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8W26
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BU of 8w26 by Molmil
X-ray crystal structure of the GAF-PHY domains of SyB-Cph1
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, PHYCOCYANOBILIN, ...
Authors:Burgie, E.S, Vierstra, R.D.
Deposit date:2024-02-20
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Photosensory Module from a PAS-Less Cyanobacterial Phytochrome Reveals a Hybrid Activated Conformation in the Dark-Adapted Pr State
To Be Published
7CKV
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BU of 7ckv by Molmil
Crystal structure of Cyanobacteriochrome GAF domain in Pr state
Descriptor: MAGNESIUM ION, PHYCOCYANOBILIN, RcaE
Authors:Nagae, T, Koizumi, T, Hirose, Y, Mishima, M.
Deposit date:2020-07-19
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural basis of the protochromic green/red photocycle of the chromatic acclimation sensor RcaE.
Proc.Natl.Acad.Sci.USA, 118, 2021
5ZOH
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BU of 5zoh by Molmil
Crystal structure of a far-red light-absorbing form of AnPixJg2_BV4 in complex with biliverdin
Descriptor: BILIVERDINE IX ALPHA, GLYCEROL, Methyl-accepting chemotaxis protein
Authors:Miyazaki, T, Fushimi, K, Narikawa, R.
Deposit date:2018-04-13
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Rational conversion of chromophore selectivity of cyanobacteriochromes to accept mammalian intrinsic biliverdin.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
1YKD
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BU of 1ykd by Molmil
Crystal Structure of the Tandem GAF Domains from a Cyanobacterial Adenylyl Cyclase: Novel Modes of Ligand-Binding and Dimerization
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, adenylate cyclase
Authors:Martinez, S.E, Bruder, S, Schultz, A, Zheng, N, Schultz, J.E, Beavo, J.A, Linder, J.U.
Deposit date:2005-01-17
Release date:2005-02-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: Modes of ligand binding and dimerization
Proc.Natl.Acad.Sci.USA, 102, 2005
3DBA
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BU of 3dba by Molmil
Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C
Descriptor: Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GLYCEROL, GUANOSINE-3',5'-MONOPHOSPHATE
Authors:Martinez, S.E, Heikaus, C.C, Klevit, R.E, Beavo, J.A.
Deposit date:2008-05-30
Release date:2008-07-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:The Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change.
J.Biol.Chem., 283, 2008
6UVB
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BU of 6uvb by Molmil
Crystal structure of far-red-light absorbing cyanobacteriochrome at 100K
Descriptor: Multi-sensor signal transduction histidine kinase, PHYCOCYANOBILIN
Authors:Yang, X, Ren, Z, Bandara, S.
Deposit date:2019-11-01
Release date:2020-11-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a far-red-sensing cyanobacteriochrome reveals an atypical bilin conformation and spectral tuning mechanism.
Proc.Natl.Acad.Sci.USA, 118, 2021
6UPP
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BU of 6upp by Molmil
Radiation Damage Test of PixJ Pb state crystals
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Methyl-accepting chemotaxis protein, ...
Authors:Clinger, J.A, Miller, M.D, Burgie, E.S, Vierstra, R.D, Phillips Jr, G.N.
Deposit date:2019-10-18
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Photoreversible interconversion of a phytochrome photosensory module in the crystalline state.
Proc.Natl.Acad.Sci.USA, 117, 2020
5DFX
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BU of 5dfx by Molmil
Structure of the parental state of GAF3 from Slr1393 of Synechocystis sp. PCC6803 (in vivo assembled protein/chromophore)
Descriptor: Histidine kinase, PHYCOCYANOBILIN
Authors:Xu, X.-L, Zhao, K.-H, Gaertner, W, Hoeppner, A.
Deposit date:2015-08-27
Release date:2016-09-14
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural elements regulating the photochromicity in a cyanobacteriochrome
Proc.Natl.Acad.Sci.USA, 2020
3VV4
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BU of 3vv4 by Molmil
Crystal structure of cyanobacteriochrome TePixJ GAF domain
Descriptor: Methyl-accepting chemotaxis protein, Phycoviolobilin, green light-absorbing form, ...
Authors:Ishizuka, T, Narikawa, R, Muraki, N, Shiba, T, Kurisu, G, Ikeuchi, M.
Deposit date:2012-07-14
Release date:2013-01-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of cyanobacteriochromes from phototaxis regulators AnPixJ and TePixJ reveal general and specific photoconversion mechanism
Proc.Natl.Acad.Sci.USA, 110, 2013
6UV8
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BU of 6uv8 by Molmil
Crystal structure of a far-red cyanobacteriochrome photoreceptor at room temperature
Descriptor: Multi-sensor signal transduction histidine kinase, PHYCOCYANOBILIN
Authors:Yang, X, Ren, Z, Bandara, S.
Deposit date:2019-11-01
Release date:2020-11-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Crystal structure of a far-red-sensing cyanobacteriochrome reveals an atypical bilin conformation and spectral tuning mechanism.
Proc.Natl.Acad.Sci.USA, 118, 2021
3W2Z
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BU of 3w2z by Molmil
Crystal structure of the cyanobacterial protein
Descriptor: IODIDE ION, Methyl-accepting chemotaxis protein, PHYCOCYANOBILIN
Authors:Narikawa, R, Muraki, N, Shiba, T, Kurisu, G, Ikeuchi, M.
Deposit date:2012-12-06
Release date:2013-01-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of cyanobacteriochromes from phototaxis regulators AnPixJ and TePixJ reveal general and specific photoconversion mechanism
Proc.Natl.Acad.Sci.USA, 110, 2013
5DFY
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BU of 5dfy by Molmil
Structure of the parental state of GAF3 from Slr1393 of Synechocystis sp. PCC6803 (in vitro assembled protein/chromophore)
Descriptor: Histidine kinase, PHYCOCYANOBILIN
Authors:Xu, X.-L, Zhao, K.-H, Gaertner, W, Hoeppner, A.
Deposit date:2015-08-27
Release date:2016-09-14
Last modified:2020-01-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural elements regulating the photochromicity in a cyanobacteriochrome
Proc.Natl.Acad.Sci.USA, 2020
3CI6
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BU of 3ci6 by Molmil
Crystal structure of the GAF domain from Acinetobacter phosphoenolpyruvate-protein phosphotransferase
Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Cuff, M.E, Shackelford, G, Kim, Y, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-03-10
Release date:2008-05-13
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the GAF domain from Acinetobacter phosphoenolpyruvate-protein phosphotransferase.
TO BE PUBLISHED
2Y79
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BU of 2y79 by Molmil
STRUCTURE OF THE FIRST GAF DOMAIN E87A MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS
Descriptor: CALCIUM ION, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Cho, H.Y, Cho, H.J, Kang, B.S.
Deposit date:2011-01-30
Release date:2011-02-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Blockage of the Channel to Heme by the E87 Side Chain in the Gaf Domain of Mycobacterium Tuberculosis Doss Confers the Unique Sensitivity of Doss to Oxygen.
FEBS Lett., 585, 2011
2K31
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BU of 2k31 by Molmil
Solution Structure of cGMP-binding GAF domain of Phosphodiesterase 5
Descriptor: GUANOSINE-3',5'-MONOPHOSPHATE, Phosphodiesterase 5A, cGMP-specific
Authors:Heikaus, C.C, Stout, J.R, Sekharan, M.R, Eakin, C.M, Rajagopal, P, Brzovic, P.S, Beavo, J.A, Klevit, R.E.
Deposit date:2008-04-16
Release date:2008-06-03
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: Insights into Nucleotide Selectivity, Dimerization, and cGMP-Dependent Conformational Change.
J.Biol.Chem., 283, 2008
2K2N
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BU of 2k2n by Molmil
Solution structure of a cyanobacterial phytochrome GAF domain in the red light-absorbing ground state
Descriptor: PHYCOCYANOBILIN, Sensor protein
Authors:Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L.
Deposit date:2008-04-04
Release date:2008-09-23
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of a cyanobacterial phytochrome GAF domain in the red-light-absorbing ground state.
J.Mol.Biol., 383, 2008
2XSS
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BU of 2xss by Molmil
Crystal structure of GAFb from the human phosphodiesterase 5
Descriptor: CGMP-SPECIFIC 3', 5'-CYCLIC PHOSPHODIESTERASE
Authors:Schlicker, C, Russwurm, M, Steegborn, C.
Deposit date:2010-09-30
Release date:2011-05-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Gaf-B Domain from Human Phosphodiesterase 5.
Proteins, 79, 2011
2Y8H
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BU of 2y8h by Molmil
STRUCTURE OF THE FIRST GAF DOMAIN E87G MUTANT OF MYCOBACTERIUM TUBERCULOSIS DOSS
Descriptor: CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, TWO COMPONENT SENSOR HISTIDINE KINASE DEVS
Authors:Cho, H.Y, Cho, H.J, Kang, B.S.
Deposit date:2011-02-07
Release date:2011-02-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Blockage of the Channel to Heme by the E87 Side Chain in the Gaf Domain of Mycobacterium Tuberculosis Doss Confers the Unique Sensitivity of Doss to Oxygen.
FEBS Lett., 585, 2011
2KLI
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BU of 2kli by Molmil
Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form
Descriptor: PHYCOCYANOBILIN, Sensor protein
Authors:Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Zhang, J, Rivera, M, Vierstra, R.D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2009-07-03
Release date:2009-11-03
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural basis for the photoconversion of a phytochrome to the activated Pfr form
Nature, 463, 2010
2KOI
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BU of 2koi by Molmil
Refined solution structure of a cyanobacterial phytochrome GAF domain in the red light-absorbing ground state
Descriptor: PHYCOCYANOBILIN, Sensor protein
Authors:Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2009-09-22
Release date:2009-11-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the photoconversion of a phytochrome to the activated Pfr form
Nature, 463, 2010
8K9O
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BU of 8k9o by Molmil
Crystal structure of Cyanobacteriochrome RcaE GAF domain in Pg state
Descriptor: PHYCOCYANOBILIN, histidine kinase
Authors:Nagae, T, Hirose, Y, Mishima, M.
Deposit date:2023-08-01
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Green/red light-sensing mechanism in the chromatic acclimation photosensor
Sci Adv, 2024
3K2N
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BU of 3k2n by Molmil
The crystal structure of sigma-54-dependent transcriptional regulator domain from Chlorobium Tepidum TLS
Descriptor: Sigma-54-dependent transcriptional regulator
Authors:Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-09-30
Release date:2010-01-19
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of sigma-54-dependent transcriptional regulator domain from Chlorobium
To be Published
5W10
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BU of 5w10 by Molmil
Lcd1 GAF domain in complex with cAMP ligand
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cGMP-specific phosphodiesterase
Authors:Guzzo, C.R, Maciel, N.K, Barbosa, A.S, Farah, C.S.
Deposit date:2017-06-01
Release date:2017-06-28
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Enzymatic Characterization of a cAMP-Dependent Diguanylate Cyclase from Pathogenic Leptospira Species.
J. Mol. Biol., 429, 2017
3TRC
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BU of 3trc by Molmil
Structure of the GAF domain from a phosphoenolpyruvate-protein phosphotransferase (ptsP) from Coxiella burnetii
Descriptor: PHOSPHATE ION, Phosphoenolpyruvate-protein phosphotransferase, SODIUM ION
Authors:Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J.
Deposit date:2011-09-09
Release date:2011-09-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
4FOF
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BU of 4fof by Molmil
Crystal Structure of the blue-light absorbing form of the Thermosynechococcus elongatus PixJ GAF-domain
Descriptor: Methyl-accepting chemotaxis protein, Phycoviolobilin, blue light-absorbing form, ...
Authors:Burgie, E.S, Walker, J.M, Phillips Jr, G.N, Vierstra, R.D.
Deposit date:2012-06-20
Release date:2013-01-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.416 Å)
Cite:A Photo-Labile Thioether Linkage to Phycoviolobilin Provides the Foundation for the Blue/Green Photocycles in DXCF-Cyanobacteriochromes.
Structure, 21, 2013

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