1BU1
SRC FAMILY KINASE HCK SH3 DOMAIN
Summary for 1BU1
Entry DOI | 10.2210/pdb1bu1/pdb |
Descriptor | PROTEIN (HEMOPOIETIC CELL KINASE) (2 entities in total) |
Functional Keywords | tyrosine-protein kinase, transferase, signal transduction, sh3 |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Lysosome. Isoform 2: Cell membrane ; Lipid-anchor . Cytoplasmic vesicle, secretory vesicle: P08631 |
Total number of polymer chains | 6 |
Total formula weight | 39812.57 |
Authors | Arold, S.,Franken, P.,Dumas, C. (deposition date: 1998-09-09, release date: 1998-11-11, Last modification date: 2023-08-09) |
Primary citation | Arold, S.,O'Brien, R.,Franken, P.,Strub, M.P.,Hoh, F.,Dumas, C.,Ladbury, J.E. RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef. Biochemistry, 37:14683-14691, 1998 Cited by PubMed: 9778343DOI: 10.1021/bi980989q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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