5FWM

Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex

Summary for 5FWM

Entry DOI	10.2210/pdb5fwm/pdb
Related	5FWK 5FWL 5FWP
EMDB information	3342
Descriptor	HEAT SHOCK PROTEIN HSP 90 BETA, HSP90 CO-CHAPERONE CDC37, CYCLIN-DEPENDENT KINASE 4, ... (5 entities in total)
Functional Keywords	hsp90, cdc37, cdk4, chaperone, kinase, unfolding
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	4
Total formula weight	247497.04
Authors	Verba, K.A.,Wang, R.Y.R.,Arakawa, A.,Liu, Y.,Yokoyama, S.,Agard, D.A. (deposition date: 2016-02-18, release date: 2016-07-06, Last modification date: 2019-10-23)
Primary citation	Verba, K.A.,Wang, R.Y.,Arakawa, A.,Liu, Y.,Shirouzu, M.,Yokoyama, S.,Agard, D.A. Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase. Science, 352:1542-, 2016 Cited by PubMed: 27339980 DOI: 10.1126/SCIENCE.AAF5023 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (8 Å)

Structure validation