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3K58
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BU of 3k58 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dTTP ternary complex
Descriptor: DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*AP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA polymerase II, ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3K5L
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BU of 3k5l by Molmil
Crystal structure of E.coli Pol II-abasic DNA-dATP Lt(0, 3) ternary complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*TP*(3DR)P*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3K57
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BU of 3k57 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3KD5
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BU of 3kd5 by Molmil
Closed ternary complex of an RB69 gp43 fingers domain mutant complexed with an acyclic GMP terminated primer template pair and phosphonoformic acid.
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(4DG))-3'), DNA polymerase, ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2009-10-22
Release date:2011-04-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase.
J.Biol.Chem., 286, 2011
3KD1
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BU of 3kd1 by Molmil
Closed binary complex of an RB69 gp43 fingers domain mutant complexed with an acyclic GMP terminated primer template pair.
Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(4DG))-3'), DNA polymerase, ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2009-10-22
Release date:2011-04-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase.
J.Biol.Chem., 286, 2011
3L8B
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BU of 3l8b by Molmil
Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin
Descriptor: DNA (5'-D(*AP*C*TP*(G35)P*TP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*A)-3'), DNA polymerase, ...
Authors:Aller, P, Ye, Y, Wallace, S.S, Burrows, C.J, Doublie, S.
Deposit date:2009-12-30
Release date:2010-03-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin.
Biochemistry, 49, 2010
3LDS
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BU of 3lds by Molmil
Crystal structure of RB69 gp43 with DNA and dATP opposite 8-oxoG
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*(8OG)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(DDG))-3'), ...
Authors:Hogg, M, Midkiff, J, Rudnicki, J, Reha-Krantz, L, Doublie, S, Wallace, S.S.
Deposit date:2010-01-13
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69.
Biochemistry, 49, 2010
3NCI
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BU of 3nci by Molmil
RB69 DNA Polymerase Ternary Complex with dCTP Opposite dG at 1.8 angstrom resolution
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Blaha, G, Steitz, T.A, Konigsberg, W.H, Wang, J.
Deposit date:2010-06-04
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Insights into base selectivity from the 1.8 A resolution structure of an RB69 DNA polymerase ternary complex.
Biochemistry, 50, 2011
3NHG
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BU of 3nhg by Molmil
RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dTTP Opposite dG
Descriptor: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2010-06-14
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NAE
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BU of 3nae by Molmil
RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H.
Deposit date:2010-06-01
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin .
Biochemistry, 49, 2010
8G9O
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BU of 8g9o by Molmil
Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8G99
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BU of 8g99 by Molmil
Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8G9F
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BU of 8g9f by Molmil
Complete auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Mullins, E.A, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8G9L
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BU of 8g9l by Molmil
DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8G9N
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BU of 8g9n by Molmil
Partial DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 2024
8FOJ
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BU of 8foj by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the post RNA handoff state
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOH
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BU of 8foh by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the RNA synthesis state
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOC
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BU of 8foc by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOD
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BU of 8fod by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in Apo state conformation II
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOE
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BU of 8foe by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex bound to a template DNA
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
8FOK
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BU of 8fok by Molmil
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the DNA elongation state
Descriptor: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ...
Authors:Yuan, Z, Georgescu, R, Li, H, O'Donnell, M.
Deposit date:2022-12-30
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase.
Nat Commun, 14, 2023
3NE6
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BU of 3ne6 by Molmil
RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dCTP Opposite dG
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2010-06-08
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3NGI
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BU of 3ngi by Molmil
RB69 DNA Polymerase (Y567A) Ternary Complex with dTTP Opposite dG
Descriptor: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ...
Authors:Wang, M, Wang, J, Konigsberg, W.H.
Deposit date:2010-06-11
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.886 Å)
Cite:Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures.
J.Mol.Biol., 406, 2011
3LZI
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BU of 3lzi by Molmil
RB69 DNA Polymerase (Y567A) ternary complex with dATP Opposite 7,8-dihydro-8-oxoguanine
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ...
Authors:Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H.
Deposit date:2010-03-01
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
Biochemistry, 49, 2010
3MAQ
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BU of 3maq by Molmil
Crystal structure of E.coli Pol II-normal DNA-dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*CP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2010-03-24
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009

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數據於2024-05-01公開中

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