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6U59	HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13B Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SOSIP.664 gp120,SOSIP.664 gp120, ... Authors: Yang, Y.R, Ward, A.B. Deposit date: 2019-08-27 Release date: 2020-01-29 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.86 Å) Cite: Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits. J.Virol., 94, 2020
6U0N	Asymmetrically open conformational state (Class II) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E51 Fab heavy chain, ... Authors: Yang, Z, Bjorkman, P.J. Deposit date: 2019-08-14 Release date: 2019-12-11 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody. Nat.Struct.Mol.Biol., 26, 2019
6U0L	Asymmetrically open conformational state (Class I) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E51 Fab heavy chain, ... Authors: Yang, Z, Bjorkman, P.J. Deposit date: 2019-08-14 Release date: 2019-12-11 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody. Nat.Struct.Mol.Biol., 26, 2019
6TYB	Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2019-08-08 Release date: 2019-10-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.301 Å) Cite: Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields. Immunity, 51, 2019
6PWU	Structure of full-length, fully glycosylated, non-modified HIV-1 gp160 bound to PG16 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Pan, J, Chen, B, Harrison, S.C. Deposit date: 2019-07-23 Release date: 2020-02-26 Last modified: 2022-03-16 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Cryo-EM Structure of Full-length HIV-1 Env Bound With the Fab of Antibody PG16. J.Mol.Biol., 432, 2020
6PW6	The HIV-1 Envelope Glycoprotein Clone BG505 SOSIP.664 in Complex with Three Copies of the Bovine Broadly Neutralizing Antibody, NC-Cow1, Fragment Antigen Binding Domain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly Neutralizing Antibody NC-Cow1 Heavy Chain, ... Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2019-07-22 Release date: 2020-06-24 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural basis of broad HIV neutralization by a vaccine-induced cow antibody. Sci Adv, 6, 2020
6P9N	CRYSTAL STRUCTURE OF HIV-1 LM/HT CLADE A/E CRF01 GP120 CORE IN COMPLEX WITH (S)-MCG-IV-210. Descriptor: (3S)-N~1~-(2-aminoethyl)-N~3~-(4-chloro-3-fluorophenyl)piperidine-1,3-dicarboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Tolbert, W.D, Sherburn, R, Pazgier, M. Deposit date: 2019-06-10 Release date: 2019-10-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.65 Å) Cite: A New Family of Small-Molecule CD4-Mimetic Compounds Contacts Highly Conserved Aspartic Acid 368 of HIV-1 gp120 and Mediates Antibody-Dependent Cellular Cytotoxicity. J.Virol., 93, 2019
6P8M	Crystal Structure of Antibody P-p3b3 A60C Heavy Chain in Complex with 426c HIV-1 gp120 core G459C Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... Authors: Weidle, C, Pancera, M. Deposit date: 2019-06-07 Release date: 2019-11-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.594 Å) Cite: Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization. Cell Rep, 29, 2019
6P6F	BG505 SOSIP-I53-50NP Descriptor: I53-50A.1NT1, I53-50B.4PT1 Authors: Berndsen, Z.T, Ward, A.B. Deposit date: 2019-06-03 Release date: 2019-06-19 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle. Nat Commun, 10, 2019
6P65	HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2019-05-31 Release date: 2019-11-20 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.94 Å) Cite: Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019
6P62	HIV Env BG505 NFL TD+ in complex with antibody E70 fragment antigen binding Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env BG505 NFL TD+, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2019-05-31 Release date: 2019-11-20 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity, 51, 2019
6OZC	BG505 SOSIP.664 with 2G12 Fab2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 Fab Heavy chain, ... Authors: Cottrell, C.A, Ward, A.B. Deposit date: 2019-05-15 Release date: 2020-05-20 Last modified: 2020-08-19 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions. Structure, 28, 2020
6OZ4	Crystal structure of broadly neutralizing antibody N49P6 Fab in complex with HIV-1 BG505 SOSIP.664 Env trimer ectodomain. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... Authors: Tolbert, W.D, Pazgier, M. Deposit date: 2019-05-15 Release date: 2020-08-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.05 Å) Cite: Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer. Mbio, 2021
6OZ3	Crystal structure of broadly neutralizing antibody N49P9.1 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N49P9.1 antibody Fab heavy chain, N49P9.1 antibody Fab light chain, ... Authors: Tolbert, W.D, Pazgier, M. Deposit date: 2019-05-15 Release date: 2020-08-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Crystal structure of broadly neutralizing antibody N49P9.1 Fab in complex with HIV-1 Clade A/E strain 93TH)57 gp120 core To Be Published
6OZ2	Crystal structure of the broadly neutralizing antibody N49P6 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N49P6 antibody Fab heavy chain, N49P6 antibody Fab light chain, ... Authors: Tolbert, W.D, Pazgier, M. Deposit date: 2019-05-15 Release date: 2020-08-19 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer. Mbio, 2021
6OT1	Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 Descriptor: 0PV-b.01 heavy, 0PV-b.01 light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2019-05-02 Release date: 2019-08-07 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
6OSY	Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 Descriptor: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2019-05-02 Release date: 2019-07-24 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
6ORQ	Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ... Authors: Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. Deposit date: 2019-04-30 Release date: 2019-06-12 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
6ORP	Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ... Authors: Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. Deposit date: 2019-04-30 Release date: 2019-06-12 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
6ORO	Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ... Authors: Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. Deposit date: 2019-04-30 Release date: 2019-06-12 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
6ORN	Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074 Descriptor: 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. Deposit date: 2019-04-30 Release date: 2019-06-12 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (4.05 Å) Cite: Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
6OPQ	CD4- and 17-bound HIV-1 Env B41 SOSIP frozen with LMNG Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2019-04-25 Release date: 2020-10-21 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6OPP	Asymmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2019-04-25 Release date: 2020-10-21 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6OPO	Symmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM Descriptor: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2019-04-25 Release date: 2020-10-21 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6OPN	CD4- and 17-bound HIV-1 Env B41 SOSIP in complex with small molecule GO35 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... Authors: Ozorowski, G, Torres, J.L, Ward, A.B. Deposit date: 2019-04-25 Release date: 2020-10-21 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020

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