7T8H

G93A mutant of human SOD1 bound with MR6-26-2 in P21 space group

Summary for 7T8H

• Entry DOI: 10.2210/pdb7t8h/pdb
• Descriptor: Superoxide dismutase [Cu-Zn], ZINC ION, ACETATE ION, ... (6 entities in total)
• Functional Keywords: sod1, als, drug discovery, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 32838.44

Authors

Amporndanai, K.,Hasnain, S.S. (deposition date: 2021-12-16, release date: 2023-01-25, Last modification date: 2023-10-25)

• Primary citation: Amporndanai, K.,Watanabe, S.,Awais, R.,Latham, C.,O Neill, P.M.,Yamanaka, K.,Hasnain, S.S.; Disease Onset and its course are delayed by on-target Cellular SOD1 Engagement of Organo-selenium drug compounds for Amyotrophic Lateral Sclerosis; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)