3HAL
 
 | | Crystal structure of Rabbit acidic fibroblast growth factor | | Descriptor: | CHLORIDE ION, Fibroblast growth factor 1 isoform 1, SULFATE ION | | Authors: | Blaber, M, Lee, J. | | Deposit date: | 2009-05-01 | | Release date: | 2009-12-22 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-ray structure and biophysical properties of rabbit fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
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3HOM
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3CRG
 | | Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala, Glu82Asn and Lys101Ala | | Descriptor: | FORMIC ACID, GLYCEROL, Heparin-binding growth factor 1, ... | | Authors: | Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2008-04-07 | | Release date: | 2009-02-17 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
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3CQA
 | | Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala and Lys101Ala | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | Authors: | Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2008-04-02 | | Release date: | 2009-04-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
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3CRI
 | | Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser, Glu82Asn and Lys101Ala | | Descriptor: | FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION | | Authors: | Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2008-04-07 | | Release date: | 2009-02-17 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
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3CRH
 | | Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser and Lys101Ala | | Descriptor: | Heparin-binding growth factor 1, SULFATE ION | | Authors: | Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M. | | Deposit date: | 2008-04-07 | | Release date: | 2009-02-17 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
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1FGA
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1FMM
 | | SOLUTION STRUCTURE OF NFGF-1 | | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR | | Authors: | Arunkumar, A.I, Srisailam, S, Kumar, T.K.S, Chiu, I.M, Yu, C. | | Deposit date: | 2000-08-18 | | Release date: | 2001-08-18 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure and stability of an acidic fibroblast growth factor from Notophthalmus viridescens.
J.Biol.Chem., 277, 2002
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1G82
 | | STRUCTURE OF FIBROBLAST GROWTH FACTOR 9 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FIBROBLAST GROWTH FACTOR 9, ... | | Authors: | Hecht, H.J, Adar, R, Hofmann, B, Bogin, O, Weich, H, Yayon, A. | | Deposit date: | 2000-11-16 | | Release date: | 2001-03-07 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of fibroblast growth factor 9 shows a symmetric dimer with unique receptor- and heparin-binding interfaces.
Acta Crystallogr.,Sect.D, 57, 2001
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1HKN
 | | A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate | | Descriptor: | 5-AMINO-NAPHTALENE-2-MONOSULFONATE, HEPARIN-BINDING GROWTH FACTOR 1 | | Authors: | Fernandez-Tornero, C, Lozano, R.M, Gimenez-Gallego, G, Romero, A. | | Deposit date: | 2003-03-10 | | Release date: | 2004-03-11 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
J.Biol.Chem., 278, 2003
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1IJT
 | | Crystal Structure of Fibroblast Growth Factor 4 (FGF4) | | Descriptor: | SULFATE ION, fibroblast growth factor 4 | | Authors: | Bellosta, P, Plotnikov, A.N, Eliseenkova, A.V, Basilico, C, Mohammadi, M. | | Deposit date: | 2001-04-29 | | Release date: | 2001-08-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis.
Mol.Cell.Biol., 21, 2001
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1IHK
 | | CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 9 (FGF9) | | Descriptor: | GLIA-ACTIVATING FACTOR, PHOSPHATE ION | | Authors: | Plotnikov, A.N, Eliseenkova, A.V, Ibrahimi, O.A, Lemmon, M.A, Mohammadi, M. | | Deposit date: | 2001-04-19 | | Release date: | 2001-05-02 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of fibroblast growth factor 9 reveals regions implicated in dimerization and autoinhibition.
J.Biol.Chem., 276, 2001
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1JT5
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L) | | Descriptor: | SULFATE ION, acidic fibroblast growth factor | | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | Deposit date: | 2001-08-20 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
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1JT4
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND VAL 109 REPLACED BY LEU (V109L) | | Descriptor: | FORMIC ACID, acidic fibroblast growth factor | | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | Deposit date: | 2001-08-20 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
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1JT7
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L) | | Descriptor: | FORMIC ACID, SULFATE ION, acidic fibroblast growth factor | | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | Deposit date: | 2001-08-20 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
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1JY0
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1JTC
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F) | | Descriptor: | FORMIC ACID, acidic fibroblast growth factor | | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | Deposit date: | 2001-08-20 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
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1JQZ
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag. | | Descriptor: | FORMIC ACID, acidic fibroblast growth factor | | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | Deposit date: | 2001-08-09 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
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1JT3
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V) | | Descriptor: | SULFATE ION, acidic fibroblast growth factor | | Authors: | Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. | | Deposit date: | 2001-08-20 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core
region of a beta-trefoil.
Protein Sci., 10, 2001
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1K5U
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1K5V
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4DCK
 | | Crystal structure of the C-terminus of voltage-gated sodium channel in complex with FGF13 and CaM | | Descriptor: | Calmodulin, Fibroblast growth factor 13, MAGNESIUM ION, ... | | Authors: | Chung, B.C, Wang, C, Yan, H, Pitt, G.S, Lee, S.Y. | | Deposit date: | 2012-01-17 | | Release date: | 2012-06-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of the Ternary Complex of a NaV C-Terminal Domain, a Fibroblast Growth Factor Homologous Factor, and Calmodulin.
Structure, 20, 2012
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5W59
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5W21
 | | Crystal Structure of a 1:1:1 FGF23-FGFR1c-aKlotho Ternary Complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibroblast growth factor 23, Fibroblast growth factor receptor 1, ... | | Authors: | Mohammadi, M. | | Deposit date: | 2017-06-05 | | Release date: | 2018-01-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | alpha-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.
Nature, 553, 2018
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4J23
 | | Low resolution crystal structure of the FGFR2D2D3/FGF1/SR128545 complex | | Descriptor: | Fibroblast growth factor 1, Fibroblast growth factor receptor 2 | | Authors: | Kudlinzki, D, Saxena, K, Sreeramulu, S, Schieborr, U, Dreyer, M, Schreuder, H, Schwalbe, H. | | Deposit date: | 2013-02-04 | | Release date: | 2014-02-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.882 Å) | | Cite: | Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling.
Cancer Cell, 23, 2013
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