6J6Q
| Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2019-01-15 | Release date: | 2019-04-24 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6J6N
| Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | Authors: | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2019-01-15 | Release date: | 2019-04-24 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6J6H
| Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom | Descriptor: | ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2019-01-15 | Release date: | 2019-04-24 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6J6G
| Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom | Descriptor: | ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | Authors: | Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. | Deposit date: | 2019-01-15 | Release date: | 2019-04-24 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
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6ID1
| Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6ID0
| Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6ICZ
| Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6HPJ
| Structure of human SRSF1 RRM1 bound to AACAAA RNA | Descriptor: | Immunoglobulin G-binding protein G,Serine/arginine-rich splicing factor 1, RNA (5'-R(*AP*AP*CP*AP*AP*A)-3') | Authors: | Allain, F.T.H, Clery, A. | Deposit date: | 2018-09-21 | Release date: | 2020-11-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing. Nat Commun, 12, 2021
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6HIP
| Structure of SPF45 UHM bound to HIV-1 Rev ULM | Descriptor: | HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ... | Authors: | Pabis, M, Corsini, L, Sattler, M. | Deposit date: | 2018-08-30 | Release date: | 2019-03-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors. Nucleic Acids Res., 47, 2019
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6GX6
| Crystal structure of IMP3 RRM12 in complex with RNA (ACAC) | Descriptor: | 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3, PHOSPHATE ION, ... | Authors: | Jia, M, Gut, H, Chao, A.J. | Deposit date: | 2018-06-26 | Release date: | 2018-09-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of IMP3 RRM12 recognition of RNA. RNA, 24, 2018
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6GSN
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6GSM
| Structure of a partial yeast 48S preinitiation complex in open conformation. | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2018-06-14 | Release date: | 2019-07-31 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (5.15 Å) | Cite: | Large-scale movement of eIF3 domains during translation initiation modulate start codon selection. Nucleic Acids Res., 2021
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6GML
| Structure of paused transcription complex Pol II-DSIF-NELF | Descriptor: | DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Vos, S.M, Farnung, L, Urlaub, H, Cramer, P. | Deposit date: | 2018-05-27 | Release date: | 2018-09-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of paused transcription complex Pol II-DSIF-NELF. Nature, 560, 2018
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6GD3
| Structure of HuR RRM3 in complex with RNA (UAUUUA) | Descriptor: | ELAV-like protein 1, RNA (5'-R(P*UP*AP*UP*UP*UP*A)-3'), SODIUM ION | Authors: | Pabis, M, Sattler, M. | Deposit date: | 2018-04-21 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs. Nucleic Acids Res., 47, 2019
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6GD2
| Structure of HuR RRM3 in complex with RNA | Descriptor: | ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*AP*UP*UP*U)-3') | Authors: | Pabis, M, Sattler, M. | Deposit date: | 2018-04-21 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs. Nucleic Acids Res., 47, 2019
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6GD1
| Structure of HuR RRM3 | Descriptor: | SODIUM ION, Thioredoxin 1,ELAV-like protein 1 | Authors: | Pabis, M, Sattler, M. | Deposit date: | 2018-04-21 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs. Nucleic Acids Res., 47, 2019
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6GC5
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6GBM
| Solution structure of FUS-RRM bound to stem-loop RNA | Descriptor: | RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3'), RNA-binding protein FUS | Authors: | Loughlin, F.E, Allain, F.H.-T. | Deposit date: | 2018-04-15 | Release date: | 2019-02-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity. Mol. Cell, 73, 2019
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6G90
| Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2) | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing factor 39, ... | Authors: | Plaschka, C, Lin, P.-C, Charenton, C, Nagai, K. | Deposit date: | 2018-04-10 | Release date: | 2018-08-22 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Prespliceosome structure provides insights into spliceosome assembly and regulation. Nature, 559, 2018
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6G2K
| Structure of HuR RRM3 in complex with RNA (UUUUUU) | Descriptor: | ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), SULFATE ION | Authors: | Pabis, M, Sattler, M. | Deposit date: | 2018-03-23 | Release date: | 2018-10-31 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs. Nucleic Acids Res., 47, 2019
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6FYY
| Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2018-03-12 | Release date: | 2018-12-05 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
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6FYX
| Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1) | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... | Authors: | Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. | Deposit date: | 2018-03-12 | Release date: | 2018-12-05 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
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6FQR
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6FQ1
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6FF7
| human Bact spliceosome core structure | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | Authors: | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | Deposit date: | 2018-01-03 | Release date: | 2019-03-13 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex. Cell, 172, 2018
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