PDB: 858 resultsInfo pagesStatus searchChemie searchBIRD

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9F1S	Structure of UP1 S4ES6E phosphomimetic mutant Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-20 Release date: 2024-05-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure of UP1 S4ES6E phosphomimetic mutant To Be Published
8Y7E	Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part Descriptor: PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ... Authors: Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. Deposit date: 2024-02-04 Release date: 2024-03-13 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.66 Å) Cite: Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome. Science, 383, 2024
8Y6O	Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. Deposit date: 2024-02-02 Release date: 2024-03-20 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome. Science, 383, 2024
8XXN	Cryo-EM structure of the human 43S ribosome with PDCD4 Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. Deposit date: 2024-01-18 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 2024
8XXM	Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. Deposit date: 2024-01-18 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 2024
8W8E	human co-transcriptional RNA capping enzyme RNGTT Descriptor: DNA (36-MER), DNA (45-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Li, Y, Wang, Q, Xu, Y, Li, Z. Deposit date: 2023-09-02 Release date: 2024-04-10 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Strcutures of co-transcriptional RNA capping enzymes on paused transcription complex To Be Published
8V87	60S ribosome biogenesis intermediate (Dbp10 post-catalytic structure - Overall map) Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... Authors: Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. Deposit date: 2023-12-04 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (2.66 Å) Cite: The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
8V84	60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... Authors: Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. Deposit date: 2023-12-04 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
8V83	60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) Descriptor: 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... Authors: Cruz, V.E, Weirich, C.S, Peddada, N, Erzberger, J.P. Deposit date: 2023-12-04 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (2.53 Å) Cite: The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun, 15, 2024
8UI0	Structure of poised transcription complex Pol II-DSIF-NELF - pre-translocated Descriptor: DNA, DNA (38-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Vos, S.M, Su, B.G. Deposit date: 2023-10-09 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 2024
8UHG	Structure of paused transcription complex Pol II-DSIF-NELF - poised post-translocated Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... Authors: Vos, S.M, Su, B.G. Deposit date: 2023-10-09 Release date: 2024-03-20 Last modified: 2024-04-17 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 84, 2024
8UHD	Structure of paused transcription complex Pol II-DSIF-NELF - post-translocated Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB7, ... Authors: Su, B.G, Vos, S.M. Deposit date: 2023-10-08 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 2024
8UHA	Structure of paused transcription complex Pol II-DSIF-NELF - tilted Descriptor: DNA (28-MER), DNA (38-MER), DNA-directed RNA polymerase II subunit E, ... Authors: Vos, S.M, Su, B.G. Deposit date: 2023-10-08 Release date: 2024-03-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Distinct negative elongation factor conformations regulate RNA polymerase II promoter-proximal pausing. Mol.Cell, 2024
8SGH	Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS Descriptor: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1 Authors: Gonzalez, A, Fung, H.Y.J, Chook, Y.M. Deposit date: 2023-04-12 Release date: 2023-06-14 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders. Structure, 31, 2023
8RZV	Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA Descriptor: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-02-13 Release date: 2024-03-13 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA To Be Published
8QXB	TDP-43 amyloid fibrils: Morphology-2 Descriptor: TAR DNA-binding protein 43 Authors: Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M. Deposit date: 2023-10-24 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.86 Å) Cite: Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils. Nat Commun, 15, 2024
8QXA	TDP-43 amyloid fibrils: Morphology-1b Descriptor: TAR DNA-binding protein 43 Authors: Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M. Deposit date: 2023-10-24 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (4.05 Å) Cite: Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils. Nat Commun, 15, 2024
8QX9	TDP-43 amyloid fibrils: Morphology-1a Descriptor: TAR DNA-binding protein 43 Authors: Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M. Deposit date: 2023-10-24 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.76 Å) Cite: Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils. Nat Commun, 15, 2024
8QO9	Cryo-EM structure of a human spliceosomal B complex protomer Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. Deposit date: 2023-09-28 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (5.29 Å) Cite: New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes To Be Published
8PX5	Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe., solved at wavelength 2.75 A Descriptor: Rpb7-binding protein seb1 Authors: El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Wittmann, S, Renner, M, Grimes, J.M, Wagner, A. Deposit date: 2023-07-22 Release date: 2023-10-25 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Experimental phasing opportunities for macromolecular crystallography at very long wavelengths. Commun Chem, 6, 2023
8PVL	Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite structure Descriptor: 26S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. Deposit date: 2023-07-17 Release date: 2023-12-06 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (2.19 Å) Cite: Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
8PVK	Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite structure Descriptor: 26S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. Deposit date: 2023-07-17 Release date: 2023-12-06 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (2.55 Å) Cite: Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
8PV7	Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite structure Descriptor: 26S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. Deposit date: 2023-07-17 Release date: 2023-11-15 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (2.12 Å) Cite: Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
8PV6	Chaetomium thermophilum pre-60S State 3 - post-5S rotation with Rix1 complex with Foot - composite structure Descriptor: 26S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. Deposit date: 2023-07-17 Release date: 2023-11-15 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (2.94 Å) Cite: Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
8PV4	Chaetomium thermophilum pre-60S State 2 - pre-5S rotation with Rix1 complex - composite structure Descriptor: 26S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. Deposit date: 2023-07-17 Release date: 2023-11-15 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023

 

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