8CV0

KS-AT domains of mycobacterial Pks13 with outward AT conformation

Summary for 8CV0

• Entry DOI: 10.2210/pdb8cv0/pdb
• Related: 7UK4 8CUY 8CUZ 8CV1
• EMDB information: 26574 27002 27003 27004 27005
• Descriptor: Polyketide synthase PKS13, UNKNOWN LIGAND (2 entities in total)
• Functional Keywords: mycolic acid synthesis, ketosynthase, acyltransferase, multi-domain assembly, biosynthetic protein
• Biological source: Mycolicibacterium smegmatis MC2 155
• Total number of polymer chains: 2
• Total formula weight: 389961.47

Authors

Kim, S.K.,Dickinson, M.S.,Finer-Moore, J.S.,Rosenberg, O.S.,Stroud, R.M. (deposition date: 2022-05-17, release date: 2023-02-15, Last modification date: 2023-03-29)

• Primary citation: Kim, S.K.,Dickinson, M.S.,Finer-Moore, J.,Guan, Z.,Kaake, R.M.,Echeverria, I.,Chen, J.,Pulido, E.H.,Sali, A.,Krogan, N.J.,Rosenberg, O.S.,Stroud, R.M.; Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.; Nat.Struct.Mol.Biol., 30:296-308, 2023; PubMed: 36782050; DOI: 10.1038/s41594-022-00918-0

Experimental method

ELECTRON MICROSCOPY (3.1 Å)