PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Crystal structure of ERK2 bound to (S)-N-(2-hydroxy-1-phenylethyl)-4-(5-methyl-2-(phenylamino)pyrimidin-4-yl)-1H-pyrrole-2-carboxamide
Descriptor:	Mitogen-activated protein kinase 1, N-[(1S)-2-hydroxy-1-phenylethyl]-4-[5-methyl-2-(phenylamino)pyrimidin-4-yl]-1H-pyrrole-2-carboxamide, SULFATE ION
Authors:	Jacobs, M.D, Xie, X.
Deposit date:	2009-07-06
Release date:	2010-01-12
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. J.Med.Chem., 52, 2009

Crystal structure of GSK3b in complex with a pyrimidylpyrrole inhibitor
Descriptor:	Glycogen synthase kinase-3 beta, N-[(1S)-2-hydroxy-1-phenylethyl]-4-[5-methyl-2-(phenylamino)pyrimidin-4-yl]-1H-pyrrole-2-carboxamide
Authors:	Ter Haar, E.
Deposit date:	2009-07-01
Release date:	2010-01-12
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. J.Med.Chem., 52, 2009

Crystal structure of ERK2 bound to (S)-4-(2-(2-chlorophenylamino)-5-methylpyrimidin-4-yl)-N-(2-hydroxy-1-phenylethyl)-1H-pyrrole-2-carboxamide
Descriptor:	4-{2-[(2-chlorophenyl)amino]-5-methylpyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-phenylethyl]-1H-pyrrole-2-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION
Authors:	Jacobs, M.D, Xie, X.
Deposit date:	2009-07-06
Release date:	2010-01-12
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. J.Med.Chem., 52, 2009