PDB: 361 resultsInfo pagesStatus searchChemie searchBIRD

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7ONU	Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-Tyr Descriptor: 3-hydroxyacyl-CoA dehydrogenase type-2, MAGNESIUM ION, Mitochondrial Precursor tRNA-Tyr, ... Authors: Bhatta, A, Dienemann, C, Cramer, P, Hillen, H.S. Deposit date: 2021-05-26 Release date: 2021-08-11 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of RNA processing by human mitochondrial RNase P. Nat.Struct.Mol.Biol., 28, 2021
7E3X	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from exiguobacterium Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase Authors: Chen, L, Tang, J, Yuan, S, Zhang, F, Chen, S. Deposit date: 2021-02-09 Release date: 2021-09-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7E28	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium Descriptor: Oxidoreductase Authors: Chen, L, Tang, J, Yuan, S. Deposit date: 2021-02-05 Release date: 2021-09-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7E24	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase Authors: Chen, L, Tang, J, Yuan, S. Deposit date: 2021-02-04 Release date: 2021-09-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7203 Å) Cite: Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7BTM	SDR protein/resistance protein NapW Descriptor: Short chain dehydrogenase Authors: Wen, W.H, Tang, G.L. Deposit date: 2020-04-02 Release date: 2021-10-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.08311653 Å) Cite: Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics. Nat Commun, 12, 2021
7BSX	SDR protein NapW-NADP Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase Authors: Wen, W.H, Tang, G.L. Deposit date: 2020-03-31 Release date: 2021-10-06 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics. Nat Commun, 12, 2021
7E6O	Crystal structure of polyol dehydrogenase from Paracoccus denitrificans Descriptor: Short-chain dehydrogenase/reductase SDR Authors: Sha, F, Zheng, Y.C. Deposit date: 2021-02-22 Release date: 2022-03-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of polyol dehydrogenase from Paracoccus denitrificans To Be Published
7ULH	Crystal Structure of a Short chain dehydrogenase from Mycobacterium avium 104 Descriptor: Short chain dehydrogenase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-04-04 Release date: 2022-04-13 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of Crystal Structure of a Short chain dehydrogenase from Mycobacterium avium 104 to be published
8DT1	Crystal Structure of a Putative D-beta-hydroxybutyrate dehydrogenase from Burkholderia cenocepacia J2315 in complex with NAD Descriptor: 3-hydroxybutyrate dehydrogenase, CITRIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2022-07-25 Release date: 2022-08-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal Structure of a Putative D-beta-hydroxybutyrate dehydrogenase from Burkholderia cenocepacia J2315 in complex with NAD To Be Published
8B5T	Crystal structure of Quinonoid dihydropteridine reductase from Leishmania major Descriptor: Quinonoid dihydropteridine reductase Authors: Robinson, D.A, Fairlamb, A.H. Deposit date: 2022-09-24 Release date: 2022-10-05 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of Quinonoid dihydropteridine reductase from Leishmania major To Be Published
8B5U	Crystal structure of Quinonoid dihydropteridine reductase from Leishmania donovani Descriptor: Quinonoid dihydropteridine reductase Authors: Robinson, D.A, Fairlamb, A.H. Deposit date: 2022-09-24 Release date: 2022-10-19 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of Quinonoid dihydropteridine reductase from Leishmania donovani To Be Published
7X3Z	Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NAD Descriptor: (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one, 17-beta-hydroxysteroid dehydrogenase type 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Li, T, Lin, S.X, Yin, H. Deposit date: 2022-03-01 Release date: 2023-01-25 Method: X-RAY DIFFRACTION (2.25 Å) Cite: New insights into the substrate inhibition of human 17 beta-hydroxysteroid dehydrogenase type 1. J.Steroid Biochem.Mol.Biol., 228, 2023
8CVN	Cryo-EM Structure of Human 15-PGDH in Complex with Small Molecule SW209415 Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 2-[butyl(oxidanyl)-$l^{3}-sulfanyl]-4-(2,3-dimethylimidazol-4-yl)-6-(1,3-thiazol-2-yl)thieno[2,3-b]pyridin-3-amine Authors: Huang, W, Taylor, D.J. Deposit date: 2022-05-18 Release date: 2023-03-01 Last modified: 2023-03-29 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system. Nat Commun, 14, 2023
8FD8	human 15-PGDH with NADH bound Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Authors: Huang, W, Taylor, D. Deposit date: 2022-12-02 Release date: 2023-03-08 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system. Nat Commun, 14, 2023
7X5J	ACP-dependent oxoacyl reductase Descriptor: 3-oxoacyl-ACP reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHENYLALANINE Authors: Wang, S, Bai, L. Deposit date: 2022-03-04 Release date: 2023-03-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: ACP-dependent oxoacyl reductase To Be Published
8CWL	Cryo-EM structure of Human 15-PGDH in complex with small molecule SW222746 Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 2-methyl-6-[7-(piperidine-1-carbonyl)quinoxalin-2-yl]isoquinolin-1(2H)-one Authors: Huang, W, Taylor, D.J. Deposit date: 2022-05-19 Release date: 2023-03-08 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system. Nat Commun, 14, 2023
8A7S	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal NADP bound Descriptor: MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Kabasakal, B.V, Murray, J.W. Deposit date: 2022-06-21 Release date: 2023-04-05 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.542 Å) Cite: Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8AEW	Malonyl-CoA reductase from Chloroflexus aurantiacus - N-terminal Apo Descriptor: Short-chain dehydrogenase/reductase SDR Authors: Kabasakal, B.V, Murray, J.W. Deposit date: 2022-07-13 Release date: 2023-04-05 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.72 Å) Cite: Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8A30	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal Apo Descriptor: MAGNESIUM ION, Short-chain dehydrogenase/reductase SDR Authors: Kabasakal, B.V, Murray, J.W. Deposit date: 2022-06-06 Release date: 2023-04-05 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8AEO	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal R773A variant Descriptor: SULFATE ION, Short-chain dehydrogenase/reductase SDR Authors: Kabasakal, B.V, Murray, J.W. Deposit date: 2022-07-13 Release date: 2023-04-05 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8AEQ	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal R773Q variant Descriptor: Short-chain dehydrogenase/reductase SDR Authors: Kabasakal, B.V, Murray, J.W. Deposit date: 2022-07-13 Release date: 2023-04-05 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8AER	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal Y731A variant Descriptor: MAGNESIUM ION, Short-chain dehydrogenase/reductase SDR Authors: Kabasakal, B.V, Murray, J.W. Deposit date: 2022-07-13 Release date: 2023-04-05 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8A8T	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal NADP and malonate bound Descriptor: MALONATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Kabasakal, B.V, Murray, J.W. Deposit date: 2022-06-24 Release date: 2023-04-05 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8AET	Malonyl-CoA reductase from Chloroflexus aurantiacus - C-terminal E779W variant Descriptor: SULFATE ION, Short-chain dehydrogenase/reductase SDR Authors: Kabasakal, B.V, Murray, J.W. Deposit date: 2022-07-13 Release date: 2023-04-05 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction. Biochimie, 219, 2023
8HI4	Cryo-EM structure of the bi-functional malonyl-CoA reductase from Roseiflexus castenholzii Descriptor: Short-chain dehydrogenase/reductase SDR Authors: Zhang, X, Xu, X, Xin, J. Deposit date: 2022-11-18 Release date: 2023-05-31 Last modified: 2023-09-20 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: Structural basis of a bi-functional malonyl-CoA reductase (MCR) from the photosynthetic green non-sulfur bacterium Roseiflexus castenholzii. Mbio, 14, 2023

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