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5MMJ
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BU of 5mmj by Molmil
Structure of the small subunit of the chloroplast ribosome
Descriptor: 16S ribosomal RNA, 30S ribosomal protein 2, chloroplastic, ...
Authors:Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N.
Deposit date:2016-12-10
Release date:2017-01-11
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The complete structure of the chloroplast 70S ribosome in complex with translation factor pY.
EMBO J., 36, 2017
5MDU
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BU of 5mdu by Molmil
Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe.
Descriptor: CHLORIDE ION, GLYCEROL, Rpb7-binding protein seb1, ...
Authors:Wittmann, S, Renner, M, El Omari, K, Adams, O, Vasiljeva, L, Grimes, J.
Deposit date:2016-11-13
Release date:2017-04-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:The conserved protein Seb1 drives transcription termination by binding RNA polymerase II and nascent RNA.
Nat Commun, 8, 2017
5M8I
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BU of 5m8i by Molmil
Solution structure of CUG-BP2 RRM3 in complex with 5'-UUUAA-3' RNA
Descriptor: CUGBP Elav-like family member 2, RNA (5'-R(*UP*UP*UP*AP*A)-3')
Authors:Diarra dit Konte, N, Damberger, F.F, Allain, F.H.T.
Deposit date:2016-10-28
Release date:2017-10-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Aromatic side-chain conformational switch on the surface of the RNA Recognition Motif enables RNA discrimination.
Nat Commun, 8, 2017
5LXY
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BU of 5lxy by Molmil
Structure of the minimal RBM7 - ZCCHC8 Complex
Descriptor: BROMIDE ION, RNA-binding protein 7, Zinc finger CCHC domain-containing protein 8
Authors:Falk, S, Finogenova, K, Benda, C, Conti, E.
Deposit date:2016-09-23
Release date:2016-12-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
5LXR
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BU of 5lxr by Molmil
Structure of the minimal RBM7 - ZCCHC8 Complex
Descriptor: BROMIDE ION, CHLORIDE ION, RNA-binding protein 7, ...
Authors:Falk, S, Finogenova, K, Benda, C, Conti, E.
Deposit date:2016-09-22
Release date:2016-12-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the RBM7-ZCCHC8 core of the NEXT complex reveals connections to splicing factors.
Nat Commun, 7, 2016
5LSO
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BU of 5lso by Molmil
Crystal structure of SPF45 UHM domain with cyclic peptide inhibitor
Descriptor: LYS-SER-ARG-TRP-ASP-GLU, Splicing factor 45
Authors:Jagtap, P.K.A, Garg, D, Sattler, M.
Deposit date:2016-09-05
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
J. Med. Chem., 59, 2016
5LSL
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BU of 5lsl by Molmil
Crystal structure of yeast Hsh49p in complex with Cus1p binding domain.
Descriptor: Cold sensitive U2 snRNA suppressor 1, Protein HSH49
Authors:van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K.
Deposit date:2016-09-02
Release date:2017-04-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.
RNA, 23, 2017
5LSB
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BU of 5lsb by Molmil
Crystal structure of yeast Hsh49p in complex with Cus1p binding domain.
Descriptor: Cold sensitive U2 snRNA suppressor 1, Protein HSH49
Authors:van Roon, A.M, Obayashi, E, Sposito, B, Oubridge, C, Nagai, K.
Deposit date:2016-08-24
Release date:2017-04-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.
RNA, 23, 2017
5LQW
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BU of 5lqw by Molmil
yeast activated spliceosome
Descriptor: Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ...
Authors:Rauhut, R, Luehrmann, R.
Deposit date:2016-08-17
Release date:2016-10-05
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
Science, 6306, 2016
5LJ5
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BU of 5lj5 by Molmil
Overall structure of the yeast spliceosome immediately after branching.
Descriptor: CWC15, CWC22, Exon 1 (5' exon) of UBC4 pre-mRNA, ...
Authors:Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K.
Deposit date:2016-07-17
Release date:2016-08-31
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
5LJ3
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BU of 5lj3 by Molmil
Structure of the core of the yeast spliceosome immediately after branching
Descriptor: CEF1, CLF1, CWC15, ...
Authors:Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K.
Deposit date:2016-07-17
Release date:2016-08-03
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the spliceosome immediately after branching.
Nature, 537, 2016
5KWQ
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BU of 5kwq by Molmil
Two Tandem RRM Domains of FBP-Interacting Repressor (FIR), also Known as PUF60
Descriptor: Poly(U)-binding-splicing factor PUF60
Authors:Crichlow, G.V, Yang, Y, Zhou, H, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-18
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5KW6
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BU of 5kw6 by Molmil
Two Tandem RRM Domains of PUF60 Bound to an AdML Pre-mRNA 3' Splice Site Analogue with a Modified Binding-Site Nucleic Acid Base
Descriptor: DNA (30-MER), Poly(U)-binding-splicing factor PUF60
Authors:Crichlow, G.V, Hsiao, H.-H, Albright, R, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-15
Release date:2017-08-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5KW1
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BU of 5kw1 by Molmil
Crystal Structure of the Two Tandem RRM Domains of PUF60 Bound to a Modified AdML Pre-mRNA 3' Splice Site Analogue
Descriptor: CHLORIDE ION, DNA/RNA (30-MER), Poly(U)-binding-splicing factor PUF60
Authors:Crichlow, G.V, Hsiao, H.-H, Albright, R, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-15
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5KVY
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BU of 5kvy by Molmil
CRYSTAL STRUCTURE OF THE TWO TANDEM RRM DOMAINS OF PUF60 BOUND TO A PORTION OF AN ADML PRE-MRNA 3' SPLICE SITE ANALOG
Descriptor: CHLORIDE ION, DNA (30-MER), Poly(U)-binding-splicing factor PUF60
Authors:Hsiao, H.-H, Crichlow, G.V, Albright, R.A, Murphy, J.W, Lolis, E.J, Braddock, D.T.
Deposit date:2016-07-15
Release date:2017-08-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Plos One, 15, 2020
5K1H
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BU of 5k1h by Molmil
eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex. from the structure of a partial yeast 48S preinitiation complex in closed conformation.
Descriptor: Eukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail
Authors:Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y.
Deposit date:2016-05-18
Release date:2016-07-13
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 63, 2016
5K0Y
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BU of 5k0y by Molmil
m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ...
Authors:Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y.
Deposit date:2016-05-17
Release date:2016-07-13
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 63, 2016
5ITH
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BU of 5ith by Molmil
TIA-1 RRM2 recognition of target oligonucleotide
Descriptor: DNA (5'-D(*AP*CP*TP*CP*C*TP*TP*TP*TP*T)-3'), Nucleolysin TIA-1 isoform p40
Authors:Waris, S, Wilce, J.A, Wilce, M.C.
Deposit date:2016-03-16
Release date:2017-02-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:TIA-1 RRM23 binding and recognition of target oligonucleotides.
Nucleic Acids Res., 45, 2017
5IQQ
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BU of 5iqq by Molmil
Crystal structure of the human RBM7 RRM domain
Descriptor: RNA-binding protein 7
Authors:Sofos, N, Winkler, M.B.L, Brodersen, D.E.
Deposit date:2016-03-11
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:RRM domain of human RBM7: purification, crystallization and structure determination.
Acta Crystallogr.,Sect.F, 72, 2016
5IM0
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BU of 5im0 by Molmil
Crystal structure of the RNA recognition motif of mRNA decay regulator AUF1
Descriptor: Heterogeneous nuclear ribonucleoprotein D0
Authors:Choi, Y.J, Chang, J.H.
Deposit date:2016-03-05
Release date:2016-08-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the N-Terminal RNA Recognition Motif of mRNA Decay Regulator AUF1.
Biomed Res Int, 2016, 2016
5IFN
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BU of 5ifn by Molmil
Human PSPC1 Homodimer
Descriptor: Paraspeckle component 1
Authors:Knott, G.J, Passon, D.M, Bond, C.S.
Deposit date:2016-02-26
Release date:2017-08-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Human PSPC1 Homodimer
To Be Published
5IFM
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BU of 5ifm by Molmil
Human NONO (p54nrb) Homodimer
Descriptor: CHLORIDE ION, GLYCEROL, Non-POU domain-containing octamer-binding protein, ...
Authors:Knott, G.J, Bond, C.S.
Deposit date:2016-02-26
Release date:2016-11-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry.
Acta Crystallogr D Struct Biol, 72, 2016
5HO4
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BU of 5ho4 by Molmil
Crystal structure of hnRNPA2B1 in complex with 10-mer RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3')
Authors:Wu, B.X, Su, S.C, Gan, J.H, Ma, J.B.
Deposit date:2016-01-19
Release date:2017-02-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
5GVQ
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BU of 5gvq by Molmil
Solution structure of the first RRM domain of human spliceosomal protein SF3b49
Descriptor: Splicing factor 3B subunit 4
Authors:Kuwasako, K, Nameki, N, Tsuda, K, Takahashi, M, Sato, A, Tochio, N, Inoue, M, Terada, T, Kigawa, T, Kobayashi, N, Shirouzu, M, Ito, T, Sakamoto, T, Wakamatsu, K, Guntert, P, Takahashi, S, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2016-09-06
Release date:2017-04-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment.
Protein Sci., 26, 2017
5GMK
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BU of 5gmk by Molmil
Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution
Descriptor: 5'-Exon, 5'-Splicing Site, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Wan, R, Yan, C, Bai, R, Huang, G, Shi, Y.
Deposit date:2016-07-14
Release date:2016-08-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of a yeast catalytic step I spliceosome at 3.4 angstrom resolution
Science, 353, 2016

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