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4EB4
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Crystal structure of mouse thymidylate synthase in ternary complex with dUMP and Tomudex
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Dowiercial, A, Jarmula, A, Rypniewski, W.R, Wilk, P, Rode, W.
Deposit date:2012-03-23
Release date:2012-05-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of mouse thymidylate synthase in tertiary complex with dUMP and raltitrexed reveals N-terminus architecture and two different active site conformations.
Biomed Res Int, 2014, 2014

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