3QQD
| Human SOD1 H80R variant, P212121 crystal form | Descriptor: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Schirf, V, Demeler, B, Carroll, M.C, Culotta, V.C, Hart, P.J. | Deposit date: | 2011-02-15 | Release date: | 2011-03-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.653 Å) | Cite: | Disrupted zinc-binding sites in structures of pathogenic SOD1 variants D124V and H80R. Biochemistry, 49, 2010
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6SPH
| A4V MUTANT OF HUMAN SUPEROXIDE DISMUTASE 1 WITH EBSELEN BOND IN C2 SPACE GROUP | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, N-phenyl-2-selanylbenzamide, ... | Authors: | Shahid, M, Chantadul, V, Amporndanai, K, Wright, G, Antonyuk, S, Hasnain, S. | Deposit date: | 2019-09-01 | Release date: | 2020-03-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy. Commun Biol, 3, 2020
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6SPI
| A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4 | Descriptor: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | Authors: | Chantadul, V, Amporndanai, K, Wright, G, Antonyuk, S, Hasnain, S. | Deposit date: | 2019-09-01 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy. Commun Biol, 3, 2020
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3RE0
| Crystal structure of human apo Cu,Zn superoxide dismutase (SOD1) complexed with cisplatin | Descriptor: | Cisplatin, Superoxide dismutase [Cu-Zn] | Authors: | Bertini, I, Blazevits, O, Calderone, V, Jaifei, M, Vieru, M, Amori, I, Cozzolino, M, Carri, M.T, Banci, L. | Deposit date: | 2011-04-02 | Release date: | 2012-04-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Interaction of cisplatin with human superoxide dismutase. J.Am.Chem.Soc., 134, 2012
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3S0P
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3SOD
| CHANGES IN CRYSTALLOGRAPHIC STRUCTURE AND THERMOSTABILITY OF A CU,ZN SUPEROXIDE DISMUTASE MUTANT RESULTING FROM THE REMOVAL OF BURIED CYSTEINE | Descriptor: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | Authors: | Mcree, D.E, Redford, S.M, Getzoff, E.D, Lepock, J.R, Hallewell, R.A, Tainer, J.A. | Deposit date: | 1990-06-26 | Release date: | 1993-04-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Changes in crystallographic structure and thermostability of a Cu,Zn superoxide dismutase mutant resulting from the removal of a buried cysteine. J.Biol.Chem., 265, 1990
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6VBS
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3T5W
| 2ME modified human SOD1 | Descriptor: | COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | Authors: | Ihara, K, Yamaguchi, Y, Torigoe, H, Wakatsuki, S, Taniguchi, N, Suzuki, K, Fujiwara, N. | Deposit date: | 2011-07-28 | Release date: | 2012-08-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural switching of Cu,Zn-superoxide dismutases at loop VI: insights from the crystal structure of 2-mercaptoethanol-modified enzyme Biosci.Rep., 32, 2012
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2JCW
| REDUCED BRIDGE-BROKEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE | Descriptor: | COPPER (I) ION, CU/ZN SUPEROXIDE DISMUTASE, ZINC ION | Authors: | Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D. | Deposit date: | 1998-12-21 | Release date: | 1999-06-08 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A structure-based mechanism for copper-zinc superoxide dismutase. Biochemistry, 38, 1999
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2JLP
| Crystal structure of human extracellular copper-zinc superoxide dismutase. | Descriptor: | COPPER (II) ION, EXTRACELLULAR SUPEROXIDE DISMUTASE (CU-ZN), THIOCYANATE ION, ... | Authors: | Antonyuk, S.V, Strange, R.W, Marklund, S.L, Hasnain, S.S. | Deposit date: | 2008-09-14 | Release date: | 2009-03-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Structure of Human Extracellular Copper-Zinc Superoxide Dismutase at 1.7 A Resolution: Insights Into Heparin and Collagen Binding. J.Mol.Biol., 388, 2009
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2K4W
| The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica | Descriptor: | COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Mori, M, Jimenez, B, Piccioli, M, Battistoni, A, Sette, M, Structural Proteomics in Europe (SPINE) | Deposit date: | 2008-06-20 | Release date: | 2008-11-18 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica: Structural Insights To Understand the Evolution toward the Dimeric Structure. Biochemistry, 47, 2008
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2LU5
| Structure and chemical shifts of Cu(I),Zn(II) superoxide dismutase by solid-state NMR | Descriptor: | COPPER (II) ION, Superoxide dismutase [Cu-Zn] | Authors: | Knight, M.J, Pell, A.J, Bertini, I, Felli, I.C, Gonnelli, L, Pierattelli, R, Herrmann, T, Emsley, L, Pintacuda, G. | Deposit date: | 2012-06-08 | Release date: | 2012-06-27 | Last modified: | 2023-06-14 | Method: | SOLID-STATE NMR | Cite: | Structure and backbone dynamics of a microcrystalline metalloprotein by solid-state NMR. Proc.Natl.Acad.Sci.USA, 109, 2012
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7T8H
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7T8F
| G93A mutant of human SOD1 bound with Ebselen in P21 space group | Descriptor: | ACETATE ION, N-phenyl-2-selanylbenzamide, Superoxide dismutase [Cu-Zn], ... | Authors: | Amporndanai, K, Hasnain, S.S. | Deposit date: | 2021-12-16 | Release date: | 2023-01-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Disease Onset and its course are delayed by on-target Cellular SOD1 Engagement of Organo-selenium drug compounds for Amyotrophic Lateral Sclerosis To Be Published
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7T8G
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7T8E
| G93A mutant of human SOD1 in P21 space group | Descriptor: | ACETATE ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ... | Authors: | Amporndanai, K, Hasnain, S.S. | Deposit date: | 2021-12-16 | Release date: | 2023-01-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Disease Onset and its course are delayed by on-target Cellular SOD1 Engagement of Organo-selenium drug compounds for Amyotrophic Lateral Sclerosis To Be Published
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2MP3
| Truncated L126Z-sod1 in DPC micelle | Descriptor: | Superoxide dismutase [Cu-Zn] | Authors: | Lim, L, Song, J. | Deposit date: | 2014-05-10 | Release date: | 2015-05-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Mechanism for transforming cytosolic SOD1 into integral membrane proteins of organelles by ALS-causing mutations Biochim.Biophys.Acta, 1848, 2015
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2NAM
| Full-length WT SOD1 in DPC MICELLE | Descriptor: | Superoxide dismutase [Cu-Zn] | Authors: | Lim, L, Song, J. | Deposit date: | 2016-01-06 | Release date: | 2016-12-14 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | SALS-linked WT-SOD1 adopts a highly similar helical conformation as FALS-causing L126Z-SOD1 in a membrane environment Biochim.Biophys.Acta, 1858, 2016
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2NNX
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2C9U
| 1.24 Angstroms resolution structure of as-isolated Cu-Zn Human Superoxide dismutase | Descriptor: | ACETATE ION, COPPER (II) ION, SULFATE ION, ... | Authors: | Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine S, J.S, Hasnain, S. | Deposit date: | 2005-12-14 | Release date: | 2005-12-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes. J.Mol.Biol., 356, 2006
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2C9V
| Atomic resolution structure of Cu-Zn Human Superoxide dismutase | Descriptor: | COPPER (II) ION, SODIUM ION, SULFATE ION, ... | Authors: | Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine, J.S, Hasnain, S.S. | Deposit date: | 2005-12-14 | Release date: | 2005-12-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes. J.Mol.Biol., 356, 2006
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2C9S
| 1.24 Angstroms resolution structure of Zn-Zn Human Superoxide dismutase | Descriptor: | ACETATE ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ... | Authors: | Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine S, J.S, Hasnain, S. | Deposit date: | 2005-12-14 | Release date: | 2005-12-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes. J.Mol.Biol., 356, 2006
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2E47
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2E46
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2GBT
| C6A/C111A CuZn Superoxide dismutase | Descriptor: | COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Hornberg, A, Logan, D.T, Marklund, S.L, Oliveberg, M. | Deposit date: | 2006-03-11 | Release date: | 2007-01-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase J.Mol.Biol., 365, 2007
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