7QNG

Structure of a MHC I-Tapasin-ERp57 complex

Summary for 7QNG

Entry DOI	10.2210/pdb7qng/pdb
Descriptor	Tapasin, Protein disulfide-isomerase A3, H-2 class I histocompatibility antigen, D-B alpha chain, ... (6 entities in total)
Functional Keywords	mhc i, chaperone complex, endoplasmic reticulum, peptide editing, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	146396.96
Authors	Mueller, I.K.,Thomas, C.,Trowitzsch, S.,Tampe, R. (deposition date: 2021-12-20, release date: 2022-09-28, Last modification date: 2024-01-31)
Primary citation	Muller, I.K.,Winter, C.,Thomas, C.,Spaapen, R.M.,Trowitzsch, S.,Tampe, R. Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity. Nat Commun, 13:5383-5383, 2022 Cited by PubMed: 36104323 DOI: 10.1038/s41467-022-32841-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation