2UUQ
| |
2UVN
| Crystal structure of econazole-bound CYP130 from Mycobacterium tuberculosis | Descriptor: | 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, CYTOCHROME P450 130, FLUORIDE ION, ... | Authors: | Podust, L.M, Ortiz de Montellano, P.R. | Deposit date: | 2007-03-12 | Release date: | 2007-12-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mycobacterium Tuberculosis Cyp130: Crystal Structure, Biophysical Characterization, and Interactions with Antifungal Azole Drugs J.Biol.Chem., 283, 2008
|
|
2QBO
| Crystal structure of the P450cam G248V mutant in the cyanide bound state | Descriptor: | CAMPHOR, CYANIDE ION, Cytochrome P450-cam, ... | Authors: | von Koenig, K, Makris, T.M, Sligar, S.D, Schlichting, I. | Deposit date: | 2007-06-18 | Release date: | 2007-12-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Alteration of P450 Distal Pocket Solvent Leads to Impaired Proton Delivery and Changes in Heme Geometry. Biochemistry, 46, 2007
|
|
2QBN
| Crystal structure of ferric G248V cytochrome P450cam | Descriptor: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | Authors: | von Koenig, K, Makris, T.M, Sligar, S.D, Schlichting, I. | Deposit date: | 2007-06-18 | Release date: | 2007-12-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Alteration of P450 Distal Pocket Solvent Leads to Impaired Proton Delivery and Changes in Heme Geometry. Biochemistry, 46, 2007
|
|
2QBL
| Crystal structure of ferric G248T cytochrome P450cam | Descriptor: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | Authors: | von Koenig, K, Makris, T.M, Sligar, S.D, Schlichting, I. | Deposit date: | 2007-06-18 | Release date: | 2007-12-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Alteration of P450 Distal Pocket Solvent Leads to Impaired Proton Delivery and Changes in Heme Geometry. Biochemistry, 46, 2007
|
|
2QBM
| Crystal structure of the P450cam G248T mutant in the cyanide bound state | Descriptor: | CAMPHOR, CYANIDE ION, Cytochrome P450-cam, ... | Authors: | von Koenig, K, Makris, T.M, Sligar, S.D, Schlichting, I. | Deposit date: | 2007-06-18 | Release date: | 2007-12-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Alteration of P450 Distal Pocket Solvent Leads to Impaired Proton Delivery and Changes in Heme Geometry. Biochemistry, 46, 2007
|
|
2ZAX
| Crystal Structure of Ferric Cytochrome P450cam | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... | Authors: | Sakurai, K, Shimada, H, Harada, K, Hayashi, T, Tsukihara, T. | Deposit date: | 2007-10-11 | Release date: | 2008-01-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam J.Am.Chem.Soc., 130, 2008
|
|
2ZAW
| Crystal Structure of Ferric Cytochrome P450cam Reconstituted with 6-Methyl-6-depropionated Hemin | Descriptor: | 6-METHY-6-DEPROPIONATEHEMIN, CAMPHOR, CHLORIDE ION, ... | Authors: | Harada, K, Sakurai, K, Shimada, H, Tsukihara, T, Hayashi, T. | Deposit date: | 2007-10-11 | Release date: | 2008-01-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam J.Am.Chem.Soc., 130, 2008
|
|
2RFB
| Crystal Structure of a Cytochrome P450 from the Thermoacidophilic Archaeon Picrophilus Torridus | Descriptor: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Ho, W.W, Li, H, Poulos, T.L, Nishida, C.R, Ortiz de Montellano, P.R. | Deposit date: | 2007-09-28 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure and Properties of CYP231A2 from the Thermoacidophilic Archaeon Picrophilus torridus. Biochemistry, 47, 2008
|
|
2RFC
| Ligand bound (4-phenylimidazole) Crystal Structure of a Cytochrome P450 from the Thermoacidophilic Archaeon Picrophilus Torridus | Descriptor: | 4-PHENYL-1H-IMIDAZOLE, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ho, W.W, Li, H, Poulos, T.L, Nishida, C.R, Ortiz de Montellano, P.R. | Deposit date: | 2007-09-28 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structure and Properties of CYP231A2 from the Thermoacidophilic Archaeon Picrophilus torridus. Biochemistry, 47, 2008
|
|
3BE0
| The Role of Asn 242 in P450cin | Descriptor: | 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, P450cin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Meharenna, Y.T, Poulos, T.L. | Deposit date: | 2007-11-15 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in p450cin J.Biol.Chem., 283, 2008
|
|
3BDZ
| The Role of Asn 242 in P450cin | Descriptor: | MALONATE ION, P450cin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Meharenna, Y.T, Poulos, T.L. | Deposit date: | 2007-11-15 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in p450cin J.Biol.Chem., 283, 2008
|
|
3C6G
| Crystal structure of CYP2R1 in complex with vitamin D3 | Descriptor: | (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLI DENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Cytochrome P450 2R1, ... | Authors: | Strushkevich, N.V, Min, J, Loppnau, P, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Plotnikov, A.N, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-02-04 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural analysis of CYP2R1 in complex with vitamin D3. J.Mol.Biol., 380, 2008
|
|
2VKU
| 4,4'-Dihydroxybenzophenone Mimics Sterol Substrate in the Binding Site of Sterol 14alpha-Demethylase (CYP51) in the X-ray Structure of the Complex | Descriptor: | CYTOCHROME P450 51, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | Authors: | Eddine, A.N, von Kries, J.P, Podust, M.V, Podust, L.M. | Deposit date: | 2007-12-29 | Release date: | 2008-03-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | X-Ray Structure of 4,4'-Dihydroxybenzophenone Mimicking Sterol Substrate in the Active Site of Sterol 14Alpha-Demethylase (Cyp51) J.Biol.Chem., 283, 2008
|
|
2ZBY
| Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) | Descriptor: | Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | Deposit date: | 2007-10-30 | Release date: | 2008-04-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
|
|
2ZBX
| Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (wild type) with imidazole bound | Descriptor: | Cytochrome P450-SU1, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | Deposit date: | 2007-10-30 | Release date: | 2008-04-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
|
|
2ZBZ
| Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) in complex with 1,25-dihydroxyvitamin D3 | Descriptor: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. | Deposit date: | 2007-10-30 | Release date: | 2008-04-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
|
|
3BUJ
| Crystal Structure of CalO2 | Descriptor: | CalO2, PROTOPORPHYRIN IX CONTAINING FE | Authors: | McCoy, J.G, Johnson, H.D, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N. | Deposit date: | 2008-01-02 | Release date: | 2008-04-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway. Proteins, 74, 2009
|
|
2VN0
| CYP2C8DH COMPLEXED WITH TROGLITAZONE | Descriptor: | (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE, CYTOCHROME P450 2C8, PALMITIC ACID, ... | Authors: | Schoch, G.A, Yano, J.K, Sansen, S, Stout, C.D, Johnson, E.F. | Deposit date: | 2008-01-30 | Release date: | 2008-04-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid. J. Biol. Chem., 283, 2008
|
|
2VE4
| Substrate free cyanobacterial CYP120A1 | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 120 | Authors: | Kuhnel, K, Ke, N, Sligar, S.G, Schuler, M.A, Schlichting, I. | Deposit date: | 2007-10-16 | Release date: | 2008-04-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structures of Substrate-Free and Retinoic Acid-Bound Cyanobacterial Cytochrome P450 Cyp120A1. Biochemistry, 47, 2008
|
|
2VE3
| Retinoic acid bound cyanobacterial CYP120A1 | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 120, RETINOIC ACID | Authors: | Kuhnel, K, Ke, N, Sligar, S.G, Schuler, M.A, Schlichting, I. | Deposit date: | 2007-10-15 | Release date: | 2008-04-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Substrate-Free and Retinoic Acid-Bound Cyanobacterial Cytochrome P450 Cyp120A1. Biochemistry, 47, 2008
|
|
2Q9F
| Crystal structure of human cytochrome P450 46A1 in complex with cholesterol-3-sulphate | Descriptor: | CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Cytochrome P450 46A1, GLYCEROL, ... | Authors: | White, M.A, Mast, N.V, Johnson, E.F, Stout, C.D, Pikuleva, I.A. | Deposit date: | 2007-06-12 | Release date: | 2008-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
2Q9G
| Crystal structure of human cytochrome P450 46A1 | Descriptor: | Cytochrome P450 46A1, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE | Authors: | White, M.A, Mast, N.V, Johnson, E.F, Stout, C.D, Pikuleva, I.A. | Deposit date: | 2007-06-12 | Release date: | 2008-06-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
3CBD
| |
3CZH
| Crystal structure of CYP2R1 in complex with vitamin D2 | Descriptor: | (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Cytochrome P450 2R1, ... | Authors: | Strushkevich, N.V, Tempel, W, Gilep, A.A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-04-29 | Release date: | 2008-08-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of CYP2R1 in complex with vitamin D2. To be Published
|
|