PDB: 1371 resultsInfo pagesStatus searchChemie searchBIRD

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5IRQ	Human cytochrome P450 17A1 bound to inhibitors (R)- and (S)- orteronel Descriptor: (R)-orteronel, (S)-orteronel, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Scott, E.E, Petrunak, E.M. Deposit date: 2016-03-14 Release date: 2017-03-15 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.202 Å) Cite: Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1. Drug Metab. Dispos., 45, 2017
5IUZ	STRUCTURE OF P450 2B4 F202W MUTANT (CYMAL-5) Descriptor: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE Authors: Jang, H.-H, Halpert, J.R, Shah, M.B. Deposit date: 2016-03-18 Release date: 2016-06-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.73 Å) Cite: Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry. Biophys.Chem., 216, 2016
5B2Y	Crystal Structure of P450BM3 with N-perfluorodecanoyl-L-tryptophan Descriptor: (2~{S})-3-(1~{H}-indol-3-yl)-2-[2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-nonadecakis(fluoranyl)decanoylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE Authors: Cong, Z, Shoji, O, Kasai, C, Sugimoto, H, Shiro, Y, Watanabe, Y. Deposit date: 2016-02-07 Release date: 2017-02-08 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Crystal Structure of P450BM3 with decoy molecules to be published
5B2U	Crystal Structure of P450BM3 with N-perfluorohexanoyl -L-tryptophan Descriptor: (2~{S})-3-(1~{H}-indol-3-yl)-2-[2,2,3,3,4,4,5,5,6,6,6-undecakis(fluoranyl)hexanoylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, DIMETHYL SULFOXIDE, ... Authors: Cong, Z, Shoji, O, Kasai, C, Sugimoto, H, Shiro, Y, Watanabe, Y. Deposit date: 2016-02-03 Release date: 2017-02-08 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structure of P450BM3 with decoy molecules to be published
5B2W	Crystal Structure of P450BM3 with N-perfluorododecanoyl-L-tryptophan Descriptor: (2~{S})-3-(1~{H}-indol-3-yl)-2-[2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-tricosakis(fluoranyl)dodecanoylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE Authors: Cong, Z, Shoji, O, Kasai, C, Sugimoto, H, Shiro, Y, Watanabe, Y. Deposit date: 2016-02-03 Release date: 2017-02-08 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal Structure of P450BM3 with decoy molecules to be published
8C9I	Cytochrome P450 CYP141A1 (Rv3121) from Mycobacterium tuberculosis Descriptor: Cytochrome P450 141, HEME B/C Authors: Selvam, I.R. Deposit date: 2023-01-23 Release date: 2024-02-07 Method: X-RAY DIFFRACTION (2.05 Å) Cite: 2.05 Angstrom structure of cytochrome P450 CYP141A1 (Rv3121) from Mycobacterium tuberculosis To Be Published
8CKN	Cytochrome P450 CYP143A1 (Rv1785c) from Mycobacterium tuberculosis Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Selvam, I.R. Deposit date: 2023-02-16 Release date: 2024-02-28 Method: X-RAY DIFFRACTION (1.54 Å) Cite: 1.54 Angstrom structure of cytochrome P450 CYP143A1 (Rv1785c) from Mycobacterium tuberculosis To Be Published
1P0V	F393A mutant heme domain of flavocytochrome P450 BM3 Descriptor: Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE Authors: Ost, T.W.B, Clark, J, Miles, C.S, Walkinshaw, M.D, Reid, G.A, Chapman, S.K, Daff, S, Mowat, C.G. Deposit date: 2003-04-11 Release date: 2003-12-09 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Oxygen Activation and Electron Transfer in Flavocytochrome P450 BM3 J.Am.Chem.Soc., 125, 2003
8DL4	S. CEREVISIAE CYP51 COMPLEXED WITH Courmarin-containing INHIBITOR Descriptor: 7-(diethylamino)-N-[(2S)-2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl]-2-oxo-2H-1-benzopyran-3-carboxamide, Lanosterol 14-alpha demethylase, PENTAETHYLENE GLYCOL, ... Authors: Ruma, Y.N, Keniya, M.V, Tyndall, J.D, Monk, B.C. Deposit date: 2022-07-06 Release date: 2022-08-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.91 Å) Cite: S. CEREVISIAE CYP51 COMPLEXED WITH Courmarin-containing INHIBITOR To Be Published
1PHC	CRYSTAL STRUCTURE OF SUBSTRATE-FREE PSEUDOMONAS PUTIDA CYTOCHROME P450 Descriptor: CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE Authors: Poulos, T.L. Deposit date: 1992-07-27 Release date: 1993-10-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of substrate-free Pseudomonas putida cytochrome P-450. Biochemistry, 25, 1986
1PHG	CRYSTAL STRUCTURES OF METYRAPONE-AND PHENYLIMIDAZOLE-INHIBITED COMPLEXES OF CYTOCHROME P450-CAM Descriptor: CYTOCHROME P450-CAM, METYRAPONE, PROTOPORPHYRIN IX CONTAINING FE Authors: Poulos, T.L. Deposit date: 1992-07-27 Release date: 1993-10-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam. Biochemistry, 26, 1987
1PHE	CRYSTAL STRUCTURES OF METYRAPONE-AND PHENYLIMIDAZOLE-INHIBITED COMPLEXES OF CYTOCHROME P450-CAM Descriptor: 2-phenyl-1H-imidazole, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Poulos, T.L. Deposit date: 1992-07-27 Release date: 1993-10-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam. Biochemistry, 26, 1987
1PHF	CRYSTAL STRUCTURES OF METYRAPONE-AND PHENYLIMIDAZOLE-INHIBITED COMPLEXES OF CYTOCHROME P450-CAM Descriptor: 4-PHENYL-1H-IMIDAZOLE, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE Authors: Poulos, T.L. Deposit date: 1992-07-27 Release date: 1993-10-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam. Biochemistry, 26, 1987
1PHB	INHIBITOR-INDUCED CONFORMATIONAL CHANGE IN CYTOCHROME P450-CAM Descriptor: 1-(N-IMIDAZOLYL)-2-HYDROXY-2-(2,3-DICHLOROPHENYL)OCTANE, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE Authors: Poulos, T.L. Deposit date: 1992-07-27 Release date: 1993-10-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Inhibitor-induced conformational change in cytochrome P-450CAM. Biochemistry, 32, 1993
1PHA	INHIBITOR-INDUCED CONFORMATIONAL CHANGE IN CYTOCHROME P450-CAM Descriptor: 1-(N-IMIDAZOLYL)-2-HYDROXY-2-(2,3-DICHLOROPHENYL)OCTANE, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE Authors: Poulos, T.L. Deposit date: 1992-07-27 Release date: 1993-10-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Inhibitor-induced conformational change in cytochrome P-450CAM. Biochemistry, 32, 1993
8D39	The crystal structure of WT CYP199A4 bound to 4-benzoylbenzoic acid Descriptor: 4-benzoylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... Authors: Podgorski, M.N, Bell, S.G. Deposit date: 2022-06-01 Release date: 2023-01-04 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.268 Å) Cite: Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry, 28, 2022
1PKF	Crystal Structure of Epothilone D-bound Cytochrome P450epoK Descriptor: EPOTHILONE D, PROTOPORPHYRIN IX CONTAINING FE, cytochrome p450EpoK Authors: Nagano, S, Li, H, Shimizu, H, Nishida, C, Ogura, H, Ortiz de Montellano, P.R, Poulos, T.L. Deposit date: 2003-06-05 Release date: 2003-10-28 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structures of Epothilone D-bound, Epothilone B-bound, and Substrate-free Forms of Cytochrome P450epoK J.Biol.Chem., 278, 2003
1Q5D	Epothilone B-bound Cytochrome P450epoK Descriptor: 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE, P450 epoxidase, PROTOPORPHYRIN IX CONTAINING FE Authors: Nagano, S, Li, H, Shimizu, H, Nishida, C, Ogura, H, Ortiz de Montellano, P.R, Poulos, T.L. Deposit date: 2003-08-06 Release date: 2003-10-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK J.Biol.Chem., 278, 2003
8D1C	Crystal structure of T252E-CYP199A4 in complex with 4-(Trifluoromethoxy)benzoic acid Descriptor: 4-(trifluoromethoxy)benzoic acid, CHLORIDE ION, Cytochrome P450, ... Authors: Lee, J.H.Z, Bruning, J.B, Bell, S.G. Deposit date: 2022-05-27 Release date: 2023-03-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Selective Oxidations Using a Cytochrome P450 Enzyme Variant Driven with Surrogate Oxygen Donors and Light. Chemistry, 28, 2022
1PO5	Structure of mammalian cytochrome P450 2B4 Descriptor: Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE Authors: Scott, E.E, He, Y.A, Wester, M.R, White, M.A, Chin, C.C, Halpert, J.R, Johnson, E.F, Stout, C.D. Deposit date: 2003-06-13 Release date: 2003-10-07 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.6 Å) Cite: An open conformation of mammalian cytochrome P450 2B4 at 1.6 A resolution Proc.Natl.Acad.Sci.USA, 100, 2003
1PQ2	Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8 Descriptor: Cytochrome P450 2C8, PALMITIC ACID, PHOSPHATE ION, ... Authors: Schoch, G.A, Yano, J.K, Wester, M.R, Griffin, K.J, Stout, C.D, Johnson, E.F. Deposit date: 2003-06-17 Release date: 2004-01-13 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site J.Biol.Chem., 279, 2004
1N97	Crystal Structure of CYP175A1 from Thermus thermophillus strain HB27 Descriptor: 1,2-ETHANEDIOL, CYP175A1, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Yano, J.K, Blasco, F, Li, H, Schmid, R.D, Henne, A, Poulos, T.L. Deposit date: 2002-11-22 Release date: 2003-02-25 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Preliminary Characterization and Crystal Structure of a Thermostable Cytochrome P450 from Thermus thermophilus J.Biol.Chem., 278, 2003
8D8P	Crystal structure of a novel fatty acid decarboxylase from Rothia nasimurium Descriptor: Decarboxylase, PALMITIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Vieira, P.S, Murakami, M.T, Zanphorlin, L.M. Deposit date: 2022-06-08 Release date: 2023-05-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Crystal structure of a novel fatty acid decarboxylase from Rothia nasimurium Proc.Natl.Acad.Sci.USA, 2023
1OXA	CYTOCHROME P450 (DONOR:O2 OXIDOREDUCTASE) Descriptor: 6-DEOXYERYTHRONOLIDE B, CYTOCHROME P450 ERYF, PROTOPORPHYRIN IX CONTAINING FE Authors: Cupp-Vickery, J.R, Poulos, T.L. Deposit date: 1995-07-14 Release date: 1995-12-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of cytochrome P450eryF involved in erythromycin biosynthesis. Nat.Struct.Biol., 2, 1995
1OG5	Structure of human cytochrome P450 CYP2C9 Descriptor: CYTOCHROME P450 2C9, HEME C, S-WARFARIN Authors: Williams, P.A, Cosme, J, Ward, A, Angove, H.C, Matak Vinkovic, D, Jhoti, H. Deposit date: 2003-04-24 Release date: 2003-07-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Crystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin Nature, 424, 2003

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