3KIV
| RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A) | Descriptor: | 6-AMINOHEXANOIC ACID, APOLIPOPROTEIN | Authors: | Mochalkin, I, Tulinsky, A, Scanu, A. | Deposit date: | 1998-09-08 | Release date: | 1999-05-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Recombinant kringle IV-10 modules of human apolipoprotein(a): structure, ligand binding modes, and biological relevance. Biochemistry, 38, 1999
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5Z55
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8V8Z
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8V9B
| Lipoprotein(a) Kringle IV domain 7 - Lp(a) KIV7 in complex with LY3441732 | Descriptor: | (2S,2'S)-3,3'-[carbonylbis(azanediyl-3,1-phenylene)]bis{2-[(3R)-pyrrolidin-1-ium-3-yl]propanoate}, Apolipoprotein(a), MAGNESIUM ION, ... | Authors: | Hendle, J, Weichert, K, Sauder, J.M. | Deposit date: | 2023-12-07 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Lipoprotein(a) Kringle IV domains 7 and 8 - Lp(a) KIV7 and KIV8 in complex with LY3353871, LY3441732 and LY3473329 To Be Published
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1TPK
| CRYSTAL STRUCTURE OF THE KRINGLE-2 DOMAIN OF TISSUE PLASMINOGEN ACTIVATOR AT 2.4-ANGSTROMS RESOLUTION | Descriptor: | CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR | Authors: | De vos, A.M, Ultsch, M.H, Kelley, R.F, Padmanabhan, K, Tulinsky, A, Westbrook, M.L, Kossiakoff, A.A. | Deposit date: | 1991-09-24 | Release date: | 1992-07-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution. Biochemistry, 31, 1992
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6RX7
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7TNG
| Kringle domain of human Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) | Descriptor: | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | Authors: | Guarino, S.R, Di Bello, A, Palamini, M, Forneris, F. | Deposit date: | 2022-01-21 | Release date: | 2022-05-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1) Acta Crystallogr.,Sect.F, 78, 2022
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8TCE
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6OSV
| Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 | Descriptor: | Antibody heavy chain variable region, Antibody light chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2 | Authors: | Park, H, Rader, C. | Deposit date: | 2019-05-02 | Release date: | 2020-04-01 | Last modified: | 2020-05-13 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications. J.Biol.Chem., 295, 2020
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1URK
| SOLUTION STRUCTURE OF THE AMINO TERMINAL FRAGMENT OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR | Descriptor: | PLASMINOGEN ACTIVATOR, alpha-L-fucopyranose | Authors: | Hansen, A.P, Petros, A.M, Meadows, R.P, Nettesheim, D.G, Mazar, A.P, Olejniczak, E.T, Xu, R.X, Pederson, T.M, Henkin, J, Fesik, S.W. | Deposit date: | 1994-01-10 | Release date: | 1995-05-08 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the amino-terminal fragment of urokinase-type plasminogen activator. Biochemistry, 33, 1994
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4KIV
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5HPG
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2PK4
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6BA5
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6BAN
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2FEB
| NMR Solution Structure, Dynamics and Binding Properties of the Kringle IV Type 8 module of apolipoprotein(a) | Descriptor: | Apolipoprotein(a) | Authors: | Chitayat, S, Kanelis, V, Koschinsky, M.L, Smith, S.P. | Deposit date: | 2005-12-15 | Release date: | 2006-12-26 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Nuclear magnetic resonance (NMR) solution structure, dynamics, and binding properties of the kringle IV type 8 module of apolipoprotein(a). Biochemistry, 46, 2007
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1B2I
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1CEA
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1CEB
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1HPJ
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1HPK
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2I9A
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6OSN
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6OSH
| Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 | Descriptor: | Antibody Light chain variable region, Antibody heavy chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2 | Authors: | Park, H, Rader, C. | Deposit date: | 2019-05-01 | Release date: | 2020-04-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.117 Å) | Cite: | Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications. J.Biol.Chem., 295, 2020
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2KNF
| Solution structure and functional characterization of human plasminogen kringle 5 | Descriptor: | Plasminogen | Authors: | Battistel, M.D, Grishaev, A, An, S.A, Castellino, F.J, Llinas, M. | Deposit date: | 2009-08-21 | Release date: | 2009-10-27 | Last modified: | 2021-10-13 | Method: | SOLUTION NMR | Cite: | Solution structure and functional characterization of human plasminogen kringle 5. Biochemistry, 48, 2009
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