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PDB: 5 results
8GJ4
A1 Tei: Adenylation domain 1 core construct from teicoplanin biosynthesis
Descriptor:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MbtH-like short polypeptide, ...
Authors:
Hansen, M.H
,
Cryle, M.J.
Deposit date:
2023-03-14
Release date:
2023-12-06
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.81 Å)
Cite:
Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
8GKM
A1 Leu graft + Leu: Adenylation domain 1 core construct from teicoplanin biosynthesis, leucine selection pocket graft; leucine bound
Descriptor:
ACETIC ACID, DI(HYDROXYETHYL)ETHER, LEUCINE, ...
Authors:
Hansen, M.H
,
Cryle, M.J.
Deposit date:
2023-03-20
Release date:
2023-12-06
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.89 Å)
Cite:
Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
8GJP
A1 Int graft: Adenylation domain 1 core construct from teicoplanin biosynthesis, intermediate selection pocket graft
Descriptor:
MbtH-like short polypeptide, Non-ribosomal peptide synthetase
Authors:
Hansen, M.H
,
Cryle, M.J.
Deposit date:
2023-03-16
Release date:
2023-12-06
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (2.7 Å)
Cite:
Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
8GIC
A1 Tei + Hpg: Adenylation domain 1 core construct from teicoplanin biosynthesis; 4-hydroxyphenylglycine bound
Descriptor:
(2S)-AMINO(4-HYDROXYPHENYL)ACETIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MbtH-like short polypeptide, ...
Authors:
Hansen, M.H
,
Cryle, M.J.
Deposit date:
2023-03-14
Release date:
2023-12-06
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (1.64 Å)
Cite:
Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
8GLC
A1 AncAla: Adenylation domain 1 core construct from ancestral reconstruction of glycopeptide antibiotic biosynthesis, alanine selection pocket
Descriptor:
MbtH-like short polypeptide, Non-ribosomal peptide synthetase
Authors:
Hansen, M.H
,
Cryle, M.J.
Deposit date:
2023-03-21
Release date:
2023-12-06
Last modified:
2023-12-13
Method:
X-RAY DIFFRACTION (3.12 Å)
Cite:
Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.
Nat Commun, 14, 2023
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221051
PDB entries from 2024-06-12