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5D96
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BU of 5d96 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1
Descriptor: Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1, Light chain of Fab fragment from an antibody targeting mouse and human QSOX1, Sulfhydryl oxidase 1
Authors:Fass, D, Grossman, I.
Deposit date:2015-08-18
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
5D93
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BU of 5d93 by Molmil
Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody
Descriptor: Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody, Sulfhydryl oxidase 1
Authors:Grossman, I, Fass, D.
Deposit date:2015-08-18
Release date:2016-02-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
7P9D
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BU of 7p9d by Molmil
Crystal structure of Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase
Authors:Singh, R.K, Marchetti, G.M, Hippler, M, Kuemmel, D.
Deposit date:2021-07-27
Release date:2022-01-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.
J.Struct.Biol., 214, 2021
7P9E
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BU of 7p9e by Molmil
Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain CS mutant
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase
Authors:Fuesser, F, Kuemmel, D.
Deposit date:2021-07-27
Release date:2022-01-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.
J.Struct.Biol., 214, 2021
4LL1
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BU of 4ll1 by Molmil
The structure of the TRX and TXNIP complex
Descriptor: Thioredoxin, Thioredoxin-interacting protein
Authors:Hwang, J, Kim, M.H.
Deposit date:2013-07-09
Release date:2014-02-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
4LL4
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BU of 4ll4 by Molmil
The structure of the TRX and TXNIP complex
Descriptor: Thioredoxin, Thioredoxin-interacting protein
Authors:Hwang, J, Kim, M.H.
Deposit date:2013-07-09
Release date:2014-02-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
7QNG
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BU of 7qng by Molmil
Structure of a MHC I-Tapasin-ERp57 complex
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
Authors:Mueller, I.K, Thomas, C, Trowitzsch, S, Tampe, R.
Deposit date:2021-12-20
Release date:2022-09-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity.
Nat Commun, 13, 2022
7QPD
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BU of 7qpd by Molmil
Structure of the human MHC I peptide-loading complex editing module
Descriptor: Beta-2-microglobulin, Calreticulin, HLA class I histocompatibility antigen, ...
Authors:Domnick, A, Susac, L, Trowitzsch, S, Thomas, C, Tampe, R.
Deposit date:2022-01-03
Release date:2022-07-20
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Molecular basis of MHC I quality control in the peptide loading complex.
Nat Commun, 13, 2022
5E4W
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BU of 5e4w by Molmil
Crystal structure of cpSRP43 chromodomains 2 and 3 in complex with the Alb3 tail
Descriptor: CALCIUM ION, GLYCEROL, Inner membrane protein ALBINO3, ...
Authors:Horn, A, Ahmed, Y.L, Wild, K, Sinning, I.
Deposit date:2015-10-07
Release date:2015-12-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction.
Nat Commun, 6, 2015
5GU7
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BU of 5gu7 by Molmil
Crystal Structure of human ERp44 form II
Descriptor: Endoplasmic reticulum resident protein 44
Authors:Watanabe, S, Inaba, K.
Deposit date:2016-08-26
Release date:2017-04-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5GU6
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BU of 5gu6 by Molmil
Crystal structure of Human ERp44 form I
Descriptor: CHLORIDE ION, Endoplasmic reticulum resident protein 44
Authors:Watanabe, S, Inaba, K.
Deposit date:2016-08-26
Release date:2017-04-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3P2A
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BU of 3p2a by Molmil
Crystal Structure of Thioredoxin 2 from Yersinia pestis
Descriptor: FORMIC ACID, Putative thioredoxin-like protein, ZINC ION
Authors:Kim, Y, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-10-01
Release date:2010-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Crystal Structure of Thioredoxin 2 from Yersinia pestis
TO BE PUBLISHED
5XF7
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BU of 5xf7 by Molmil
Crystal structure of human protein disulfide isomerase-like protein of the testis
Descriptor: Protein disulfide-isomerase-like protein of the testis
Authors:Li, H, Li, J, Liu, Y, Liang, H.
Deposit date:2017-04-08
Release date:2017-12-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.381 Å)
Cite:Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity
J. Biol. Chem., 293, 2018
5XOC
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BU of 5xoc by Molmil
Crystal structure of human Smad3-FoxH1 complex
Descriptor: Mothers against decapentaplegic homolog 3, Thioredoxin 1,Forkhead box protein H1
Authors:Miyazono, K, Ito, T, Tanokura, M.
Deposit date:2017-05-27
Release date:2018-03-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Hydrophobic patches on SMAD2 and SMAD3 determine selective binding to cofactors
Sci Signal, 11, 2018
5XWM
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BU of 5xwm by Molmil
human ERp44 zinc-bound form
Descriptor: CHLORIDE ION, Endoplasmic reticulum resident protein 44, ZINC ION
Authors:Watanabe, S, Harayama, M, Inaba, K.
Deposit date:2017-06-30
Release date:2019-01-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Zinc regulates ERp44-dependent protein quality control in the early secretory pathway.
Nat Commun, 10, 2019
6ZYW
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BU of 6zyw by Molmil
Outer Dynein Arm-Shulin complex - overall structure (Tetrahymena thermophila)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
Authors:Mali, G.R, Abid Ali, F, Lau, C.K, Carter, A.P.
Deposit date:2020-08-03
Release date:2021-01-20
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (8.78 Å)
Cite:Shulin packages axonemal outer dynein arms for ciliary targeting.
Science, 371, 2021
7BVV
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BU of 7bvv by Molmil
Crystal structure of sulfonic peroxiredoxin Ahp1 in complex with thioredoxin Trx2
Descriptor: Peroxiredoxin AHP1, Thioredoxin-2
Authors:Lian, F.M, Jiang, Y.L, Yang, W, Yang, X.
Deposit date:2020-04-11
Release date:2020-07-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of sulfonic peroxiredoxin Ahp1 in complex with thioredoxin Trx2 mimics a conformational intermediate during the catalytic cycle.
Int.J.Biol.Macromol., 161, 2020
4DSS
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BU of 4dss by Molmil
Crystal structure of peroxiredoxin Ahp1 from Saccharomyces cerevisiae in complex with thioredoxin Trx2
Descriptor: Peroxiredoxin type-2, Thioredoxin-2
Authors:Lian, F.M, Yu, J, Ma, X.X, Yu, X.J, Chen, Y, Zhou, C.Z.
Deposit date:2012-02-19
Release date:2012-04-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Snapshots of Yeast Alkyl Hydroperoxide Reductase Ahp1 Peroxiredoxin Reveal a Novel Two-cysteine Mechanism of Electron Transfer to Eliminate Reactive Oxygen Species.
J.Biol.Chem., 287, 2012
1OAZ
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BU of 1oaz by Molmil
IgE Fv SPE7 complexed with a recombinant thioredoxin
Descriptor: IMMUNOGLOBULIN E, THIOREDOXIN 1
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-01-21
Release date:2004-01-15
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
6N7W
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BU of 6n7w by Molmil
Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes)
Descriptor: DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
4IJ3
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BU of 4ij3 by Molmil
Oxidoreductase Fragment of Human QSOX1 in Complex with a FAB Fragment from an Anti- Human QSOX1 Antibody
Descriptor: Heavy chain of FAB fragment, Light chain of FAB fragment, PHOSPHATE ION, ...
Authors:Fass, D, Grossman, I.
Deposit date:2012-12-21
Release date:2013-11-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:An Inhibitory Antibody Blocks the First Step in the Dithiol/Disulfide Relay Mechanism of the Enzyme QSOX1.
J.Mol.Biol., 425, 2013
6ENY
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BU of 6eny by Molmil
Structure of the human PLC editing module
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ...
Authors:Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R.
Deposit date:2017-10-07
Release date:2017-11-29
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structure of the human MHC-I peptide-loading complex.
Nature, 551, 2017
5HQP
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BU of 5hqp by Molmil
Crystal structure of the ERp44-peroxiredoxin 4 complex
Descriptor: Endoplasmic reticulum resident protein 44, Peroxiredoxin-4
Authors:Yang, K, Li, D.F, Wang, X, Wang, C.C.
Deposit date:2016-01-22
Release date:2016-10-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention.
Structure, 24, 2016
5IKN
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BU of 5ikn by Molmil
Crystal Structure of the T7 Replisome in the Absence of DNA
Descriptor: DNA primase/helicase, DNA-directed DNA polymerase, Thioredoxin-1
Authors:Wallen, J.R, Ellenberger, T.
Deposit date:2016-03-03
Release date:2016-12-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.802 Å)
Cite:Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome.
Structure, 25, 2017
3APQ
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BU of 3apq by Molmil
Crystal structure of J-Trx1 fragment of ERdj5
Descriptor: DnaJ homolog subfamily C member 10
Authors:Inaba, K, Suzuki, M, Nagata, K.
Deposit date:2010-10-20
Release date:2011-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5.
Mol.Cell, 41, 2011

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