6XLC
| Full-length Hsc82 bound to AMPPNP | Descriptor: | ATP-dependent molecular chaperone HSC82, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Liu, Y.X, Sun, M, Myasnikov, A.G, Elnatan, D, Agard, D.A. | Deposit date: | 2020-06-28 | Release date: | 2021-06-30 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Full-length Hsc82 bound to AMPPNP To Be Published
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6XLD
| Full-length Hsc82 in complex with Aha1 CTD in the presence of AMPPNP | Descriptor: | ATP-dependent molecular chaperone HSC82, Hsp90 co-chaperone AHA1, MAGNESIUM ION, ... | Authors: | Liu, Y.X, Sun, M, Myasnikov, A.G, Elnatan, D, Agard, D.A. | Deposit date: | 2020-06-28 | Release date: | 2021-06-30 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Full-length Hsc82 in complex with Aha1 CTD in the presence of AMPPNP To Be Published
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7Z37
| Structure of the RAF1-HSP90-CDC37 complex (RHC-II) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... | Authors: | Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G. | Deposit date: | 2022-03-01 | Release date: | 2022-09-14 | Last modified: | 2022-09-28 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation. Mol.Cell, 82, 2022
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8U1L
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6XLB
| Apo full-length Hsc82 in complex with Aha1 | Descriptor: | ATP-dependent molecular chaperone HSC82, Hsp90 co-chaperone AHA1 | Authors: | Liu, Y.X, Sun, M, Myasnikov, A.G, Elnatan, D, Agard, D.A. | Deposit date: | 2020-06-28 | Release date: | 2021-06-30 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Apo full-length Hsc82 in complex with Aha1 To Be Published
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8GFT
| Hsp90 provides platform for CRaf dephosphorylation by PP5 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... | Authors: | Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. | Deposit date: | 2023-03-08 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
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8U1N
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8FX4
| GC-C-Hsp90-Cdc37 regulatory complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Guanylyl cyclase C, Heat shock protein HSP 90-beta, ... | Authors: | Caveney, N.A, Garcia, K.C. | Deposit date: | 2023-01-23 | Release date: | 2023-07-12 | Last modified: | 2023-08-23 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insight into guanylyl cyclase receptor hijacking of the kinase-Hsp90 regulatory mechanism. Elife, 12, 2023
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8EOA
| Cryo-EM structure of human HSP90B-AIPL1 complex | Descriptor: | Aryl-hydrocarbon-interacting protein-like 1, Heat shock protein HSP 90-beta, MAGNESIUM ION, ... | Authors: | Srivastava, D, Artemyev, N.O. | Deposit date: | 2022-10-02 | Release date: | 2023-01-25 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1. Structure, 31, 2023
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7ZR5
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5FWK
| Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... | Authors: | Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. | Deposit date: | 2016-02-17 | Release date: | 2016-07-06 | Last modified: | 2019-08-21 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
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7ZR6
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5FWP
| Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... | Authors: | Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. | Deposit date: | 2016-02-18 | Release date: | 2016-10-26 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
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5FWM
| Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... | Authors: | Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. | Deposit date: | 2016-02-18 | Release date: | 2016-07-06 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
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5FWL
| Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ... | Authors: | Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A. | Deposit date: | 2016-02-18 | Release date: | 2016-07-06 | Last modified: | 2019-10-23 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352, 2016
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