriptor: DNA primer, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... Authors: van Eeuwen, T, Taylor, M.S, Rout, M.P. Deposit date: 2023-05-24 Release date: 2024-01-10 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626, 2024
8SXU	Structure of LINE-1 ORF2p with an oligo(A) template Descriptor: LINE-1 retrotransposable element ORF2 protein, RNA (25-MER) Authors: van Eeuwen, T, Taylor, M.S, Rout, M.P. Deposit date: 2023-05-24 Release date: 2024-01-10 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (3.66 Å) Cite: Structures, functions and adaptations of the human LINE-1 ORF2 protein. Nature, 626, 2024
7EE6	Crystal structure of PltC toxin Descriptor: ACETONE, CITRATE ANION, Cytolethal distending toxin subunit B family protein, ... Authors: Liu, X.Y, Chen, Z, Gao, X. Deposit date: 2021-03-17 Release date: 2021-12-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin. Mbio, 13, 2022
3W3D	Crystal structure of smooth muscle G actin DNase I complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, gamma-enteric smooth muscle, ... Authors: Sakabe, N, Sakabe, K, Sasaki, K, Kondo, H, Shimomur, M. Deposit date: 2012-12-20 Release date: 2013-01-30 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Refined structure and solvent network of chicken gizzard G-actin DNase 1 complex at 1.8A resolution Acta Crystallogr.,Sect.A, 49, 1993
7U50	APE1 bound to a nucleosome core particle with AP-site at SHL-6 Descriptor: DNA (144-MER), DNA (145-MER), DNA-(apurinic or apyrimidinic site) endonuclease, ... Authors: Weaver, T.M, Freudenthal, B.D. Deposit date: 2022-03-01 Release date: 2022-09-07 Last modified: 2022-10-05 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural basis for APE1 processing DNA damage in the nucleosome. Nat Commun, 13, 2022
7NXV	Crystal structure of the complex of DNase I/G-actin/PPP1R15A_582-621 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... Authors: Yan, Y, Ron, D. Deposit date: 2021-03-19 Release date: 2021-09-29 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
7NZM	Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... Authors: Yan, Y, Hardwick, S, Ron, D. Deposit date: 2021-03-24 Release date: 2021-09-29 Last modified: 2021-10-20 Method: ELECTRON MICROSCOPY (3.96 Å) Cite: Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
2A3Z	Ternary complex of the WH2 domain of WASP with Actin-DNAse I Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... Authors: Chereau, D, Kerff, F, Dominguez, R. Deposit date: 2005-06-27 Release date: 2005-11-01 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.078 Å) Cite: Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly Proc.Natl.Acad.Sci.Usa, 102, 2005

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