PDB: 61 resultsInfo pagesStatus searchChemie searchBIRD

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6EPC	Ground state 26S proteasome (GS2) Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... Authors: Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. Deposit date: 2017-10-11 Release date: 2018-02-07 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (12.3 Å) Cite: In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
6EPD	Substrate processing state 26S proteasome (SPS1) Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... Authors: Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. Deposit date: 2017-10-11 Release date: 2018-02-07 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (15.4 Å) Cite: In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
6EPE	Substrate processing state 26S proteasome (SPS2) Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... Authors: Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. Deposit date: 2017-10-11 Release date: 2018-02-07 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (12.8 Å) Cite: In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
6EPF	Ground state 26S proteasome (GS1) Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... Authors: Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. Deposit date: 2017-10-11 Release date: 2018-02-07 Last modified: 2019-12-11 Method: ELECTRON MICROSCOPY (11.8 Å) Cite: In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
6MSB	Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Mao, Y.D. Deposit date: 2018-10-16 Release date: 2018-12-05 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3 Å) Cite: Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
6MSD	Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Mao, Y.D. Deposit date: 2018-10-16 Release date: 2018-12-05 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
6MSE	Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Mao, Y.D. Deposit date: 2018-10-16 Release date: 2018-11-21 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
6MSG	Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Mao, Y.D. Deposit date: 2018-10-16 Release date: 2018-11-21 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
6MSH	Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Mao, Y.D. Deposit date: 2018-10-16 Release date: 2018-11-21 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
6MSJ	Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Mao, Y.D. Deposit date: 2018-10-16 Release date: 2018-11-21 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
6MSK	Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Mao, Y.D. Deposit date: 2018-10-16 Release date: 2018-11-21 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome. Nature, 565, 2019
6MUN	Structure of hRpn10 bound to UBQLN2 UBL Descriptor: 26S proteasome non-ATPase regulatory subunit 4, Ubiquilin-2 Authors: Chen, X, Walters, K.J. Deposit date: 2018-10-23 Release date: 2019-09-04 Last modified: 2019-12-04 Method: SOLUTION NMR Cite: Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome. J.Mol.Biol., 431, 2019
6NJG	Ubiquitin Variant in Complex with Ubiquitin Interacting Motif Descriptor: Polyubiquitin-B, Vacuolar protein sorting-associated protein 27 Authors: Manczyk, N, Sicheri, F. Deposit date: 2019-01-03 Release date: 2019-03-06 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif. Protein Sci., 28, 2019
6WJD	SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ... Authors: Chen, X, Walters, K.J. Deposit date: 2020-04-13 Release date: 2020-08-05 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome. Structure, 28, 2020
7QXN	Proteasome-ZFAND5 Complex Z+A state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-26 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QXP	Proteasome-ZFAND5 Complex Z+B state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-26 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QXU	Proteasome-ZFAND5 Complex Z+C state Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QXW	Proteasome-ZFAND5 Complex Z+D state Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QXX	Proteasome-ZFAND5 Complex Z+E state Descriptor: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QY7	Proteasome-ZFAND5 Complex Z-A state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QYA	Proteasome-ZFAND5 Complex Z-B state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7QYB	Proteasome-ZFAND5 Complex Z-C state Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhu, Y, Lu, Y. Deposit date: 2022-01-27 Release date: 2023-02-08 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5 To Be Published
7W37	Structure of USP14-bound human 26S proteasome in state EA1_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W38	Structure of USP14-bound human 26S proteasome in state EA2.0_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W39	Structure of USP14-bound human 26S proteasome in state EA2.1_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2022-06-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022

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