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PDB: 3 results

2EXL
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BU of 2exl by Molmil
GRP94 N-terminal Domain bound to geldanamycin
Descriptor: Endoplasmin, GELDANAMYCIN, PENTAETHYLENE GLYCOL, ...
Authors:Reardon, P.N, Immormino, R.M, Gewirth, D.T.
Deposit date:2005-11-08
Release date:2006-10-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
J.Mol.Biol., 388, 2009
2FXS
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BU of 2fxs by Molmil
Yeast HSP82 in complex with the novel HSP90 Inhibitor Radamide
Descriptor: ATP-dependent molecular chaperone HSP82, GLYCEROL, METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE
Authors:Immormino, R.M, Gewirth, D.T.
Deposit date:2006-02-06
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
J.Mol.Biol., 388, 2009
2GFD
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BU of 2gfd by Molmil
GRP94 in complex with the novel HSP90 Inhibitor Radamide
Descriptor: Endoplasmin, METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE, PENTAETHYLENE GLYCOL, ...
Authors:Immormino, R.M, Gewirth, D.T.
Deposit date:2006-03-21
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
J.Mol.Biol., 388, 2009

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