1A7U
| CHLOROPEROXIDASE T | Descriptor: | CHLOROPEROXIDASE T | Authors: | Hofmann, B, Toelzer, S, Pelletier, I, Altenbuchner, J, Van Pee, K.-H, Hecht, H.-J. | Deposit date: | 1998-03-17 | Release date: | 1998-06-17 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural investigation of the cofactor-free chloroperoxidases. J.Mol.Biol., 279, 1998
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4LIP
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5C7Y
| ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 9min | Descriptor: | (1E,10S)-1-(3,5-dihydroxyphenyl)-10-hydroxyundec-1-en-6-one, FORMIC ACID, GLYCEROL, ... | Authors: | Hu, X.-J, Qi, Q, Yang, W.-J. | Deposit date: | 2015-06-25 | Release date: | 2016-06-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A Case Study of Lactonase ZHD To Be Published
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7YAS
| HYDROXYNITRILE LYASE, LOW TEMPERATURE NATIVE STRUCTURE | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, PROTEIN (HYDROXYNITRILE LYASE), ... | Authors: | Zuegg, J, Wagner, U.G, Gugganig, M, Kratky, C. | Deposit date: | 1999-03-15 | Release date: | 1999-10-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis. Protein Sci., 8, 1999
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7O8B
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2OCG
| Crystal structure of human valacyclovir hydrolase | Descriptor: | GLYCEROL, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Lai, L, Xu, Z, Amidon, G.L. | Deposit date: | 2006-12-20 | Release date: | 2008-02-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase. J.Biol.Chem., 283, 2008
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4H7K
| Crystal structure of haloalkane dehalogenase LinB I253M mutant from Sphingobium sp. MI1205 | Descriptor: | CALCIUM ION, CHLORIDE ION, Haloalkane dehalogenase | Authors: | Okai, M, Ohtsuka, J, Imai, L.F, Mase, T, Moriuchi, R, Tsuda, M, Nagata, K, Nagata, Y, Tanokura, M. | Deposit date: | 2012-09-20 | Release date: | 2013-06-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure and Site-Directed Mutagenesis Analyses of Haloalkane Dehalogenase LinB from Sphingobium sp. Strain MI1205. J.Bacteriol., 195, 2013
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7A42
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7A43
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4CCW
| Crystal structure of naproxen esterase (carboxylesterase NP) from Bacillus subtilis | Descriptor: | (2-hydroxyethoxy)acetic acid, CARBOXYL ESTERASE NP | Authors: | Rozeboom, H.J, Godinho, L.F, Nardini, M, Quax, W.J, Dijkstra, B.W. | Deposit date: | 2013-10-29 | Release date: | 2014-01-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structures of Two Bacillus Carboxylesterases with Different Enantioselectivities. Biochim.Biophys.Acta, 1844, 2014
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4NZZ
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5AI0
| Ligand complex structure of soluble epoxide hydrolase | Descriptor: | 4-PHENYL-1,2,5-OXADIAZOL-3-AMINE, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, ... | Authors: | Oster, L, Tapani, S, Xue, Y, Kack, H. | Deposit date: | 2015-02-11 | Release date: | 2015-05-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
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1YB7
| Hydroxynitrile lyase from hevea brasiliensis in complex with 2,3-dimethyl-2-hydroxy-butyronitrile | Descriptor: | (S)-2-HYDROXY-2,3-DIMETHYLBUTANENITRILE, (S)-acetone-cyanohydrin lyase, SULFATE ION | Authors: | Gruber, K, Gartler, G, Kratky, C. | Deposit date: | 2004-12-20 | Release date: | 2005-12-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural determinants of the enantioselectivity of the hydroxynitrile lyase from Hevea brasiliensis J.Biotechnol., 129, 2007
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4BB0
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3QYJ
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3A2L
| Crystal structure of DBJA (mutant dbja delta) | Descriptor: | CHLORIDE ION, GLYCEROL, Haloalkane dehalogenase, ... | Authors: | Sato, Y, Senda, T. | Deposit date: | 2009-05-23 | Release date: | 2010-05-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering Angew.Chem.Int.Ed.Engl., 49, 2010
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3SK0
| structure of Rhodococcus rhodochrous haloalkane dehalogenase DhaA mutant DhaA12 | Descriptor: | CHLORIDE ION, Haloalkane dehalogenase | Authors: | Lahoda, M, Stsiapanava, A, Mesters, J, Koudelakova, T, Damborsky, J, Kuta-Smatanova, I. | Deposit date: | 2011-06-22 | Release date: | 2012-06-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Dynamics and hydration explain failed functional transformation in dehalogenase design. Nat.Chem.Biol., 10, 2014
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6KXH
| Alp1U_Y247F mutant in complex with Fluostatin C | Descriptor: | D-MALATE, Fluostatin C, Putative hydrolase, ... | Authors: | Zhang, L, Yingli, Z, De, B.C, Zhang, C. | Deposit date: | 2019-09-11 | Release date: | 2020-09-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.78039551 Å) | Cite: | Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the alpha / beta-fold epoxide hydrolase Alp1U. J.Biol.Chem., 295, 2020
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5AK4
| ligand complex structure of soluble epoxide hydrolase | Descriptor: | 3-METHYL-4-PHENYL-1H-PYRAZOLE, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE | Authors: | Oster, L, Tapani, S, Xue, Y, Kack, H. | Deposit date: | 2015-03-02 | Release date: | 2015-05-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
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2PSH
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7OTS
| Crystal structure of human Monoacylglycerol Lipase ABHD6 in complex with oleic acid and octyl glucoside | Descriptor: | GLYCEROL, Monoacylglycerol lipase ABHD6, OLEIC ACID, ... | Authors: | Nawrotek, A, Talagas, A, Vuillard, L, Miallau, L. | Deposit date: | 2021-06-10 | Release date: | 2021-06-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.792 Å) | Cite: | Crystal structure of human Monoacylglycerol Lipase ABHD6 in complex with oleic acid and octyl glucoside To Be Published
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6QHZ
| Time resolved structural analysis of the full turnover of an enzyme - 6788 ms | Descriptor: | Fluoroacetate dehalogenase, fluoroacetic acid | Authors: | Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D. | Deposit date: | 2019-01-17 | Release date: | 2019-09-25 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Time-resolved crystallography reveals allosteric communication aligned with molecular breathing. Science, 365, 2019
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6COD
| AtHNL enantioselectivity mutant At-A9-H7 Apo Y13C,Y121L,P126F,L128W,C131T,F179L,A209I with benzaldehyde | Descriptor: | Alpha-hydroxynitrile lyase, CHLORIDE ION, GLYCEROL, ... | Authors: | Jones, B.J, Kazlauskas, R.J, Desrouleaux, R. | Deposit date: | 2018-03-12 | Release date: | 2019-03-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | AtHNL enantioselectivity mutants To be published
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6MUH
| Fluoroacetate dehalogenase, room temperature structure solved by serial 1 degree oscillation crystallography | Descriptor: | Fluoroacetate dehalogenase | Authors: | Finke, A.D, Wierman, J.L, Pare-Labrosse, O, Sarrachini, A, Besaw, J, Mehrabi, P, Gruner, S.M, Miller, R.J.D. | Deposit date: | 2018-10-23 | Release date: | 2019-03-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fixed-target serial oscillation crystallography at room temperature. IUCrJ, 6, 2019
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4X6X
| Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative | Descriptor: | 3-{4-[(1-{[(1s,2R,3S)-2,3-diphenylcyclopropyl]carbamoyl}piperidin-4-yl)oxy]phenyl}propanoic acid, Bifunctional epoxide hydrolase 2 | Authors: | Chiyo, N, Takai, K, Ishii, T. | Deposit date: | 2014-12-09 | Release date: | 2015-04-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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