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6VVH	Arabidopsis thaliana dihydrodipicolinate synthase isoform 1 (DHDPS1) in complex with lysine Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, ... Authors: Lee, M, Hall, C.J. Deposit date: 2020-02-18 Release date: 2021-02-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.792 Å) Cite: Differential lysine-mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms. Febs J., 288, 2021
5CZJ	Crystal structure of HypD, a 1-pyrroline-4-hydroxy-2-carboxylate deaminase from Sinorhizobium meliloti Descriptor: Dihydrodipicolinate synthase Authors: Stogios, P.J, Xu, X, Savchenko, A. Deposit date: 2015-07-31 Release date: 2016-02-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.92 Å) Cite: l-Hydroxyproline and d-Proline Catabolism in Sinorhizobium meliloti. J.Bacteriol., 198, 2016
4EOU	Crystal structure of E. coli dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site Descriptor: Dihydrodipicolinate synthase, GLYCEROL, POTASSIUM ION Authors: Boughton, B.A, Dobson, R.C.J, Hutton, C.A. Deposit date: 2012-04-15 Release date: 2012-04-25 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: Unambiguous resolution of the stereochemistry of the condensation product. Proteins, 80, 2012
4O0K	Crystal structure of 1-pyrroline-4-hydroxy-2-carboxylate deaminase from Brucella melitensis with covalently bound substrate Descriptor: 1,2-ETHANEDIOL, Dihydrodipicolinate synthetase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-12-13 Release date: 2014-01-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of 1-pyrroline-4-hydroxy-2-carboxylate deaminase from Brucella melitensis with covalently bound substrate To be Published
8GEK	Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase Authors: Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J. Deposit date: 2023-03-06 Release date: 2024-03-20 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum To Be Published
7M06	Dihydrodipicolinate synthase (DHDPS) from C.jejuni, Y110F mutant with R,R-bislysine bound at the allosteric site at 2.7 Angstrom Descriptor: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... Authors: Saran, S, Sanders, D.A.R. Deposit date: 2021-03-10 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.7 Å) Cite: B-FACTOR ANALYSIS SUGGEST THAT L-LYSINE AND R, R-BISLYSINE ALLOSTERICALLY INHIBIT Cj.DHDPS ENZYME BY DECREASING PROTEIN DYNAMICS To Be Published
3L21	The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (DAPA, RV2753C) from Mycobacterium Tuberculosis - DHDPS-A204R Descriptor: ACETATE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... Authors: Evans, G.L, Schuldt, L, Jamerson, G.B, Devenish, S.R, Weiss, M.S, Gerrard, J.A. Deposit date: 2009-12-14 Release date: 2010-12-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A dimeric mutant of DHDPS from Mycobacterium tuberculosis To be Published
1HL2	Crystal structure of N-acetylneuraminate lyase from E. coli mutant L142R in complex with b-hydroxypyruvate Descriptor: 3-HYDROXYPYRUVIC ACID, N-ACETYLNEURAMINATE LYASE SUBUNIT Authors: Joerger, A.C, Fersht, A.R. Deposit date: 2003-03-12 Release date: 2003-05-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Mimicking Natural Evolution in Vitro: An N-Acetylneuraminate Lyase Mutant with an Increased Dihydrodipicolinate Synthase Activity Proc.Natl.Acad.Sci.USA, 100, 2003
2HMC	The Crystal Structure of Dihydrodipicolinate Synthase DapA from Agrobacterium tumefaciens Descriptor: Dihydrodipicolinate synthase, MAGNESIUM ION Authors: Kim, Y, Zhang, R, Xu, X, Zheng, H, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) Deposit date: 2006-07-11 Release date: 2006-09-05 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The Crystal Structure of Dihydrodipicolinate Synthase DapA from Agrobacterium tumefaciens To be Published, 2006
6XGS	Crystal Structure of Dihydrodipicolinate synthase (DHDPS) from Brucella suis 1330 Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, CITRIC ACID, PHOSPHATE ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2020-06-18 Release date: 2020-07-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of Dihydrodipicolinate synthase (DHDPS) from Brucella suis 1330 to be published
8DO5	Crystal structure of NahE in complex with intermediate (R)-4-hydroxy-4-(2-hydroxyphenyl)-2-iminobutanoate Descriptor: (4R)-4-hydroxy-4-(2-hydroxyphenyl)butanoic acid, DIMETHYL SULFOXIDE, Trans-ohydrobenzylidenepyruvate hydratase aldolase Authors: LeVieux, J.A, Hardtke, H.A, Zhang, Y.J. Deposit date: 2022-07-12 Release date: 2022-12-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A mutagenic analysis of NahE, a hydratase-aldolase in the naphthalene degradative pathway. Arch.Biochem.Biophys., 733, 2023
6MQH	Crystal structure of 4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) from Burkholderia mallei Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-10-09 Release date: 2018-10-31 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of 4-hydroxy-tetrahydrodipicolinate synthase (HTPA synthase) from Burkholderia mallei To be Published
7C0D	Crystal structure of Azospirillum brasilense L-2-keto-3-deoxyarabonate dehydratase (Hydroxypyruvate-bound form) Descriptor: L-2-keto-3-deoxyarabonate dehydratase Authors: Watanabe, Y, Watanabe, S. Deposit date: 2020-05-01 Release date: 2020-08-05 Last modified: 2020-09-02 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Biochemical and Structural Characterization of l-2-Keto-3-deoxyarabinonate Dehydratase: A Unique Catalytic Mechanism in the Class I Aldolase Protein Superfamily. Biochemistry, 59, 2020
6ARH	Crystal structure of Human NAL at a resolution of 1.6 Angstrom Descriptor: ACETATE ION, N-acetylneuraminate lyase Authors: Pearce, F.G, Bundela, R, Keown, J.R. Deposit date: 2017-08-22 Release date: 2018-08-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of Human NAL at a resolution of 1.6 Angstrom To Be Published
6NVA	Crystal structure of Escherichia coli dihydrodipicolinate synthase and propionate covalently bound to K161. Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, SODIUM ION Authors: Thomas, L.M, Chooback, L. Deposit date: 2019-02-04 Release date: 2019-02-27 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Crystal structure of Escherichia coli dihydrodipicolinate synthase and propionate covalently bound to K161. To Be Published
3TCE	Crystal structure of the complex of Dihydrodipicolinate synthase from Acinetobacter baumannii with 5-Hydroxylysine at 2.6 A resolution Descriptor: 5-HYDROXYLYSINE, Dihydrodipicolinate synthase Authors: Shukla, P.K, Kaushik, S, Sinha, M, Kaur, P, Tewari, R, Sharma, S, Singh, T.P. Deposit date: 2011-08-09 Release date: 2011-08-31 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structure of the complex of Dihydrodipicolinate synthase from Acinetobacter baumannii with 5-Hydroxylysine at 2.6 A resolution To be Published
7C0E	Crystal structure of Azospirillum brasilense L-2-keto-3-deoxyarabonate dehydratase (2-oxobutyrate-bound form) Descriptor: L-2-keto-3-deoxyarabonate dehydratase Authors: Watanabe, Y, Ono, A, Watanabe, S. Deposit date: 2020-05-01 Release date: 2020-08-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.204 Å) Cite: Biochemical and Structural Characterization of l-2-Keto-3-deoxyarabinonate Dehydratase: A Unique Catalytic Mechanism in the Class I Aldolase Protein Superfamily. Biochemistry, 59, 2020
7C0C	Crystal structure of Azospirillum brasilense L-2-keto-3-deoxyarabonate dehydratase (apo form) Descriptor: L-2-keto-3-deoxyarabonate dehydratase Authors: Watanabe, Y, Nobuchi, R, Watanabe, S. Deposit date: 2020-05-01 Release date: 2020-08-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Biochemical and Structural Characterization of l-2-Keto-3-deoxyarabinonate Dehydratase: A Unique Catalytic Mechanism in the Class I Aldolase Protein Superfamily. Biochemistry, 59, 2020
4U4M	Crystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with Pyruvate Descriptor: 1,2-ETHANEDIOL, PYRUVIC ACID, UREA, ... Authors: Manoj Kumar, P, Bhaskar, V, Manicka, S, Krishnaswamy, S. Deposit date: 2014-07-24 Release date: 2015-07-29 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Crystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with Pyruvate To be published
3U8G	Crystal structure of the complex of Dihydrodipicolinate synthase from Acinetobacter baumannii with Oxalic acid at 1.80 A resolution Descriptor: Dihydrodipicolinate synthase, OXALATE ION Authors: Kumar, M, Kaushik, S, Bhushan, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2011-10-17 Release date: 2011-11-02 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the complex of Dihydrodipicolinate synthase from Acinetobacter baumannii with Oxalic acid at 1.80 A resolution To be Published
5F1U	biomimetic design results in a potent allosteric inhibitor of dihydrodipicolinate synthase from Campylobacter jejuni Descriptor: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... Authors: Conly, C.J.T, Palmer, D.R.J, Sanders, D.A.R. Deposit date: 2015-11-30 Release date: 2016-02-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni. J.Am.Chem.Soc., 138, 2016
4UR8	Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid Descriptor: 2-OXOADIPIC ACID, FORMIC ACID, KETO-DEOXY-D-GALACTARATE DEHYDRATASE Authors: Taberman, H, Parkkinen, T, Hakulinen, N, Rouvinen, J. Deposit date: 2014-06-26 Release date: 2014-12-17 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.097 Å) Cite: Structure and Function of a Decarboxylating Agrobacterium Tumefaciens Keto-Deoxy-D-Galactarate Dehydratase. Biochemistry, 53, 2014
1O5K	Crystal structure of Dihydrodipicolinate synthase (TM1521) from Thermotoga maritima at 1.80 A resolution Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, CALCIUM ION Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2003-09-22 Release date: 2003-10-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of Dihydrodipicolinate synthase (TM1521) from Thermotoga maritima at 1.80 A resolution To be published
5F1V	biomimetic design results in a potent allosteric inhibitor of dihydrodipicolinate synthase from Campylobacter jejuni Descriptor: (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid, 1,2-ETHANEDIOL, 4-hydroxy-tetrahydrodipicolinate synthase, ... Authors: Conly, C.J.T, Palmer, D.R.J, Sanders, D.A.R. Deposit date: 2015-11-30 Release date: 2016-02-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni. J.Am.Chem.Soc., 138, 2016
7MJF	Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site Descriptor: (4R)-4-oxidanyl-2-oxidanylidene-heptanedioic acid, (4S)-4-hydroxy-2-oxoheptanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase Authors: Gilkes, J, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J. Deposit date: 2021-04-20 Release date: 2021-07-14 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site To Be Published

 

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