1NGG
| STRUCTURAL BASIS OF THE 70-KILODALTON HEAT SHOCK COGNATE PROTEIN ATP HYDROLYTIC ACTIVITY, II. STRUCTURE OF THE ACTIVE SITE WITH ADP OR ATP BOUND TO WILD TYPE AND MUTANT ATPASE FRAGMENT | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, HEAT-SHOCK COGNATE 70 kD PROTEIN, MAGNESIUM ION | Authors: | Flaherty, K.M, Wilbanks, S.M, Deluca-Flaherty, C, Mckay, D.B. | Deposit date: | 1994-05-17 | Release date: | 1994-08-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. II. Structure of the active site with ADP or ATP bound to wild type and mutant ATPase fragment. J.Biol.Chem., 269, 1994
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3D2F
| Crystal structure of a complex of Sse1p and Hsp70 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Heat shock 70 kDa protein 1, ... | Authors: | Polier, S, Bracher, A. | Deposit date: | 2008-05-08 | Release date: | 2008-06-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the cooperation of Hsp70 and Hsp110 chaperones in protein folding. Cell(Cambridge,Mass.), 133, 2008
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1QQO
| E175S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, HYDROLASE (ACTING ON ACID ANHYDRIDES), ... | Authors: | Johnson, E.R, McKay, D.B. | Deposit date: | 1999-06-07 | Release date: | 1999-09-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein. Biochemistry, 38, 1999
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1NGH
| STRUCTURAL BASIS OF THE 70-KILODALTON HEAT SHOCK COGNATE PROTEIN ATP HYDROLYTIC ACTIVITY, II. STRUCTURE OF THE ACTIVE SITE WITH ADP OR ATP BOUND TO WILD TYPE AND MUTANT ATPASE FRAGMENT | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, HEAT-SHOCK COGNATE 70 kD PROTEIN | Authors: | Flaherty, K.M, Wilbanks, S.M, Deluca-Flaherty, C, Mckay, D.B. | Deposit date: | 1994-05-17 | Release date: | 1994-08-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. II. Structure of the active site with ADP or ATP bound to wild type and mutant ATPase fragment. J.Biol.Chem., 269, 1994
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7JMM
| Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RAKNIILLSR | Descriptor: | Alkaline phosphatase, Chaperone protein DnaK, SULFATE ION | Authors: | Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. | Deposit date: | 2020-08-02 | Release date: | 2020-08-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
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7JN8
| Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RGNTLVIVSR | Descriptor: | Alkaline phosphatase peptide, Chaperone protein DnaK, SULFATE ION | Authors: | Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. | Deposit date: | 2020-08-04 | Release date: | 2020-08-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
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3CQX
| Chaperone Complex | Descriptor: | BAG family molecular chaperone regulator 2, Heat shock cognate 71 kDa protein, SODIUM ION, ... | Authors: | Xu, Z, Nix, J.C, Misra, S. | Deposit date: | 2008-04-03 | Release date: | 2008-11-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of nucleotide exchange and client binding by the Hsp70 cochaperone Bag2 Nat.Struct.Mol.Biol., 15, 2008
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1QQN
| D206S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, D206S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN, ... | Authors: | Johnson, E.R, McKay, D.B. | Deposit date: | 1999-06-07 | Release date: | 1999-09-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein. Biochemistry, 38, 1999
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7KZI
| Intermediate state (QQQ) of near full-length DnaK alternatively fused with a substrate peptide | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Chaperone protein DnaK fused with substrate peptide,Chaperone protein DnaK fused with substrate peptide, ... | Authors: | Wang, W, Hendrickson, W.A. | Deposit date: | 2020-12-10 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides Acta Crystallogr.,Sect.D, 77, 2021
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7KZU
| Quasi-intermediate state (Q) of a truncated Hsp70 DnaK fused with a substrate peptide | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide,Chaperone protein DnaK fused with substrate peptide, GLYCEROL, ... | Authors: | Wang, W, Hendrickson, W.A. | Deposit date: | 2020-12-10 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Intermediates in allosteric equilibria of DnaK-ATP interactions with substrate peptides Acta Crystallogr.,Sect.D, 77, 2021
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1QQM
| D199S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, D199S MUTANT OF BOVINE 70 KILODALTON HEAT SHOCK PROTEIN, ... | Authors: | Johnson, E.R, Mckay, D.B. | Deposit date: | 1999-06-07 | Release date: | 1999-09-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein. Biochemistry, 38, 1999
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7KRU
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7KRT
| Restraining state of a truncated Hsp70 DnaK | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, MAGNESIUM ION | Authors: | Wang, W, Hendrickson, W.A. | Deposit date: | 2020-11-20 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
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7KRV
| Stimulating state of disulfide-bridged Hsp70 DnaK | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK fused with substrate peptide, MAGNESIUM ION, ... | Authors: | Wang, W, Hendrickson, W.A. | Deposit date: | 2020-11-20 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Conformational equilibria in allosteric control of Hsp70 chaperones. Mol.Cell, 81, 2021
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7KO2
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7KRW
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3DPO
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3DPP
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3DPQ
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3GDQ
| Crystal structure of the human 70kDa heat shock protein 1-like ATPase domain in complex with ADP and inorganic phosphate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Heat shock 70 kDa protein 1-like, ... | Authors: | Wisniewska, M, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Siponen, M, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Schueler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-02-24 | Release date: | 2009-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78 Plos One, 5, 2010
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4EZP
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4F01
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4EZT
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4EZR
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4EZW
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