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8A8V	Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide Authors: Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. Deposit date: 2022-06-24 Release date: 2022-10-26 Last modified: 2022-11-23 Method: ELECTRON MICROSCOPY (3.34 Å) Cite: Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
8A8U	Mycobacterium tuberculosis ClpC1 hexamer structure Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide Authors: Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. Deposit date: 2022-06-24 Release date: 2022-10-26 Last modified: 2022-11-23 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
8A8W	Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide Authors: Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. Deposit date: 2022-06-24 Release date: 2022-10-26 Last modified: 2022-11-23 Method: ELECTRON MICROSCOPY (4.29 Å) Cite: Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
8AMZ	Spinach 19S proteasome Descriptor: 26S proteasome non-ATPase regulatory subunit 1 homolog, 26S proteasome non-ATPase regulatory subunit 2 homolog, 26S proteasome regulatory subunit 7, ... Authors: Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D. Deposit date: 2022-08-04 Release date: 2022-08-24 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Cryo-EM structure of the plant 26S proteasome Plant Communications, 3, 2022
8B5R	p97-p37-SPI substrate complex Descriptor: I3 sequence being threaded through the p97 channel, Protein phosphatase 1 regulatory subunit 7, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, ... Authors: van den Boom, J, Marini, G, Meyer, H, Saibil, H. Deposit date: 2022-09-24 Release date: 2023-06-07 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Structural basis of ubiquitin-independent PP1 complex disassembly by p97. Embo J., 42, 2023
8C0V	Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in single seam state Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Ruettermann, M, Koci, M, Lill, P, Geladas, E.D, Kaschani, F, Klink, B.U, Erdmann, R, Gatsogiannis, C. Deposit date: 2022-12-19 Release date: 2023-10-04 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate. Nat Commun, 14, 2023
8C0W	Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in twin seam state Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Ruettermann, M, Koci, M, Lill, P, Geladas, E.D, Kaschani, F, Klink, B.U, Erdmann, R, Gatsogiannis, C. Deposit date: 2022-12-19 Release date: 2023-10-04 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate. Nat Commun, 14, 2023
8CVT	Human 19S-20S proteasome, state SD2 Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Zhao, J. Deposit date: 2022-05-18 Release date: 2022-11-02 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
8D6X	Structure of the Mycobacterium tuberculosis 20S proteasome bound to the ATP-bound Mpa ATPase Descriptor: AAA ATPase forming ring-shaped complexes, Proteasome subunit alpha, Proteasome subunit beta, ... Authors: Xiao, X, Li, H. Deposit date: 2022-06-06 Release date: 2022-08-03 Last modified: 2022-11-09 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The beta-Grasp Domain of Proteasomal ATPase Mpa Makes Critical Contacts with the Mycobacterium tuberculosis 20S Core Particle to Facilitate Degradation. Msphere, 7, 2022
8D6Y	Structure of the Mycobacterium tuberculosis 20S proteasome bound to the ADP-bound Mpa ATPase Descriptor: AAA ATPase forming ring-shaped complexes, Proteasome subunit alpha, Proteasome subunit beta, ... Authors: Xiao, X, Li, H. Deposit date: 2022-06-06 Release date: 2022-08-03 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (10 Å) Cite: The beta-Grasp Domain of Proteasomal ATPase Mpa Makes Critical Contacts with the Mycobacterium tuberculosis 20S Core Particle to Facilitate Degradation. Msphere, 7, 2022
8DAR	Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex unbound but in the presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ... Authors: Lee, H.G, Lima, C.D. Deposit date: 2022-06-14 Release date: 2022-11-30 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3 Å) Cite: SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8DAU	Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two folded ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (uA) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ... Authors: Lee, H.G, Lima, C.D. Deposit date: 2022-06-14 Release date: 2022-11-30 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8DAW	Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 2 (uD) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ... Authors: Lee, H.G, Lima, C.D. Deposit date: 2022-06-14 Release date: 2022-11-30 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8DAS	Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two ubiquitin moieties in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (intA) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ... Authors: Lee, H.G, Lima, C.D. Deposit date: 2022-06-14 Release date: 2022-11-30 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8DAT	Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (intB) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ... Authors: Lee, H.G, Lima, C.D. Deposit date: 2022-06-14 Release date: 2022-11-30 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8DAV	Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 2 (uC) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ... Authors: Lee, H.G, Lima, C.D. Deposit date: 2022-06-14 Release date: 2022-11-30 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex. Proc.Natl.Acad.Sci.USA, 120, 2023
8DR3	Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD Descriptor: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ... Authors: Schrecker, M, Hite, R.K. Deposit date: 2022-07-20 Release date: 2022-08-17 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8DR4	Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) without NTD Descriptor: DNA (5'-D(P*AP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... Authors: Schrecker, M, Hite, R.K. Deposit date: 2022-07-20 Release date: 2022-08-17 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.45 Å) Cite: Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8DR7	Open state of RFC:PCNA bound to a nicked dsDNA Descriptor: DNA (26-MER), DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... Authors: Schrecker, M, Hite, R.K. Deposit date: 2022-07-20 Release date: 2022-08-17 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8DR5	Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD Descriptor: DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... Authors: Schrecker, M, Hite, R.K. Deposit date: 2022-07-20 Release date: 2022-08-17 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8DQW	Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction Descriptor: DDC1 isoform 1, DNA (5'-D(P*CP*GP*TP*CP*CP*CP*TP*TP*CP*C)-3'), DNA (50-MER), ... Authors: Schrecker, M, Hite, R.K. Deposit date: 2022-07-20 Release date: 2022-08-17 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8DR1	Consensus closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) Descriptor: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ... Authors: Schrecker, M, Hite, R.K. Deposit date: 2022-07-20 Release date: 2022-08-17 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.14 Å) Cite: Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8DQX	Open state of RFC:PCNA bound to a 3' ss/dsDNA junction Descriptor: DNA (5'-D(*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*CP*CP*GP*AP*GP*CP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*GP*CP*CP*CP*GP*GP*A)-3'), ... Authors: Schrecker, M, Hite, R.K. Deposit date: 2022-07-20 Release date: 2022-08-24 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.1 Å) Cite: Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8DR0	Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction Descriptor: DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ... Authors: Schrecker, M, Hite, R.K. Deposit date: 2022-07-20 Release date: 2022-08-24 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.42 Å) Cite: Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022
8DQZ	Intermediate state of RFC:PCNA bound to a 3' ss/dsDNA junction Descriptor: DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ... Authors: Schrecker, M, Hite, R.K. Deposit date: 2022-07-20 Release date: 2022-08-24 Last modified: 2024-02-14 Method: ELECTRON MICROSCOPY (2.92 Å) Cite: Multistep loading of a DNA sliding clamp onto DNA by replication factor C. Elife, 11, 2022

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