PDB: 281 resultsInfo pagesStatus searchChemie searchBIRD

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7CPY	Lovastatin nonaketide synthase with LovC Descriptor: Lovastatin nonaketide synthase, enoyl reductase component lovC, polyketide synthase component, ... Authors: Wang, J, Wang, Z. Deposit date: 2020-08-08 Release date: 2021-01-13 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural basis for the biosynthesis of lovastatin. Nat Commun, 12, 2021
7CPX	Lovastatin nonaketide synthase Descriptor: Lovastatin nonaketide synthase, polyketide synthase component, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Wang, J, Wang, Z. Deposit date: 2020-08-08 Release date: 2021-01-13 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.91 Å) Cite: Structural basis for the biosynthesis of lovastatin. Nat Commun, 12, 2021
4CW4	Crystal structure of the noncanonical ketosynthase FabY from P. aeruginosa Descriptor: BETA-KETOACYL SYNTHASE, CHLORIDE ION, SULFATE ION Authors: Bukhari, H.S.T, Jakob, R.P, Maier, T. Deposit date: 2014-04-01 Release date: 2014-12-17 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.349 Å) Cite: Evolutionary Origins of the Multienzyme Architecture of Giant Fungal Fatty Acid Synthase. Structure, 22, 2014
4DDO	Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase ii from burkholderia vietnamiensis Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, SODIUM ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-01-19 Release date: 2012-05-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
7F27	Crystal structure of polyketide ketosynthase Descriptor: 3-oxoacyl-(Acyl-carrier-protein) synthase Authors: Kim, Y, Lee, W.C. Deposit date: 2021-06-10 Release date: 2022-06-15 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.806 Å) Cite: Structural basis of the complementary activity of two ketosynthases in aryl polyene biosynthesis. Sci Rep, 11, 2021
4EWG	Crystal structure of a Beta-ketoacyl synthase from Burkholderia phymatum STM815 Descriptor: 1,2-ETHANEDIOL, Beta-ketoacyl synthase, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-04-26 Release date: 2012-05-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
4F32	Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase II from Burkholderia vietnamiensis in complex with platencin Descriptor: 1,2-ETHANEDIOL, 2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-05-08 Release date: 2012-05-23 Last modified: 2014-02-12 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
5E5N	Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 1) Descriptor: Polyketide synthase PksL Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. Deposit date: 2015-10-08 Release date: 2015-11-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5E6K	Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 2) Descriptor: Polyketide synthase PksL, SULFATE ION Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. Deposit date: 2015-10-10 Release date: 2015-11-18 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.16 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
2GP6	X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB) Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2 Authors: Sridharan, S, Sacchettini, J, TB Structural Genomics Consortium (TBSGC) Deposit date: 2006-04-17 Release date: 2006-07-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: X-Ray Crystal Structure of Mycobacterium tuberculosis beta-Ketoacyl Acyl Carrier Protein Synthase II (mtKasB). J.Mol.Biol., 366, 2007
7TUI	Structure of C. albicans FAS in an inhibited state Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta Authors: Lou, J.W, Mazhab-Jafari, M.T. Deposit date: 2022-02-02 Release date: 2023-02-15 Method: ELECTRON MICROSCOPY (2.66 Å) Cite: Structure of C. albicans FAS in an inhibited state. To Be Published
2GQD	The crystal structure of B-ketoacyl-ACP synthase II (FabF) from Staphylococcus aureus Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2 Authors: Miller, D.J, White, S.W, Zhang, Y.M, Rock, C.O. Deposit date: 2006-04-20 Release date: 2006-05-02 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The crystal structure of B-ketoacyl-ACP synthase II (FabF) from Staphylococcus aureus To be Published
7UWR	KSQ+AT from first module of the pikromycin synthase Descriptor: Narbonolide/10-deoxymethynolide synthase PikA1, modules 1 and 2 Authors: Keatinge-Clay, A.T, Dickinson, M.S, Miyazawa, T, McCool, R.S. Deposit date: 2022-05-03 Release date: 2022-06-08 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (2.61 Å) Cite: Priming enzymes from the pikromycin synthase reveal how assembly-line ketosynthases catalyze carbon-carbon chemistry. Structure, 30, 2022
7ZMD	Ketosynthase domain of module 3 from Brevibacillus Brevis orphan BGC11 Descriptor: Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-04-19 Release date: 2022-09-21 Last modified: 2023-04-05 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7ZM9	Ketosynthase domain 3 of Brevibacillus Brevis orphan BGC11 Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-04-19 Release date: 2022-09-21 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.62 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7ZMA	Ketosynthase domain of module 4 from Brevibacillus Brevis orphan BGC11 Descriptor: Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-04-19 Release date: 2022-09-21 Last modified: 2023-04-05 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7ZMC	Ketosynthase domain of module 4 from Brevibacillus Brevis orphan BGC11 Descriptor: Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-04-19 Release date: 2022-09-21 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
5ELP	Ketosynthase from module 1 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 Descriptor: NRPS/PKS protein Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Zogzas, C.E. Deposit date: 2015-11-04 Release date: 2016-01-13 Last modified: 2016-11-02 Method: X-RAY DIFFRACTION (2.93 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5ERB	Ketosynthase from module 5 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 Descriptor: Polyketide synthase Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Meinke, J. Deposit date: 2015-11-13 Release date: 2015-12-23 Last modified: 2017-09-27 Method: X-RAY DIFFRACTION (4.2 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5ERF	Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 Descriptor: Polyketide synthase PksL Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. Deposit date: 2015-11-14 Release date: 2015-12-23 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
2HG4	Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS. Descriptor: 6-Deoxyerythronolide B Synthase, ACETATE ION, CHLORIDE ION, ... Authors: Tang, Y, Kim, C.Y, Mathews, I.I, Cane, D.E, Khosla, C. Deposit date: 2006-06-26 Release date: 2006-07-11 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.73 Å) Cite: The 2.7-A crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase. Proc.Natl.Acad.Sci.Usa, 103, 2006
5ENY	Ketosynthase from module 6 connected to acyl carrier protein from module 5 (unobservable) of the bacillaene synthase from Bacillus subtilis 168 Descriptor: Polyketide synthase PksL Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. Deposit date: 2015-11-09 Release date: 2015-12-23 Last modified: 2016-11-02 Method: X-RAY DIFFRACTION (4 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
7UK4	KS-AT di-domain of mycobacterial Pks13 with endogenous KS ligand bound Descriptor: Polyketide synthase PKS13, UNKNOWN LIGAND Authors: Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. Deposit date: 2022-03-31 Release date: 2023-02-15 Last modified: 2023-03-29 Method: ELECTRON MICROSCOPY (1.94 Å) Cite: Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
6KOG	Ketosynthase domain in tenuazonic acid synthetase 1 (TAS1). Descriptor: GLYCEROL, Hybrid PKS-NRPS synthetase TAS1, SULFATE ION Authors: Yun, C.S, Nishimoto, K, Motoyama, T, Hino, T, Nagano, S, Osada, H. Deposit date: 2019-08-10 Release date: 2020-07-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Unique features of the ketosynthase domain in a nonribosomal peptide synthetase-polyketide synthase hybrid enzyme, tenuazonic acid synthetase 1. J.Biol.Chem., 295, 2020
7ZSK	K3DAK4 bimodule core of BGC11 from Brevibacillus brevis. Descriptor: Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-05-07 Release date: 2022-09-21 Last modified: 2023-07-26 Method: ELECTRON MICROSCOPY (6.8 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022

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