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5MOM	Crystal Structure of PCNA encoding the hypomorphic mutation S228I Descriptor: Proliferating cell nuclear antigen Authors: Biasutto, A.J, Mancini, E.J, Green, C.M, Wilson, R.H.C. Deposit date: 2016-12-14 Release date: 2017-01-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.27 Å) Cite: PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair (Amst.), 50, 2017
5MLW	Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide Descriptor: APIM motif peptide, Proliferating cell nuclear antigen, SULFATE ION Authors: Ariza, A. Deposit date: 2016-12-07 Release date: 2017-06-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017
5MLO	Crystal structure of human PCNA in complex with ZRANB3 PIP box peptide Descriptor: Proliferating cell nuclear antigen, SODIUM ION, ZRANB3 PIP box peptide Authors: Ariza, A. Deposit date: 2016-12-07 Release date: 2017-06-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017
5MAV	Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide. Descriptor: Poly (ADP-ribose) glycohydrolase, Proliferating cell nuclear antigen Authors: Grishkovskaya, I, Djinovic-Carugo, K, Slade, D. Deposit date: 2016-11-06 Release date: 2017-08-02 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.575 Å) Cite: A novel non-canonical PIP-box mediates PARG interaction with PCNA. Nucleic Acids Res., 45, 2017
5H0T	Crystal structure of proliferating cell nuclear antigen from Leishmania donovani at 2.73 Angstrom resolution Descriptor: DI(HYDROXYETHYL)ETHER, Proliferating cell nuclear antigen Authors: Singh, P.K, Yadav, S.P, Sharma, P.S, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2016-10-06 Release date: 2016-11-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.73 Å) Cite: Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani. Biochim. Biophys. Acta, 1865, 2017
5T9D	Structure of PCNA acetylated on K20 Descriptor: Proliferating cell nuclear antigen Authors: Couture, J.F, Tremblay, V, Brunzelle, J.S. Deposit date: 2016-09-09 Release date: 2017-04-05 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.27 Å) Cite: Structure of PCNA acetylated on K20 To Be Published
5JNE	E2-SUMO-Siz1 E3-SUMO-PCNA complex Descriptor: E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ... Authors: Lima, C.D, Streich Jr, F.C. Deposit date: 2016-04-29 Release date: 2016-08-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Capturing a substrate in an activated RING E3/E2-SUMO complex. Nature, 536, 2016
5IY4	Crystal structure of human PCNA in complex with the PIP box of DVC1 Descriptor: DVC1 PIP box, Proliferating cell nuclear antigen Authors: Jiang, T, Xu, M, Wang, Y. Deposit date: 2016-03-24 Release date: 2016-06-08 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.945 Å) Cite: Crystal structure of human PCNA in complex with the PIP box of DVC1 Biochem.Biophys.Res.Commun., 474, 2016
5HAC	Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution Descriptor: Proliferating cell nuclear antigen Authors: Singh, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2015-12-30 Release date: 2016-03-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution To Be Published
5E0T	Human PCNA mutant - S228I Descriptor: Proliferating cell nuclear antigen Authors: Duffy, C.M, Hilbert, B.J, Kelch, B.A. Deposit date: 2015-09-29 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6653 Å) Cite: A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
5E0V	Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms Descriptor: Flap endonuclease 1, Proliferating cell nuclear antigen Authors: Duffy, C.M, Hilbert, B.J, Kelch, B.A. Deposit date: 2015-09-29 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.074 Å) Cite: A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
5E0U	Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen Authors: Duffy, C.M, Hilbert, B.J, Kelch, B.A. Deposit date: 2015-09-29 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.93 Å) Cite: A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
5DAI	Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide Descriptor: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION Authors: Ladner, J.E, Altieri, A.S, Kelman, Z. Deposit date: 2015-08-20 Release date: 2016-05-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
5DA7	monomeric PCNA bound to a small protein inhibitor Descriptor: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ... Authors: Ladner, J.E, Altieri, A.S, Kelman, Z. Deposit date: 2015-08-19 Release date: 2016-05-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.802 Å) Cite: A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
5CFK	Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution Descriptor: Proliferating cell nuclear antigen,Proliferating cell nuclear antigen Authors: Shukla, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2015-07-08 Release date: 2015-10-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution To Be Published
5A6D	Proliferating Cell Nuclear Antigen, PCNA, from Thermococcus gammatolerans Descriptor: DNA POLYMERASE SLIDING CLAMP Authors: Venancio-Landeros, A, Cardona-Felix, C.S, Rudino-Pinera, E. Deposit date: 2015-06-25 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans. Biochem Biophys Rep, 8, 2016
3JA9	Structure of native human PCNA Descriptor: Proliferating cell nuclear antigen Authors: Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y. Deposit date: 2015-05-19 Release date: 2015-12-09 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (22 Å) Cite: Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA Sci Rep, 5, 2015
4ZTD	Crystal Structure of Human PCNA in complex with a TRAIP peptide Descriptor: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen Authors: Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A. Deposit date: 2015-05-14 Release date: 2015-12-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.199 Å) Cite: TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J.Cell Biol., 212, 2016
5AUJ	Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative Descriptor: DNA polymerase sliding clamp Authors: Watanabe, Y, Oyama, T. Deposit date: 2015-04-21 Release date: 2016-04-27 Last modified: 2020-02-19 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative To Be Published
4YHR	Crystal Structure of Yeast Proliferating Cell Nuclear Antigen Descriptor: Proliferating cell nuclear antigen Authors: Litman, J.M, Nguyen, V.Q, Kondratick, C.M, Powers, K.T, Schnieders, M.J, Washington, M.T. Deposit date: 2015-02-27 Release date: 2015-03-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.9502 Å) Cite: Dead-End Elimination with a Polarizable Force Field Repacks PCNA Models from Low-Resolution X-ray Diffraction into Atomic Resolution Structures To be published
4RJF	Crystal structure of the human sliding clamp at 2.0 angstrom resolution Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen Authors: Kroker, A.J, Bruning, J.B. Deposit date: 2014-10-09 Release date: 2015-08-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.0072 Å) Cite: p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding. Biochemistry, 54, 2015
4D2G	Crystal structure of human PCNA in complex with p15 peptide Descriptor: P15, PROLIFERATING CELL NUCLEAR ANTIGEN Authors: DeBiasio, A, Ibanez, A, Mortuza, G, Molina, R, Cordeiro, T.N, Castillo, F, Villate, M, Merino, N, Lelli, M, Diercks, T, Luque, I, Bernardo, P, Montoya, G, Blanco, F.J. Deposit date: 2014-05-09 Release date: 2015-03-18 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair. Nat.Commun., 6, 2015
4CS5	Crystal Structure of PCNA from Litopenaeus vannamei Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN Authors: Carrasco-Miranda, J.S, Lopez-Zavala, A.A, De-La-Mora, E, Rudino-Pinera, E, Brieba, L.G, Sotelo-Mundo, R.R. Deposit date: 2014-03-04 Release date: 2014-04-23 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with Wssv DNA Polymerase Pip-Box. Plos One, 9, 2014
3WGW	Structure of PCNA bound to a small molecule inhibitor Descriptor: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION Authors: Hashimoto, H. Deposit date: 2013-08-12 Release date: 2014-02-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.8 Å) Cite: A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin. J.Biol.Chem., 289, 2014
4L6P	Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair Descriptor: GLYCEROL, Proliferating cell nuclear antigen Authors: Washington, T, Boehm, E. Deposit date: 2013-06-12 Release date: 2014-10-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair. Biochemistry, 52, 2013

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