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PDB: 1 results

SIRT2(56-356) with covalent intermediate between mechanism-based inhibitor Glucose-TM-1beta and 1'-SH ADP-ribose
Descriptor:	GLYCEROL, NAD-dependent protein deacetylase sirtuin-2, N~2~-[3-(2-hydroxyethoxy)propanoyl]-N-phenyl-N~6~-tetradecanethioyl-L-lysinamide, ...
Authors:	Price, I.R, Hong, J.
Deposit date:	2019-01-22
Release date:	2020-01-22
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors. Acs Chem.Biol., 14, 2019