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5XGG	Crystal Structure C-terminal SH3 domain of Myosin IB from Entamoeba histolytica Descriptor: SULFATE ION, Unconventional myosin IB Authors: Gautam, G, Gourinath, S. Deposit date: 2017-04-13 Release date: 2017-08-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition Acta Crystallogr D Struct Biol, 73, 2017
1AZE	NMR STRUCTURE OF THE COMPLEX BETWEEN THE C32S-Y7V MUTANT OF THE NSH3 DOMAIN OF GRB2 WITH A PEPTIDE FROM SOS, 10 STRUCTURES Descriptor: GRB2, SOS Authors: Vidal, M, Gincel, E, Goudreau, N, Cornille, F, Parker, F, Duchesne, M, Tocque, B, Garbay, C, Roques, B.P. Deposit date: 1997-11-17 Release date: 1999-05-18 Last modified: 2021-11-03 Method: SOLUTION NMR Cite: Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin. J.Mol.Biol., 290, 1999
1AZG	NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE Descriptor: FYN, PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR Authors: Renzoni, D.A, Pugh, D.J.R, Siligardi, G, Das, P, Morton, C.J, Rossi, C, Waterfield, M.D, Campbell, I.D, Ladbury, J.E. Deposit date: 1997-11-18 Release date: 1998-02-25 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase. Biochemistry, 35, 1996
1AWO	THE SOLUTION NMR STRUCTURE OF ABL SH3 AND ITS RELATIONSHIP TO SH2 IN THE SH(32) CONSTRUCT, 20 STRUCTURES Descriptor: ABL TYROSINE KINASE Authors: Cowburn, D. Deposit date: 1997-10-03 Release date: 1998-01-28 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct. Structure, 3, 1995
1AWX	SH3 DOMAIN FROM BRUTON'S TYROSINE KINASE, NMR, MINIMIZED AVERAGE STRUCTURE Descriptor: BRUTON'S TYROSINE KINASE Authors: Hansson, H, Mattsson, P.T, Allard, P, Haapaniemi, P, Vihinen, M, Smith, C.I.E, Hard, T. Deposit date: 1997-10-06 Release date: 1998-04-08 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Solution structure of the SH3 domain from Bruton's tyrosine kinase. Biochemistry, 37, 1998
5XG9	Crystal Structure of PEG-bound SH3 domain of Myosin IB from Entamoeba histolytica Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, PENTAETHYLENE GLYCOL, ... Authors: Gautam, G, Gourinath, S. Deposit date: 2017-04-13 Release date: 2017-08-16 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition Acta Crystallogr D Struct Biol, 73, 2017
1AOJ	THE SH3 DOMAIN OF EPS8 EXISTS AS A NOVEL INTERTWINED DIMER Descriptor: EPS8 Authors: Kishan, K.V.R, Newcomer, M.E. Deposit date: 1997-07-07 Release date: 1998-07-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The SH3 domain of Eps8 exists as a novel intertwined dimer. Nat.Struct.Biol., 4, 1997
1BU1	SRC FAMILY KINASE HCK SH3 DOMAIN Descriptor: PROTEIN (HEMOPOIETIC CELL KINASE) Authors: Arold, S, Franken, P, Dumas, C. Deposit date: 1998-09-09 Release date: 1998-11-11 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.6 Å) Cite: RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef. Biochemistry, 37, 1998
1BK2	A-SPECTRIN SH3 DOMAIN D48G MUTANT Descriptor: A-SPECTRIN Authors: Martinez, J.C, Pisabarro, M.T, Serrano, L. Deposit date: 1998-07-14 Release date: 1999-02-16 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Obligatory steps in protein folding and the conformational diversity of the transition state. Nat.Struct.Biol., 5, 1998
4QT7	Crystal structure of the c-Src SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein Descriptor: NS5A, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-07-07 Release date: 2014-12-24 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Structure of the c-Src-SH3 domain in complex with a proline-rich motif of NS5A protein from the hepatitis C virus. J.Struct.Biol., 189, 2015
4RTT	Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment Descriptor: SLIT-ROBO Rho GTPase-activating protein 2, SULFATE ION Authors: Opatowsky, Y, Guez-Hadad, J. Deposit date: 2014-11-16 Release date: 2015-11-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.87 Å) Cite: The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism. Structure, 23, 2015
4RTY	Crystal structure of the c-Src-SH3 domain in complex with the high affinity peptide APP12 Descriptor: APP12 peptide, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-11-16 Release date: 2015-10-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.279 Å) Cite: Crystal structure of the c-Src-SH3 domain in complex with the high affinity peptide APP12 To be Published
3C0C	X-ray Crystal Structure of the Rat Endophilin A2 SH3 Domain Descriptor: Endophilin-A2 Authors: Loll, P.J, Swain, E. Deposit date: 2008-01-19 Release date: 2008-03-18 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of the SH3 domain of rat endophilin A2 To be Published
4RTV	Crystal structure of the Src tyrosine kinase SH3 domain S94A/Q128R mutant in complex with the high affinity synthetic peptide APP12 Descriptor: APP12 peptide, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-11-16 Release date: 2015-10-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Crystal structure of the Src tyrosine kinase SH3 domain S94A/Q128R mutant in complex with the high affinity synthetic peptide APP12 To be Published
4RTX	Crystal structure of the Src tyrosine kinase SH3 domain T96G/Q128R mutant Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src, ... Authors: Camara-Artigas, A. Deposit date: 2014-11-16 Release date: 2015-10-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.32 Å) Cite: Crystal structure of the Src tyrosine kinase SH3 domain T96G/Q128R mutant To be Published
4RUG	Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment Descriptor: SLIT-ROBO Rho GTPase-activating protein 2 Authors: Opatowsky, Y, Guez-Hadad, J. Deposit date: 2014-11-19 Release date: 2015-11-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.73 Å) Cite: The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism. Structure, 23, 2015
4RTU	Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T96G/Q128R mutant Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-11-16 Release date: 2015-10-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.453 Å) Cite: Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T96G/Q128R mutant To be Published
4RTW	Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12 Descriptor: APP12 peptide, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-11-16 Release date: 2015-10-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12 To be Published
4RTZ	Crystal structure of the c-Src-SH3 domain in complex with the high affinity peptide VSL12 Descriptor: GLYCEROL, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src, ... Authors: Camara-Artigas, A, Bacarizo, J. Deposit date: 2014-11-16 Release date: 2015-10-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (0.979 Å) Cite: Crystal structure of the c-Src-SH3 domain in complex with the high affinity peptide VSL12 To be Published
5ZAU	Complex of the human FYN SH3 and monobody binder Descriptor: Monobody Binder, Tyrosine-protein kinase Fyn Authors: Reddy, P.P, Gulyani, A, Das, R. Deposit date: 2018-02-09 Release date: 2019-09-11 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells. Elife, 9, 2020
3CQT	N53I V55L MUTANT of FYN SH3 DOMAIN Descriptor: Proto-oncogene tyrosine-protein kinase Fyn Authors: Neculai, A.M, Zarrine-Afsar, A, Howell, P.L, Davidson, A, Chan, H.S. Deposit date: 2008-04-03 Release date: 2008-07-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding. Proc.Natl.Acad.Sci.Usa, 105, 2008
6A9C	Crystal Structure c-terminal SH3 domain of Myosin IB from Entamoeba histolytica bound to EhFP10(GEF) peptide. Descriptor: Peptide from Rho guanine nucleotide exchange factor, SULFATE ION, Unconventional myosin IB Authors: Gautam, G, Gourinath, S. Deposit date: 2018-07-13 Release date: 2019-06-12 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.98 Å) Cite: EhFP10: A FYVE family GEF interacts with myosin IB to regulate cytoskeletal dynamics during endocytosis in Entamoeba histolytica. Plos Pathog., 15, 2019
6ATV	The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions Descriptor: Adapter molecule crk, proline-rich motif in IAV-NS1 Authors: Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. Deposit date: 2017-08-29 Release date: 2018-08-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.751 Å) Cite: Molecular Mechanisms of Tight Binding through Fuzzy Interactions. Biophys. J., 114, 2018
3EG2	Crystal structure of the N114Q mutant of ABL-SH3 domain Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2008-09-10 Release date: 2009-09-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285, 2010
3EG1	Crystal structure of the N114Q mutant of ABL-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions Descriptor: Proto-oncogene tyrosine-protein kinase ABL1, SULFATE ION, p41 peptide Authors: Camara-Artigas, A. Deposit date: 2008-09-10 Release date: 2009-09-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. J.Biol.Chem., 285, 2010

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