6SCZ

Mycobacterium tuberculosis alanine racemase inhibited by DCS

Summary for 6SCZ

Entry DOI	10.2210/pdb6scz/pdb
Descriptor	Alanine racemase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... (11 entities in total)
Functional Keywords	enzyme, alanine racemase, peptidoglycan biosynthesis, isomerase
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	2
Total formula weight	89556.16
Authors	de Chiara, C.,Purkiss, A.,Prosser, G.,Homsak, M.,de Carvalho, L.P.S. (deposition date: 2019-07-26, release date: 2020-04-01, Last modification date: 2024-01-24)
Primary citation	de Chiara, C.,Homsak, M.,Prosser, G.A.,Douglas, H.L.,Garza-Garcia, A.,Kelly, G.,Purkiss, A.G.,Tate, E.W.,de Carvalho, L.P.S. D-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition. Nat.Chem.Biol., 16:686-694, 2020 Cited by PubMed: 32203411 DOI: 10.1038/s41589-020-0498-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.57 Å)

Structure validation