7Y4N
| Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos | Descriptor: | Growth factor receptor-bound protein 2 | Authors: | Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y. | Deposit date: | 2022-06-15 | Release date: | 2022-08-31 | Method: | SOLUTION NMR | Cite: | Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos. Biochem.Biophys.Res.Commun., 625, 2022
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5L23
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7NET
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7NES
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7NER
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7YXW
| Structure of the p22phox A200G mutant in complex with p47phox peptide | Descriptor: | Cytochrome b-245 light chain, Neutrophil cytosol factor 1 | Authors: | Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z. | Deposit date: | 2022-02-16 | Release date: | 2022-03-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics Acs Med.Chem.Lett., 13, 2022
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7NZC
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5NP3
| Abl2 SH3 | Descriptor: | Abelson tyrosine-protein kinase 2 | Authors: | Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. | Deposit date: | 2017-04-13 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
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5NP5
| Abl2 SH3 pTyr116/161 | Descriptor: | Abelson tyrosine-protein kinase 2, SULFATE ION | Authors: | Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. | Deposit date: | 2017-04-13 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
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4EIK
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8CHH
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8CF4
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8CHG
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7TZK
| EPS8 SH3 Domain with NleH1 PxxDY Motif | Descriptor: | Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog | Authors: | Grishin, A.M, Cygler, M. | Deposit date: | 2022-02-15 | Release date: | 2022-07-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli Proc.Natl.Acad.Sci.USA, 119, 2022
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7TPB
| p120RasGAP SH3 domain in complex with DLC1 RhoGAP domain | Descriptor: | Ras GTPase-activating protein 1, Rho GTPase-activating protein 7 | Authors: | Stiegler, A.L, Boggon, T.J, Chau, J.E, Vish, K.J. | Deposit date: | 2022-01-25 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP. Nat Commun, 13, 2022
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2F2W
| alpha-spectrin SH3 domain R21A mutant | Descriptor: | SULFATE ION, Spectrin alpha chain, brain | Authors: | Camara-Artigas, A, Conejero-Lara, F, Casares, S, Lopez-Mayorga, O, Vega, C. | Deposit date: | 2005-11-18 | Release date: | 2006-10-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain Proteins, 67, 2007
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2F2X
| alpha-spectrin SH3 domain R21G mutant | Descriptor: | SULFATE ION, Spectrin alpha chain, brain | Authors: | Camara-Artigas, A, Conejero-Lara, F, Casares, S, Lopez-Mayorga, O, Vega, C. | Deposit date: | 2005-11-18 | Release date: | 2006-10-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cooperative propagation of local stability changes from low-stability and high-stability regions in a SH3 domain Proteins, 67, 2007
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2EW3
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7CFZ
| SH3 domain of NADPH oxidase activator 1 | Descriptor: | NADPH oxidase activator 1 | Authors: | Kim, M, Park, J.H, Attri, P, Lee, W. | Deposit date: | 2020-06-29 | Release date: | 2021-07-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural modification of NADPH oxidase activator (Noxa 1) by oxidative stress: An experimental and computational study. Int.J.Biol.Macromol., 163, 2020
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2FRY
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3SEM
| SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR | Descriptor: | SEX MUSCLE ABNORMAL PROTEIN 5, SH3 PEPTOID INHIBITOR | Authors: | Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. | Deposit date: | 1998-11-02 | Release date: | 1999-01-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
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2YT6
| Solution structure of the SH3_1 domain of Yamaguchi sarcoma viral (v-yes) oncogene homolog 1 | Descriptor: | Adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530076O17 product:Yamaguchi sarcoma viral (v-yes) oncogene homolog | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2008-04-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the SH3_1 domain of Yamaguchi sarcoma viral (v-yes) oncogene homolog 1 To be Published
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2YUO
| Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3 | Descriptor: | RUN and TBC1 domain containing 3 | Authors: | Abe, H, Tochio, N, Miyamoto, K, Saito, K, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-06 | Release date: | 2007-10-09 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the SH3 domain of mouse RUN and TBC1 domain containing 3 To be Published
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5ZAU
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3H0H
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