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5YHN
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Solution structure of the LEKTI Domain 4
Descriptor: cDNA FLJ60407, highly similar to Serine protease inhibitor Kazal-type 5
Authors:Mok, Y.K, Ramesh, K.
Deposit date:2017-09-29
Release date:2018-08-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Homologous Lympho-Epithelial Kazal-type Inhibitor Domains Delay Blood Coagulation by Inhibiting Factor X and XI with Differential Specificity.
Structure, 26, 2018
6KBR
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BU of 6kbr by Molmil
Crystal structure of Human KLK4 and SPINK2 derived KLK4 inhibitor complex
Descriptor: GLYCEROL, K41043, Kallikrein-4
Authors:Kawaguchi, Y, Nishimiya, D.
Deposit date:2019-06-26
Release date:2019-07-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases.
Sci Rep, 9, 2019
7E50
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BU of 7e50 by Molmil
Crystal structure of human microplasmin in complex with kazal-type inhibitor AaTI
Descriptor: AAEL006007-PA, GLYCEROL, Plasminogen, ...
Authors:Varsha, A.W, Jobichen, C, Mok, Y.K.
Deposit date:2021-02-16
Release date:2022-02-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of Aedes aegypti trypsin inhibitor in complex with mu-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor.
Protein Sci., 31, 2022
7QE8
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Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 (SPINK1)
Descriptor: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
Authors:Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
Deposit date:2021-12-01
Release date:2022-03-30
Last modified:2022-04-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
7QE9
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Human cationic trypsin (TRY1) complexed with serine protease inhibitor Kazal type 1 N34S (SPINK1 N34S)
Descriptor: SULFATE ION, Serine protease inhibitor Kazal-type 1, Trypsin-1
Authors:Nagel, F, Palm, G.J, Delcea, M, Lammers, M.
Deposit date:2021-12-01
Release date:2022-03-30
Last modified:2022-04-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin.
Int J Mol Sci, 23, 2022
8S9P
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BU of 8s9p by Molmil
1:1:1 agrin/LRP4/MuSK complex
Descriptor: Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ...
Authors:Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C.
Deposit date:2023-03-29
Release date:2023-05-17
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
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