4I5Z
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4IDW
| Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure Refinement Strategy | Descriptor: | Insulin A chain, Insulin B chain, ZINC ION | Authors: | Margiolaki, I, Giannopoulou, A.E, Wright, J.P, Knight, L, Norrman, M, Schluckebier, G, Fitch, A, Von Dreele, R.B. | Deposit date: | 2012-12-13 | Release date: | 2013-06-05 | Method: | POWDER DIFFRACTION | Cite: | High-resolution powder X-ray data reveal the T6 hexameric form of bovine insulin Acta Crystallogr.,Sect.D, 69, 2013
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4IHN
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4INS
| THE STRUCTURE OF 2ZN PIG INSULIN CRYSTALS AT 1.5 ANGSTROMS RESOLUTION | Descriptor: | INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION | Authors: | Dodson, G.G, Dodson, E.J, Hodgkin, D.C, Isaacs, N.W, Vijayan, M. | Deposit date: | 1989-07-10 | Release date: | 1990-04-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The structure of 2Zn pig insulin crystals at 1.5 A resolution. Philos.Trans.R.Soc.London,Ser.B, 319, 1988
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4IUZ
| High resolution crystal structure of racemic ester insulin | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin A chain, ... | Authors: | Avital-Shmilovici, M, Mandal, K, Gates, Z.P, Phillips, N, Weiss, M.A, Kent, S.B.H. | Deposit date: | 2013-01-22 | Release date: | 2013-02-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
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4IYD
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4IYF
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4M4F
| Radiation damage study of Cu T6-insulin - 0.01 MGy | Descriptor: | COPPER (II) ION, Insulin | Authors: | Frankaer, C.G, Harris, P, Stahl, K. | Deposit date: | 2013-08-07 | Release date: | 2014-01-15 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr.,Sect.D, 70, 2014
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4M4H
| Radiation damage study of Cu T6-insulin - 0.06 MGy | Descriptor: | COPPER (II) ION, Insulin | Authors: | Frankaer, C.G, Harris, P, Stahl, K. | Deposit date: | 2013-08-07 | Release date: | 2014-01-15 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr.,Sect.D, 70, 2014
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4M4I
| Radiation damage study of Cu T6-insulin - 0.12 MGy | Descriptor: | COPPER (II) ION, Insulin | Authors: | Frankaer, C.G, Harris, P, Stahl, K. | Deposit date: | 2013-08-07 | Release date: | 2014-01-15 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr.,Sect.D, 70, 2014
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4M4J
| Radiation damage study of Cu T6-insulin - 0.30 MGy | Descriptor: | COPPER (II) ION, Insulin | Authors: | Frankaer, C.G, Harris, P, Stahl, K. | Deposit date: | 2013-08-07 | Release date: | 2014-01-15 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr.,Sect.D, 70, 2014
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4M4L
| The structure of Cu T6 bovine insulin | Descriptor: | COPPER (II) ION, Insulin | Authors: | Frankaer, C.G, Harris, P, Stahl, K. | Deposit date: | 2013-08-07 | Release date: | 2014-01-15 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr.,Sect.D, 70, 2014
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4M4M
| The structure of Ni T6 bovine insulin | Descriptor: | Insulin, NICKEL (II) ION | Authors: | Frankaer, C.G, Harris, P, Stahl, K. | Deposit date: | 2013-08-07 | Release date: | 2014-01-15 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Towards accurate structural characterization of metal centres in protein crystals: the structures of Ni and Cu T6 bovine insulin derivatives. Acta Crystallogr.,Sect.D, 70, 2014
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4NIB
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4OGA
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4P65
| Crystal structure of an cyclohexylalanine substituted insulin analog. | Descriptor: | CHLORIDE ION, Insulin, PHENOL, ... | Authors: | Pandyarajan, V, Wan, Z, Weiss, M.A. | Deposit date: | 2014-03-21 | Release date: | 2014-10-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Aromatic Anchor at an Invariant Hormone-Receptor Interface: FUNCTION OF INSULIN RESIDUE B24 WITH APPLICATION TO PROTEIN DESIGN. J.Biol.Chem., 289, 2014
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4RXW
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4UNE
| Human insulin B26Phe mutant crystal structure | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION | Authors: | Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. | Deposit date: | 2014-05-28 | Release date: | 2014-10-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
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4UNG
| Human insulin B26Asn mutant crystal structure | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION | Authors: | Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. | Deposit date: | 2014-05-28 | Release date: | 2014-10-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
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4UNH
| Human insulin B26Gly mutant crystal structure | Descriptor: | INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION | Authors: | Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M. | Deposit date: | 2014-05-28 | Release date: | 2014-10-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex Acta Crystallogr.,Sect.D, 70, 2014
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4XC4
| Insulin co-crystallizes in the presence of it beta-cell chaperone sulfatide | Descriptor: | CHLORIDE ION, Insulin, SODIUM ION, ... | Authors: | Bracey, A.W, Magis, A.T, Buschard, K, Osterbye, T, Bailey, K.M, Ostrov, D.A. | Deposit date: | 2014-12-17 | Release date: | 2015-02-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | Insulin co-crystallizes in the presence of it beta-cell chaperone sulfatide To Be Published
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4XSS
| Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... | Authors: | Lawrence, C, Kong, G.K.-W, Menting, J.G, Lawrence, M.C. | Deposit date: | 2015-01-22 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors. Structure, 23, 2015
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5AIY
| R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 'RED' SUBSTATE, AVERAGE STRUCTURE | Descriptor: | PHENOL, PROTEIN (INSULIN) | Authors: | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | Deposit date: | 1998-12-29 | Release date: | 2000-02-28 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure. J.Biomol.NMR, 16, 2000
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5AZZ
| Crystal structure of seleno-insulin | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Watanabe, S, Okumura, M, Arai, K, Takei, T, Asahina, Y, Hojo, H, Iwaoka, M, Inaba, K. | Deposit date: | 2015-10-23 | Release date: | 2017-05-03 | Last modified: | 2017-06-14 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue. Angew. Chem. Int. Ed. Engl., 56, 2017
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5BOQ
| Human insulin with intra-chain chemical crosslink between modified B24 and B29 | Descriptor: | Insulin, SULFATE ION | Authors: | Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. | Deposit date: | 2015-05-27 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Rational steering of insulin binding specificity by intra-chain chemical crosslinking. Sci Rep, 6, 2016
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