6O2R
 
 | | Deacetylated Microtubules | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | | Deposit date: | 2019-02-24 | | Release date: | 2019-05-22 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Effects of alpha-tubulin acetylation on microtubule structure and stability.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6O2Q
 | | Acetylated Microtubules | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | | Deposit date: | 2019-02-24 | | Release date: | 2019-05-22 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Effects of alpha-tubulin acetylation on microtubule structure and stability.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6O5M
 | | Tubulin-RB3_SLD-TTL in complex with compound 10bb | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | | Authors: | Kumar, G, Wang, Y, Li, W, White, S.W. | | Deposit date: | 2019-03-04 | | Release date: | 2019-07-10 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin.
J.Med.Chem., 62, 2019
|
|
6O5N
 | | Tubulin-RB3_SLD-TTL in complex with compound 10ab | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Kumar, G, Wang, Y, Li, W, White, S.W. | | Deposit date: | 2019-03-04 | | Release date: | 2019-07-10 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.003 Å) | | Cite: | Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin.
J.Med.Chem., 62, 2019
|
|
6OJQ
 | |
6O61
 | | Tubulin-RB3_SLD-TTL in complex with compound ABI-231 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Kumar, G, Wang, Y, Li, W, White, S.W. | | Deposit date: | 2019-03-05 | | Release date: | 2019-07-10 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.599 Å) | | Cite: | Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin.
J.Med.Chem., 62, 2019
|
|
6PC4
 | | Tubulin-RB3_SLD-TTL in complex with compound ABI-274 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Kumar, G, Wang, Y, Li, W, White, S.W. | | Deposit date: | 2019-06-15 | | Release date: | 2020-04-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties.
J.Med.Chem., 63, 2020
|
|
1W5E
 | |
1W5F
 | | FtsZ, T7 mutated, domain swapped (T. maritima) | | Descriptor: | CELL DIVISION PROTEIN FTSZ, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Oliva, M.A, Cordell, S.C, Lowe, J. | | Deposit date: | 2004-08-06 | | Release date: | 2004-12-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Insights Into Ftsz Protofilament Formation
Nat.Struct.Mol.Biol., 11, 2004
|
|
1W5B
 | | FtsZ dimer, GTP soak (M. jannaschii) | | Descriptor: | CELL DIVISION PROTEIN FTSZ HOMOLOG 1, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Oliva, M.A, Cordell, S.C, Lowe, J. | | Deposit date: | 2004-08-06 | | Release date: | 2004-12-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Insights Into Ftsz Protofilament Formation
Nat.Struct.Mol.Biol., 11, 2004
|
|
1W5A
 | | FtsZ dimer, MgGTP soak (M. jannaschii) | | Descriptor: | CELL DIVISION PROTEIN FTSZ HOMOLOG 1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | Authors: | Oliva, M.A, Cordell, S.C, Lowe, J. | | Deposit date: | 2004-08-06 | | Release date: | 2004-12-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Insights Into Ftsz Protofilament Formation
Nat.Struct.Mol.Biol., 11, 2004
|
|
1W58
 | | FtsZ GMPCPP soak I213 (M. jannaschii) | | Descriptor: | CELL DIVISION PROTEIN FTSZ HOMOLOG 1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Oliva, M.A, Cordell, S.C, Lowe, J. | | Deposit date: | 2004-08-06 | | Release date: | 2004-12-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Insights Into Ftsz Protofilament Formation
Nat.Struct.Mol.Biol., 11, 2004
|
|
1W59
 | | FtsZ dimer, empty (M. jannaschii) | | Descriptor: | CELL DIVISION PROTEIN FTSZ HOMOLOG 1, SULFATE ION | | Authors: | Oliva, M.A, Cordell, S.C, Lowe, J. | | Deposit date: | 2004-08-06 | | Release date: | 2004-12-01 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Insights Into Ftsz Protofilament Formation
Nat.Struct.Mol.Biol., 11, 2004
|
|
6QVJ
 | | HsCKK (human CAMSAP1) decorated 14pf taxol-GDP microtubule | | Descriptor: | Calmodulin-regulated spectrin-associated protein 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Atherton, J.M, Luo, Y, Xiang, S, Yang, C, Jiang, K, Stangier, M, Vemu, A, Cook, A, Wang, S, Roll-Mecak, A, Steinmetz, M.O, Akhmanova, A, Baldus, M, Moores, C.A. | | Deposit date: | 2019-03-02 | | Release date: | 2019-11-27 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural determinants of microtubule minus end preference in CAMSAP CKK domains.
Nat Commun, 10, 2019
|
|
1Z2B
 | | Tubulin-colchicine-vinblastine: stathmin-like domain complex | | Descriptor: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Gigant, B, Wang, C, Ravelli, R.B.G, Roussi, F, Steinmetz, M.O, Curmi, P.A, Sobel, A, Knossow, M. | | Deposit date: | 2005-03-08 | | Release date: | 2005-05-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Structural basis for the regulation of tubulin by vinblastine.
Nature, 435, 2005
|
|
1Z5V
 | | Crystal structure of human gamma-tubulin bound to GTPgammaS | | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Tubulin gamma-1 chain | | Authors: | Aldaz, H.A, Rice, L.M, Stearns, T, Agard, D.A. | | Deposit date: | 2005-03-20 | | Release date: | 2005-05-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.
Nature, 435, 2005
|
|
1Z5W
 | | Crystal Structure of gamma-tubulin bound to GTP | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Tubulin gamma-1 chain | | Authors: | Aldaz, H.A, Rice, L.M, Stearns, T, Agard, D.A. | | Deposit date: | 2005-03-20 | | Release date: | 2005-05-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Insights into microtubule nucleation from the crystal structure of human gamma-tubulin.
Nature, 435, 2005
|
|
8F18
 | | Apo KIF20A[1-565] class-2 in complex with a microtubule | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ... | | Authors: | Benoit, M.P.M.H, Asenjo, A.B, Crozet, V, Ranaivoson, F.M, Houdusse, A, Sosa, H. | | Deposit date: | 2022-11-04 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Nucleotide-free structures of KIF20A illuminate atypical mechanochemistry in this kinesin-6.
Open Biology, 13, 2023
|
|
8F1A
 | | Apo KIF20A[1-565] class-1 in complex with a microtubule | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF20A, ... | | Authors: | Benoit, M.P.M.H, Asenjo, A.B, Crozet, V, Ranaivoson, F.M, Houdusse, A, Sosa, H. | | Deposit date: | 2022-11-04 | | Release date: | 2023-09-20 | | Last modified: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Nucleotide-free structures of KIF20A illuminate atypical mechanochemistry in this kinesin-6.
Open Biology, 13, 2023
|
|
8G2Z
 | | 48-nm doublet microtubule from Tetrahymena thermophila strain CU428 | | Descriptor: | B2B3_fMIP, B5B6_fMIP, CFAM166A, ... | | Authors: | Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. | | Deposit date: | 2023-02-06 | | Release date: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins.
Nat Commun, 14, 2023
|
|
8G3D
 | | 48-nm doublet microtubule from Tetrahymena thermophila strain K40R | | Descriptor: | B2B3_fMIP, B5B6_fMIP, CFAM166A, ... | | Authors: | Black, C.S, Kubo, S, Yang, S.K, Bui, K.H. | | Deposit date: | 2023-02-07 | | Release date: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins.
Nat Commun, 14, 2023
|
|
2P4N
 | |
8GZW
 | | Klebsiella pneumoniae FtsZ complexed with monobody (P21) | | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Monobody | | Authors: | Matsumura, H, Yoshizawa, T, Fujita, J, Tanaka, S, Amesaka, H. | | Deposit date: | 2022-09-27 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
|
|
8GZV
 | | Klebsiella pneumoniae FtsZ complexed with monobody (P212121) | | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Monobody | | Authors: | Matsumura, H, Yoshizawa, T, Fujita, J, Tanaka, S, Amesaka, H. | | Deposit date: | 2022-09-27 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
|
|
8GZX
 | | Escherichia coli FtsZ complexed with monobody (P212121) | | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, Monobody | | Authors: | Matsumura, H, Yoshizawa, T, Fujita, J, Tanaka, S, Amesaka, H. | | Deposit date: | 2022-09-27 | | Release date: | 2023-07-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
|
|
