2BZ4
| structure of E.coli KAS I H298Q mutant | Descriptor: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION, SULFATE ION | Authors: | Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A. | Deposit date: | 2005-08-10 | Release date: | 2006-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J., 273, 2006
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2BZ3
| Structure of E.coli KAS I H298E mutant in complex with C12 fatty acid | Descriptor: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION, LAURIC ACID, ... | Authors: | Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A. | Deposit date: | 2005-08-10 | Release date: | 2006-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases. FEBS J., 273, 2006
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2BYZ
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2CF2
| Architecture of mammalian fatty acid synthase | Descriptor: | FATTY ACID SYNTHASE, DH DOMAIN, ER DOMAIN, ... | Authors: | Maier, T, Jenni, S, Ban, N. | Deposit date: | 2006-02-14 | Release date: | 2006-03-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Architecture of Mammalian Fatty Acid Synthase at 4.5 A Resolution. Science, 311, 2006
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2C9H
| Structure of mitochondrial beta-ketoacyl synthase | Descriptor: | MITOCHONDRIAL BETA-KETOACYL SYNTHASE, NICKEL (II) ION | Authors: | Bunkoczi, G, Wu, X, Smee, C, Gileadi, O, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, von Delft, F, Oppermann, U. | Deposit date: | 2005-12-12 | Release date: | 2005-12-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Mitochondrial Beta-Ketoacyl Synthase To be Published
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2GFX
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2GFW
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2GFY
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2GFV
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2GP6
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2GQD
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7ZMD
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7ZM9
| Ketosynthase domain 3 of Brevibacillus Brevis orphan BGC11 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative polyketide synthase | Authors: | Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. | Deposit date: | 2022-04-19 | Release date: | 2022-09-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
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7ZMA
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7ZMC
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7ZSK
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8BY8
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8CV1
| ACP1-KS-AT domains of mycobacterial Pks13 | Descriptor: | Polyketide synthase PKS13, UNKNOWN LIGAND | Authors: | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | Deposit date: | 2022-05-17 | Release date: | 2023-02-15 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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8CV0
| KS-AT domains of mycobacterial Pks13 with outward AT conformation | Descriptor: | Polyketide synthase PKS13, UNKNOWN LIGAND | Authors: | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | Deposit date: | 2022-05-17 | Release date: | 2023-02-15 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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8CUY
| ACP1-KS-AT domains of mycobacterial Pks13 | Descriptor: | 4'-PHOSPHOPANTETHEINE, Polyketide synthase PKS13, UNKNOWN LIGAND | Authors: | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | Deposit date: | 2022-05-17 | Release date: | 2023-02-15 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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8CUZ
| KS-AT domains of mycobacterial Pks13 with inward AT conformation | Descriptor: | Polyketide synthase PKS13, UNKNOWN LIGAND | Authors: | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | Deposit date: | 2022-05-17 | Release date: | 2023-02-15 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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8CJH
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8CN8
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8COV
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8CN2
| Pa.FabF-C164Q in complex with N-isobutyl-1H-pyrazole-3-carboxamide | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ~{N}-(2-methylpropyl)-1~{H}-pyrazole-3-carboxamide | Authors: | Georgiou, C, Brenk, R. | Deposit date: | 2023-02-21 | Release date: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023
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