PDB: 909 resultsInfo pagesStatus searchChemie searchBIRD

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4TLQ	Crystal structure of C-terminal RNA recognition motif of human ELAV type RNA binding protein-3 at 2.5 Angstrom resolution Descriptor: CUGBP Elav-like family member 2 Authors: Kashyap, M, Bhavesh, N.S. Deposit date: 2014-05-30 Release date: 2015-12-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.503 Å) Cite: Crystal structure of C-terminal RNA recognition motif of human ELAV type RNA binding protein-3 at 2.5 Angstrom resolution To Be Published
7LHX	Human U1A protein with F37M and F77M mutations for improved phasing Descriptor: ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ... Authors: Jenkins, J.L, Lippa, G.M, Wedekind, J.E. Deposit date: 2021-01-26 Release date: 2021-03-17 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing Crystals, 11, 2021
6DCL	Crystal structure of UP1 bound to pri-miRNA-18a terminal loop Descriptor: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3') Authors: Kooshapur, H, Sattler, M. Deposit date: 2018-05-07 Release date: 2018-06-27 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.497 Å) Cite: Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1. Nat Commun, 9, 2018
6DG0	MEC-8 C-terminal RRM domain bound to AGCACA Descriptor: DNA (5'-D(*AP*GP*CP*AP*CP*A)-3'), Mec-8 protein Authors: Mackereth, C.D, Soufari, H. Deposit date: 2018-05-16 Release date: 2019-08-21 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.457 Å) Cite: Structure of MEC-8 RRM2 in complex with AGCACA To Be Published
7S3A	Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit Authors: Jenkins, J.L, Henderson, S, Kielkopf, C.L. Deposit date: 2021-09-05 Release date: 2022-05-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7S3B	Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Jenkins, J.L, Henderson, S, Kielkopf, C.L. Deposit date: 2021-09-05 Release date: 2022-05-25 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
7S3C	Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit Authors: Glasser, E, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2021-09-05 Release date: 2022-05-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal. Nucleic Acids Res., 50, 2022
6DG1	NMR structure of the second qRRM2 domain of human hnRNP H Descriptor: qRRM2 domain of Heterogeneous nuclear ribonucleoprotein H2 Authors: Srinivasa, R.P. Deposit date: 2018-05-16 Release date: 2018-09-05 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H. J. Am. Chem. Soc., 2018
1AUD	U1A-UTRRNA, NMR, 31 STRUCTURES Descriptor: RNA 3UTR, U1A 102 Authors: Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. Deposit date: 1997-08-22 Release date: 1998-02-25 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural basis of the RNA-binding specificity of human U1A protein. EMBO J., 16, 1997
7SN6	U2AF65 UHM BOUND TO SF3B155 ULM5 Descriptor: ISOPROPYL ALCOHOL, Splicing factor 3B subunit 1, Splicing factor U2AF 65 kDa subunit Authors: Loerch, S, Jenkins, J.L, Kielkopf, C.L. Deposit date: 2021-10-27 Release date: 2022-07-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing. J.Biol.Chem., 298, 2022
6E4N	Structure of the T. brucei TbRGG2 RRM domain: apo R3 crystal form Descriptor: RNA-binding protein, putative Authors: Schumacher, M.A. Deposit date: 2018-07-18 Release date: 2018-12-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.801 Å) Cite: The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA. Nucleic Acids Res., 47, 2019
6E4O	Structure of apo T. brucei RRM: P4(1)2(1)2 form Descriptor: RNA-binding protein, putative Authors: Schumacher, M.A. Deposit date: 2018-07-18 Release date: 2018-12-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA. Nucleic Acids Res., 47, 2019
6E4P	Structure of the T. brucei RRM domain in complex with RNA Descriptor: RNA (5'-R(P*UP*UP*UP*U)-3'), RNA-binding protein, putative Authors: Schumacher, M.A. Deposit date: 2018-07-18 Release date: 2018-12-12 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.949 Å) Cite: The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA. Nucleic Acids Res., 47, 2019
6ELD	Crystal structure of TIA-1 RRM1 in complex with U1C Descriptor: Nucleolysin TIA-1 isoform p40,U1 small nuclear ribonucleoprotein C Authors: Jagtap, P.K.A, Sattler, M. Deposit date: 2017-09-28 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.485 Å) Cite: Crystal structure of TIA-1 RRM1 in complex with U1C To Be Published
4Z2X	Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from mouse at 2.15 A resolution Descriptor: Splicing factor U2AF 65 kDa subunit Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2015-03-30 Release date: 2015-04-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from mouse at 2.15 A resolution To be published
4ZKA	High Resolution Crystal Structure of Fox1 RRM Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, RNA binding protein fox-1 homolog 1, SULFATE ION, ... Authors: Blatter, M, Allain, F.H.-T. Deposit date: 2015-04-30 Release date: 2016-06-29 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: High Resolution Crystal Structure of Fox1 RRM To Be Published
1D8Z	SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN (RBD1) OF HU ANTIGEN C (HUC) Descriptor: HU ANTIGEN C Authors: Inoue, M, Muto, Y, Sakamoto, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 1999-10-26 Release date: 2000-04-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C. Nucleic Acids Res., 28, 2000
1IQT	Solution structure of the C-terminal RNA-binding domain of heterogeneous nuclear ribonucleoprotein D0 (AUF1) Descriptor: heterogeneous nuclear ribonucleoprotein D0 Authors: Katahira, M, Miyanoiri, Y, Enokizono, Y, Matsuda, G, Nagata, T, Ishikawa, F, Uesugi, S. Deposit date: 2001-08-01 Release date: 2002-08-07 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA. J.Mol.Biol., 311, 2001
1D9A	SOLUTION STRUCTURE OF THE SECOND RNA-BINDING DOMAIN (RBD2) OF HU ANTIGEN C (HUC) Descriptor: HU ANTIGEN C Authors: Inoue, M, Muto, Y, Sakamoto, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 1999-10-26 Release date: 2000-04-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C. Nucleic Acids Res., 28, 2000
4YB1	20A Mutant c-di-GMP Vc2 Riboswitch bound with 3',3'-cGAMP Descriptor: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, MAGNESIUM ION, RNA (91-MER), ... Authors: Ren, A.M, Patel, D.J, Rajashankar, R.K. Deposit date: 2015-02-18 Release date: 2015-04-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.081 Å) Cite: Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch. Cell Rep, 11, 2015
1CVJ	X-RAY CRYSTAL STRUCTURE OF THE POLY(A)-BINDING PROTEIN IN COMPLEX WITH POLYADENYLATE RNA Descriptor: 5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', ADENOSINE MONOPHOSPHATE, POLYADENYLATE BINDING PROTEIN 1 Authors: Deo, R.C, Bonanno, J.B, Sonenberg, N, Burley, S.K. Deposit date: 1999-08-23 Release date: 1999-10-04 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Recognition of polyadenylate RNA by the poly(A)-binding protein. Cell(Cambridge,Mass.), 98, 1999
1JMT	X-ray Structure of a Core U2AF65/U2AF35 Heterodimer Descriptor: HEXANE-1,6-DIOL, SPLICING FACTOR U2AF 35 KDA SUBUNIT, SPLICING FACTOR U2AF 65 KDA SUBUNIT Authors: Kielkopf, C.L, Rodionova, N.A, Green, M.R, Burley, S.K. Deposit date: 2001-07-19 Release date: 2001-09-19 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer. Cell(Cambridge,Mass.), 106, 2001
4YOE	Structure of UP1 bound to RNA 5'-AGU-3' Descriptor: ACETATE ION, Heterogeneous nuclear ribonucleoprotein A1, RNA AGU, ... Authors: Meagher, J.L, Stuckey, J.A. Deposit date: 2015-03-11 Release date: 2015-06-10 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.92 Å) Cite: The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein. J.Mol.Biol., 427, 2015
1L3K	UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 Descriptor: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 Authors: Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M. Deposit date: 2002-02-27 Release date: 2002-04-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1. Nucleic Acids Res., 30, 2002
1DZ5	The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein Descriptor: PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A Authors: Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G. Deposit date: 2000-02-16 Release date: 2000-03-29 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein Nat.Struct.Biol., 7, 2000

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