6ID1

Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution

Summary for 6ID1

• Entry DOI: 10.2210/pdb6id1/pdb
• EMDB information: 9647
• Descriptor: Pre-mRNA-processing-splicing factor 8, Pre-mRNA-splicing factor RBM22, Spliceosome-associated protein CWC15 homolog, ... (37 entities in total)
• Functional Keywords: human intron lariat spliceosome, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 43
• Total formula weight: 2147516.59

Authors

Zhang, X.,Zhan, X.,Yan, C.,Shi, Y. (deposition date: 2018-09-07, release date: 2019-03-13, Last modification date: 2020-10-14)

• Primary citation: Zhang, X.,Zhan, X.,Yan, C.,Zhang, W.,Liu, D.,Lei, J.,Shi, Y.; Structures of the human spliceosomes before and after release of the ligated exon.; Cell Res., 29:274-285, 2019; PubMed: 30728453; DOI: 10.1038/s41422-019-0143-x

Experimental method

ELECTRON MICROSCOPY (2.86 Å)