7TZK
EPS8 SH3 Domain with NleH1 PxxDY Motif
Summary for 7TZK
| Entry DOI | 10.2210/pdb7tzk/pdb |
| Descriptor | Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog (3 entities in total) |
| Functional Keywords | nleh kinase, protein-protein interaction, sh3 domain, protein binding |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 17405.47 |
| Authors | Grishin, A.M.,Cygler, M. (deposition date: 2022-02-15, release date: 2022-07-06, Last modification date: 2023-10-18) |
| Primary citation | Pollock, G.L.,Grishin, A.M.,Giogha, C.,Gan, J.,Oates, C.V.,McMillan, P.J.,Gaeta, I.,Tyska, M.J.,Pearson, J.S.,Scott, N.E.,Cygler, M.,Hartland, E.L. Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli Proc.Natl.Acad.Sci.USA, 119:e2204332119-e2204332119, 2022 Cited by PubMed: 35976880DOI: 10.1073/pnas.2204332119 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.43 Å) |
Structure validation
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