1JT7
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L)
Summary for 1JT7
Entry DOI | 10.2210/pdb1jt7/pdb |
Related | 1JQZ |
Descriptor | acidic fibroblast growth factor, SULFATE ION, FORMIC ACID, ... (4 entities in total) |
Functional Keywords | beta-trefoil, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P05230 |
Total number of polymer chains | 4 |
Total formula weight | 67359.36 |
Authors | Brych, S.R.,Blaber, S.I.,Logan, T.M.,Blaber, M. (deposition date: 2001-08-20, release date: 2001-12-19, Last modification date: 2023-08-16) |
Primary citation | Brych, S.R.,Blaber, S.I.,Logan, T.M.,Blaber, M. Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10:2587-2599, 2001 Cited by PubMed: 11714927DOI: 10.1110/ps.ps.34701 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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