1L6F
 
 | | Alanine racemase bound with N-(5'-phosphopyridoxyl)-L-alanine | | Descriptor: | ALANYL-PYRIDOXAL-5'-PHOSPHATE, alanine racemase | | Authors: | Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N. | | Deposit date: | 2002-03-09 | | Release date: | 2002-06-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
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7XLL
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3KW3
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4QHR
 | | The structure of alanine racemase from Acinetobacter baumannii | | Descriptor: | Alanine racemase | | Authors: | Davis, E, Scaletti-Hutchinson, E, Nakatani, Y, Krause, K.L. | | Deposit date: | 2014-05-29 | | Release date: | 2015-05-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The structure of alanine racemase from Acinetobacter baumannii
ACTA CRYSTALLOGR.,SECT.F, 70, 2014
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6SCZ
 | | Mycobacterium tuberculosis alanine racemase inhibited by DCS | | Descriptor: | (~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | Authors: | de Chiara, C, Purkiss, A, Prosser, G, Homsak, M, de Carvalho, L.P.S. | | Deposit date: | 2019-07-26 | | Release date: | 2020-04-01 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | D-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition.
Nat.Chem.Biol., 16, 2020
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1BD0
 | | ALANINE RACEMASE COMPLEXED WITH ALANINE PHOSPHONATE | | Descriptor: | ALANINE RACEMASE, {1-[(3-HYDROXY-METHYL-5-PHOSPHONOOXY-METHYL-PYRIDIN-4-YLMETHYL)-AMINO]-ETHYL}-PHOSPHONIC ACID | | Authors: | Stamper, G.F, Morollo, A.A, Ringe, D. | | Deposit date: | 1998-05-12 | | Release date: | 1998-10-14 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Reaction of alanine racemase with 1-aminoethylphosphonic acid forms a stable external aldimine.
Biochemistry, 37, 1998
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7AGZ
 | | BsrV no-histagged | | Descriptor: | Broad specificity amino-acid racemase, CHLORIDE ION, GLYCEROL, ... | | Authors: | Carrasco-Lopez, C, Rojas-Altuve, A, Espaillat, A, Cava, F, Hermoso, J.A. | | Deposit date: | 2020-09-23 | | Release date: | 2021-10-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Binding of non-canonical peptidoglycan controls Vibrio cholerae broad spectrum racemase activity.
Comput Struct Biotechnol J, 19, 2021
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3UW6
 | | Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR120 | | Descriptor: | Alanine racemase | | Authors: | Seetharaman, J, Lew, S, Nivon, L, Baker, D, Bjelic, S, Ciccosanti, C, Sahdev, S, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-11-30 | | Release date: | 2012-02-08 | | Last modified: | 2022-03-02 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Computational design of enone-binding proteins with catalytic activity for the Morita-Baylis-Hillman reaction.
Acs Chem.Biol., 8, 2013
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2ODO
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5IRP
 | | Crystal structure of the alanine racemase Bsu17640 from Bacillus subtilis | | Descriptor: | (5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alanine racemase 2, ... | | Authors: | Bernardo-Garcia, N, Gago, F, Hermoso, J.A. | | Deposit date: | 2016-03-14 | | Release date: | 2017-03-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Cold-induced aldimine bond cleavage by Tris in Bacillus subtilis alanine racemase.
Org.Biomol.Chem., 17, 2019
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1NIU
 | | ALANINE RACEMASE WITH BOUND INHIBITOR DERIVED FROM L-CYCLOSERINE | | Descriptor: | Alanine Racemase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | | Authors: | Fenn, T.D, Stamper, G.F, Morollo, A.A, Ringe, D. | | Deposit date: | 2002-12-26 | | Release date: | 2003-09-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A side reaction of alanine racemase: transamination of cycloserine.
Biochemistry, 42, 2003
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2DY3
 | | Crystal Structure of alanine racemase from Corynebacterium glutamicum | | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Miyaguchi, I, Sasaki, C, Kato, R, Oikawa, T, Sugio, S. | | Deposit date: | 2006-09-05 | | Release date: | 2007-09-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of Alanine Racemase from Corynebacterium glutamicum at 2.1 A resolution
To be Published
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1L6G
 | | Alanine racemase bound with N-(5'-phosphopyridoxyl)-D-alanine | | Descriptor: | N-(5'-PHOSPHOPYRIDOXYL)-D-ALANINE, alanine racemase | | Authors: | Watanabe, A, Yoshimura, T, Mikami, B, Hayashi, H, Kagamiyama, H, Esaki, N. | | Deposit date: | 2002-03-10 | | Release date: | 2002-06-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J.Biol.Chem., 277, 2002
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5ZL6
 | | Histidine Racemase from Leuconostoc mesenteroides subsp. sake NBRC 102480 | | Descriptor: | Histidine racemase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Adachi, M, Shimizu, R, Oikawa, T. | | Deposit date: | 2018-03-27 | | Release date: | 2018-11-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The first identification and characterization of a histidine-specific amino acid racemase, histidine racemase from a lactic acid bacterium, Leuconostoc mesenteroides subsp. sake NBRC 102480.
Amino Acids, 51, 2019
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5YYC
 | | Crystal structure of alanine racemase from Bacillus pseudofirmus (OF4) | | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Dong, H, Hu, T.T, He, G.Z, Lu, D.R, Qi, J.X, Dou, Y.S, Long, W, He, X, Su, D, Ju, J.S. | | Deposit date: | 2017-12-08 | | Release date: | 2019-01-02 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | Structural features and kinetic characterization of alanine racemase from Bacillus pseudofirmus OF4.
Biochem. Biophys. Res. Commun., 497, 2018
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1VFH
 | | Crystal structure of alanine racemase from D-cycloserine producing Streptomyces lavendulae | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, alanine racemase | | Authors: | Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M. | | Deposit date: | 2004-04-13 | | Release date: | 2004-09-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
J.Biol.Chem., 279, 2004
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4FS9
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1VFS
 | | Crystal structure of D-cycloserine-bound form of alanine racemase from D-cycloserine-producing Streptomyces lavendulae | | Descriptor: | CHLORIDE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, alanine racemase | | Authors: | Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M. | | Deposit date: | 2004-04-19 | | Release date: | 2004-09-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.
J.Biol.Chem., 279, 2004
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8AHW
 | | Structure of DCS-resistant variant D322N of alanine racemase from Mycobacterium tuberculosis | | Descriptor: | 1,2-ETHANEDIOL, Alanine racemase, GLYCEROL | | Authors: | de Chiara, C, Prosser, G, Ogrodowicz, R.W, de Carvalho, L.P.S. | | Deposit date: | 2022-07-22 | | Release date: | 2023-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis .
Acs Bio Med Chem Au, 3, 2023
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8B8H
 | | Structure of DCS-resistant variant D322N of alanine racemase from M. tuberculosis in complex with DCS | | Descriptor: | (~{E})-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylidene-[(4~{R})-3-oxidanylidene-1,2-oxazolidin-4-yl]azanium, 1,2-ETHANEDIOL, Alanine racemase, ... | | Authors: | de Chiara, C, Prosser, G, Ogrodowicz, R.W, de Carvalho, L.P.S. | | Deposit date: | 2022-10-04 | | Release date: | 2023-04-05 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis .
Acs Bio Med Chem Au, 3, 2023
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6A2F
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3HA1
 | | Alanine racemase from Bacillus Anthracis (Ames) | | Descriptor: | ACETATE ION, Alanine racemase, CHLORIDE ION | | Authors: | Counago, R.M, Davlieva, M, Strych, U, Hill, R.E, Krause, K.L. | | Deposit date: | 2009-04-30 | | Release date: | 2009-09-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames).
Bmc Struct.Biol., 9, 2009
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1RCQ
 | | The 1.45 A crystal structure of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms | | Descriptor: | D-LYSINE, PYRIDOXAL-5'-PHOSPHATE, catabolic alanine racemase DadX | | Authors: | Le Magueres, P, Im, H, Dvorak, A, Strych, U, Benedik, M, Krause, K.L. | | Deposit date: | 2003-11-04 | | Release date: | 2004-06-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms.
Biochemistry, 42, 2003
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3HUR
 | | Crystal structure of alanine racemase from Oenococcus oeni | | Descriptor: | Alanine racemase, SULFATE ION | | Authors: | Bonanno, J.B, Rutter, M, Bain, K.T, Hu, S, Romero, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2009-06-15 | | Release date: | 2009-07-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of alanine racemase from Oenococcus oeni
To be Published
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3S46
 | | The crystal structure of alanine racemase from streptococcus pneumoniae | | Descriptor: | Alanine racemase, BENZOIC ACID | | Authors: | Im, H, Sharpe, M.L, Strych, U, Davlieva, M, Krause, K.L. | | Deposit date: | 2011-05-18 | | Release date: | 2011-06-22 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design.
BMC MICROBIOL., 11, 2011
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